Results 81 to 90 of about 41,740 (271)

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Impulsivity and compulsivity as parallel mediators of emotion dysregulation in eating‐related addictive‐like behaviors, alcohol use, and compulsive exercise

Brain and Behavior, 2022
Introduction Transdiagnostically relevant psychological traits associated with psychiatric disorders are increasingly being researched, notably in substance use and addictive behaviors.
Emma Forsén Mantilla, David Clinton, Elin Monell, Johanna Levallius, Andreas Birgegård   +4 more
doaj   +1 more source

Food for Thought:A Randomised Controlled Trial of Emotional Freedom Techniques and Cognitive Behavioural Therapy in the Treatment of Food Cravings [PDF]

, 2016
Addressing the internal determinants of dysfunctional eating behaviours (e.g. food cravings) in the prevention and treatment of obesity has been increasingly recognised.
Bannatyne, Amy Jean, Porter, Brett, Sheldon, Terri, Stapleton, Peta, Urzi, Keri Charle   +4 more
core   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Clinical psychology of Internet addiction: a review of its conceptualization, prevalence, neuronal processes, and implications for treatment [PDF]

, 2015
Research into Internet addiction (IA) has grown rapidly over the last decade. The topic has generated a great deal of debate, particularly in relation to how IA can be defined conceptually as well as the many methodological limitations.
Griffiths, MD, Kuss, DJ, Pontes, HM
core   +1 more source

Propiedades Psicométricas del Exercise Addiction Inventory (EAI) en una Muestra de Estudiantes Brasileños Universitarios

Universitas Psychologica, 2017
El objetivo de este estudio fue validar el Inventario de Adicción al Ejercicio (EAI) en el contexto brasileño. Participaron en el estudio 251 estudiantes universitarios (hombres= 132, mujeres= 119, Medad = 22.34, DT = 4.65). Los resultados mostraron un adecuado ajuste del modelo a los datos: χ2 (9, N = 251) = 17.45, p = .04; χ2/gl = 1.94; CFI = .96 ...
Álvaro Sicilia, Valter Bracht, Vinicius Penha, Ueberson Ribero Almeida, Roberto Ferriz, Manuel Alcaraz-Ibáñez   +5 more
openaire   +3 more sources

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Relationship between E-sports and physical activity participation: Validation of the E-sports Addiction Scale (ESAS)

Baltic Journal of Health and Physical Activity
Background: E-sports are becoming increasingly popular. Considering the addictive potential of video games, e-sports might be more addictive than traditional sports.
Oliver SZABELLA, Lili KASSAY, Attila SZABO   +2 more
doaj   +1 more source

Obraz ciała u kobiet w ciąży oraz w połogu w zależności od zaangażowania w aktywność fizyczną

Fides et Ratio, 2020
Celem przeprowadzonych badań było określenie związku pomiędzy obrazem ciała a aktywnością fizyczną w grupie kobiet w ciąży oraz w połogu. Badania zostały zrealizowane przy użyciu dwóch kwestionariuszy w polskiej wersji językowej: The Exercise Addiction ...
Beata Ziółkowska, Kinga Ziółkowska
doaj   +1 more source