The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Comparing Patient Profiles In Total Knee Arthroplasty And Education And Exercise Therapy Programs For Knee Osteoarthritis [PDF]
, 2023 J.J. Young, M. Zywiel, A.V. Perruccio
openalex +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Pengaruh Penatalaksanaan Terapi Latihan Terhadap Kepuasan Pasien Fraktur Di Irina a Blu Rsup Prof. Dr. R.d. Kandou Manado [PDF]
, 2012 Rehabilitation treatment in patients with fractures include physical therapy, which consists of various types of exercises: isometric muscle exercises and active and passive ROM exercises.
Damping, H. H. (Hendrik)
core
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
The Clinical Outcomes of Exercise Therapy for a Soccer Player with Stress Fracture of Superior Pubic Ramus [PDF]
, 2014 Yong-Gon Seo, Won Hah Park
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Tango-therapy vs physical exercise in older people with dementia; a randomized controlled trial [PDF]
, 2023 Lucía Bracco +3 more
openalex +1 more source