Results 71 to 80 of about 41,740 (271)

Pain Management: A Flowsheet for Providers [PDF]

, 2018
Many different factors led to the trend of providers prescribing opioids for chronic pain. However, the misuse of and many deaths related to opioid prescriptions have caused the trend to reverse its direction. National organizations call for providers to
Swezey, Lisa
core   +1 more source

Exercise addiction risk and health in male and female amateur endurance cyclists [PDF]

, 2016
To determine the relationship between the risk of exercise addiction (REA) and health status in amateur endurance cyclists. Methods In 859 (751 men and 108 women) cyclists and 718 inactive subjects (307 men and 411 women), we examined the REA (Exercise
Legaz-Arrese, Alejandro, Mayolas-Pi, Carmen, Moliner-Urdiales, Diego, Munguía-Izquierdo, Diego, Peñarrubia-Lozano, Carlos, Simón-Grima, Javier   +5 more
core   +5 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Exercise dependence among customers from a Parisian sport shop [PDF]

, 2012
Aim of the study: We assessed exercise dependence (ED), alcohol and nicotine use disorders, eating disorders, hypochondria and compulsive buying and in a population of customers of a Parisian sport shop.
Chalvin, Florence, Guillot, Cecilia, Lejoyeux, Michel, Lequen, Valerie, Petit, Aymeric   +4 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Risks of exercise addiction and eating disorders among women attending fitness classes

Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2018
This article discusses the risks associated with exercise addiction (sport addiction) and eating disorders among women participating in fitness classes. The sample consisted of 190 women assigned to an experimental group (N=114) and healthy control group
O. V. Felsendorff, A. Y. Egorov
doaj  

An Interprofessional Consensus of Core Competencies for Prelicensure Education in Pain Management: Curriculum Application for Physical Therapy [PDF]

, 2013
Core competencies in pain management for prelicensure health professional education were recently established. These competencies represent the expectation of minimal capabilities for graduating health care students for pain management and include 4 ...
Bement, Marie K. Hoeger, Christensen, Nicole, Fishman, Scott M., Koebner, Ian J., Marie, Barbara J. St., Mongoven, Jennifer M., Nordstrom, Terry M., Sluka, Kathleen A.   +7 more
core   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

The Use of Image and Performance Enhancing Drugs During the Covid-19 Lockdown: a Cross-Cultural Study on Potential Users and Associated Risks

Emerging Trends in Drugs, Addictions, and Health
Introduction: Image and performance-enhancing drugs (IPEDs), or lifestyle drugs, are a wide range of products presented as having the potential to improve mental and physical function and health.
I. De Luca, F. Di Carlo, J. Burkauskas, A.R. Dores, M.A. Gómez-Martínez, A. Szabo, H. Fujiwara, C. Monteiro, M. Di Nicola, M. Mazza, G. Sani, D. Luciani, M. Pettorruso, M. di Giannantonio, I. Cataldo, G. Esposito, G. Martinotti, O. Corazza   +17 more
doaj   +1 more source

Adolescent brain cognitive development (ABCD) study: Overview of substance use assessment methods. [PDF]

, 2018
One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org/) is to establish a national longitudinal cohort of 9 and 10 year olds that will be followed for 10 years in order to prospectively study the risk and
Bartsch, Hauke, Conway, Kevin P, Feldstein Ewing, Sarah W, Goldstein, Rita Z, Gonzalez, Raul, Heitzeg, Mary, Lisdahl, Krista M, Nixon, Sara Jo, Sher, Kenneth J, Tapert, Susan   +9 more
core   +2 more sources