Results 91 to 100 of about 933,719 (257)

Hypoxic transcription gene profiles under the modulation of nitric oxide in nuclear run on-microarray and proteomics [PDF]

, 2009
Background: Microarray analysis still remains a powerful tool to identify new components of the transcriptosome and it has helped to increase the knowledge of targets triggered by stress conditions such as hypoxia and nitric oxide.
Nathalie Dehne, Bernhard Brüne, Essler, Silke, Igwe, Emeka I., Silke Essler, Natalie Al-Furoukh, Igwe, Emeka I, Igwe Emeka I, Dehne, Nathalie, Essler Silke, Dehne Nathalie, Emeka I Igwe, Brüne, Bernhard, Al-Furoukh Natalie, Al-Furoukh, Natalie, Al-Furoukh, Natalie,, Brüne Bernhard   +16 more
core   +1 more source

Exhaled nitric oxide levels to guide treatment for children with asthma (Protocol) [PDF]

, 2015
This is the protocol for a review and there is no abstract. The objectives are as follows: To evaluate the efficacy of tailoring asthma medications based on exhaled nitric oxide (FeNO) for asthma related outcomes in children.
Petsky, Helen L, Jennifer A Kynaston, Petsky, HL, Kynaston, Jennifer, Kynaston, JA, Turner, Cathy, Cathy Turner, Anne B Chang, Chang, Anne B, Turner, C, Kew, Kayleigh, Helen L Petsky, Kew, KM, Kayleigh M Kew, Chang, AB   +14 more
core   +1 more source

Type‐2‐Inflammatory‐Diseases Share Comorbidities, Molecular Signatures, IL4/IL13 Genetics, and Response to IL4/IL13 Blockade

Allergy, EarlyView.
Studies suggest that type 2 inflammatory diseases are driven by overactivation of the IL4/IL13 pathway, manifesting differently in distinct tissues. We performed quantitative analyses using several large independent datasets to explore the interrelation of type 2 inflammatory diseases based on co‐prevalence, genetic predispositions, and transcriptomic ...
Jennifer D. Hamilton, Manuel A. R. Ferreira, Wei Keat Lim, Carlo Sidore, Matthew F. Wipperman, Wenzhen Ge, Xue Song, Changming Xia, Julie E. Horowitz, Andrea T. Hooper, Sara C. Hamon, Jennifer Maloney, Jamie M. Orengo, Zhen Chen, Stephanie Amato Ricci, Bolanle Akinlade, Aris Baras, Gary Herman, Brandy L. Bennett, George D. Yancopoulos   +19 more
wiley   +1 more source

Is Asthma Remission a New Achievable Goal? A Review of the Current Drug‐Related Evidence and Predictors

Allergy, EarlyView.
ABSTRACT Advances in asthma therapies have shown that clinical remission may be an achievable therapeutic goal for patients with asthma. This review discusses the current definitions of remission in asthma, the predictors of remission, airway inflammation/epithelial damage in asthma remission, airway remodeling, paradigms in defining remission and ...
Fatma Esra Gunaydin, Giulia Marcassa, Bianca Olivieri, Gianenrico Senna, Marco Caminati   +4 more
wiley   +1 more source

Exhaled nitric oxide correlates with airway eosinophils in childhood asthma [PDF]

, 2002
Background: Exhaled nitric oxide has been proposed as a marker for airway inflammation in asthma. The aim of this study was to compare exhaled nitric oxide levels with inflammatory cells and mediators in bronchoalveolar lavage fluid from asthmatic and ...
Ennis, Madeleine, Fitch, P.S., Taylor, R., Lyons, J.D., Brown, Vanessa, Shields, Michael, Warke, Timothy   +6 more
core   +1 more source

The gaseous messenger molecule, nitric oxide : a modulator of locomotor movements during early amphibian development [PDF]

, 2012
1. The free radical gas nitric oxide (NO) is now recognised as a ubiquitous and versatile signalling molecule and the investigation of its biological roles has involved a wide range of scientific disciplines in many different species. Yet despite this,
McLean, David L.
core   +2 more sources

Exhaled nitric oxide - circadian variations in healthy subjects

European Journal of Medical Research, 2009
Objective Exhaled nitric oxide (eNO) has been suggested as a marker of airway inflammatory diseases. The level of eNO is influenced by many various factor including age, sex, menstrual cycle, exercise, food, drugs, etc.
Antosova M, Bencova A, Psenkova A, Herle D, Rozborilova E   +4 more
doaj   +1 more source

Effect of Dupilumab on Airway Inflammation in Patients With Persistent Asthma

Allergy, EarlyView.
EXPEDITION (NCT02573233) assessed the effects of dupilumab on airway inflammation in patients with persistent asthma using bronchoscopy and gene expression analysis. Dupilumab showed no appreciable effect on inflammatory cell types in biopsies or BALF samples.
Michael E. Wechsler, Sally E. Wenzel, Steve D. Groshong, Mario Castro, Ian D. Pavord, Klaus F. Rabe, Elizabeth Laws, Alexandre Jagerschmidt, Kaitlyn Gayvert, Sivan Harel, Jennifer D. Hamilton, Nikhil Amin, Lu Zhang, Heming Xing, Anissa Elfakir, Bema Coulibaly, Souâd Naimi, Sara Hamon, Paul J. Rowe, Frank Nestle, Danen M. Cunoosamy, Emanuele de Rinaldis, Leda P. Mannent   +22 more
wiley   +1 more source

Nitric oxide sensing in plants is mediated by proteolytic control of group VII ERF transcription factors [PDF]

, 2014
Nitric oxide (NO) is an important signaling compound in prokaryotes and eukaryotes. In plants, NO regulates critical developmental transitions and stress responses.
Coego, Alberto, Gray, Julie E., Pearce, S. P., Theodoulou, F. L., Marin-De La Rosa, N., Pearce, Simon P, Gibbs, Daniel J., Mendiondo, G. M., Lozano-Juste, J., Bachmair, A., Movahedi, Mahsa, Lozano-Juste, Jorge, Hamali, B., Movahedi, M., Sousa Correia, Cristina, Gray, Julie E, Theodoulou, Frederica L, Talloji, P., Gibbs, D. J., Le�n, Jos�, Marín-De La Rosa, Nora Alicia, Pearce, Simon P., Correia, Cristina Sousa, Talloji, Prabhavathi, Tome, D. F. A., Bachmair, Andreas, Alabadí, David, Tomé, Daniel F.A., Holdsworth, Michael J, Alabadi, D., Bassel, George W., Vicente Conde, J. V., Md Isa, Nurulhikma, Tomé, Daniel F A, Tomé, Daniel F. A., Marín-de la Rosa, Nora, Bassel, George, Alabad�, David, Hamali, Bulut, Mar�n-de la Rosa, Nora, Mendiondo, Guillermina M, Vicente Conde, Jorge, Berckhan, S., Beynon, Jim, Berckhan, Sophie, León, José, Tom�, Daniel F.A., Coego, A., Holdsworth, M. J., Isa, N. M., Isa, Nurulhikma M. D., Sousa Correia, C., Mendiondo, Guillermina M., Conde, Jorge Vicente, Coego González, Alberto, Leon, J., Bassel, G. W., Holdsworth, Michael J., Theodoulou, Frederica L., Gibbs, Daniel J; id_orcid, Bassel, George W, Beynon, J., ALABADÍ DIEGO, DAVID, Gray, J. E.   +63 more
core   +1 more source

Bidirectional link between upper and lower airways in patients with allergic rhinitis

European Journal of Medical Research, 2009
Objective Exhaled nitric oxide has been proposed as a noninvasive marker of eosinophilic airway inflammation in lower airways. The aim of the study was to investigate the impact of atopy, pollen exposure, and pharmacological treatment on NO production in
Bencova A, Rozborilova E, Antosova M
doaj   +1 more source