Results 131 to 140 of about 873,384 (268)
Molecular Oncology, EarlyView.Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale +9 more
wiley +1 more source
Architecture of a Fuzzy Expert System Used for Dyslalic Children Therapy [PDF]
arXiv, 2014 In this paper we present architecture of a fuzzy expert system used for therapy of dyslalic children. With fuzzy approach we can create a better model for speech therapist decisions. A software interface was developed for validation of the system. The main objectives of this task are: personalized therapy (the therapy must be in according with child's ...
arxiv
Is exercise therapy the right treatment for rotator cuff-related shoulder pain: Uncertainties, theory, and practice [PDF]
BACKGROUND: Exercise therapy is a popular non-surgical treatment to help manage individuals with rotator cuff-related shoulder pain (RCRSP) and is recommended in all clinical practice guidelines.
Hing, Wayne +3 more
core +1 more source
Molecular Oncology, EarlyView.The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu +3 more
wiley +1 more source
Penatalaksanaan Fisioterapi Pada Kasus Cerebral Palsy Spastik Quadriplegi Tipe Ekstensi Di Yayasan Sayab Ibu Yogyakarta [PDF]
, 2015 Background : spastic quadriplegia cerebral palsy is a disorder of body posture disorders that are non- progressive movement that is caused by a lesion or abnormal development of the brain that are growing or unfinished growth characterized by increased ...
, Umi Budi Rahayu, SPd, SSt.Ft, M.Kes +1 more
core
Effect Of Theraband Exercise Therapy On Pain Reduction In Osteoarthritis Patients At Puskesmas Citra Medika Lubuklinggau City [PDF]
Theraband exercise, a type of elastic resistance exercise that allows many different movements to increase muscle strength, joint mobility, function and reduce joint pain in osteoarthritis sufferers.
Harison, Nunu +2 more
core +2 more sources
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam +2 more
wiley +1 more source
Molecular Oncology, EarlyView.This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou +13 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang +10 more
wiley +1 more source