Results 71 to 80 of about 933,719 (257)

Insulin-stimulated phosphorylation of endothelial nitric oxide synthase at serine-615 contributes to nitric oxide synthesis [PDF]

, 2009
Insulin stimulates endothelial NO (nitric oxide) synthesis via PKB (protein kinase B)/Akt-mediated phosphorylation and activation of eNOS (endothelial NO synthase) at Ser-1177.
Boyd, Alasdair R., Stuart A. Ritchie, Ian P. Salt, Salt, Ian P., Kohlhaas, Christine F, Yalla, Krishna C, Kohlhaas, Christine F., Boyd, Alasdair R, Krishna C. Yalla, Walsh, Kenneth, Ritchie, Stuart A, John M. C. Connell, Christine F. Kohlhaas, Kenneth Walsh, Ritchie, Stuart A., Connell, John M.C., Connell, John Mc, Salt, Ian P, Alasdair R. Boyd, Yalla, Krishna C.   +19 more
core   +1 more source

Prenatal vitamin d supplementation and child respiratory health: a randomised controlled trial.

PLoS ONE, 2013
BackgroundObservational studies suggest high prenatal vitamin D intake may be associated with reduced childhood wheezing. We examined the effect of prenatal vitamin D on childhood wheezing in an interventional study.MethodsWe randomised 180 pregnant ...
Stephen T Goldring, Chris J Griffiths, Adrian R Martineau, Stephen Robinson, Christina Yu, Sheree Poulton, Jane C Kirkby, Janet Stocks, Richard Hooper, Seif O Shaheen, John O Warner, Robert J Boyle   +11 more
doaj   +1 more source

Small Airways Dysfunction and Remission in Adults With Asthma: A Longitudinal Exploratory Analysis of the AssessmenT of smalL Airways involvemeNT In aSthma (ATLANTIS) Study

Allergy, EarlyView.
We conducted a post hoc analysis of ATLANTIS, a multinational prospective study including 684 adults with asthma. Fewer small airway symptoms and lower disease activity are independently associated with asthma remission. Replicated airway transcriptomic signatures show increased IL‐4/13 signalling and reduced coagulation pathways across the ATLANTIS ...
Akshi Kumar, Rory Chan, Nazanin Zounemat‐Kermani, Eleanor Quek, Ian M. Adcock, Bianca Beghe, Christopher Brightling, Dave Singh, Janwillem Kocks, Alberto Papi, Klaus F. Rabe, Ulrica Scaffidi‐Argentina, Maarten van den Berge, Monica Kraft, Salman Siddiqui   +14 more
wiley   +1 more source

Clinical Utility of Exhaled Nitric Oxide [PDF]

, 2013
Lower airway inflammation is generally classified as eosinophilic or neutrophilic. In conditions where eosinophilic inflammation predominates such as asthma in children, corticosteroids are usually beneficial.
Petsky, Helen, Petsky, Helen L.
core  

MEASUREMENT OF NITRIC OXIDE IN EXHALED AIR AS AN INSTRUMENT OF MONITORING BASIC THERAPY EFFICACY IN CHILDREN WITH BRONCHIAL ASTHMA

Педиатрическая фармакология, 2006
An individual approach to prescribing the most effective therapy for bronchial asthma is one of the actual problems of pediatric. It necessitates the development of new diagnostic markers of disease activity.
S.E. Tsyplenkova
doaj   +2 more sources

L-Arginine Supplementation and Metabolism in Asthma

Pharmaceuticals, 2011
L-Arginine, the amino acid substrate for nitric oxide synthase, has been tested as a therapeutic intervention in a variety of chronic diseases and is commonly used as a nutritional supplement.
Angela Linderholm, Nicholas J. Kenyon, Erin O’Roark, Vivian W. Kwan, Jennifer M. Bratt, Michael Last   +5 more
doaj   +1 more source

Exhaled Volatile Organic Compounds Identify Allergic Patients Among Individuals With Chronic Rhinitis

Allergy, EarlyView.
Exhaled decane and nonadecane discriminate allergic (AR + LAR) from non‐allergic (NAR + HC) subjects among individuals with chronic rhinitis. LAR patients display higher levels of exhaled nonadecane than NAR individuals at baseline. Subjects with FeNO≥ 25 ppb have higher levels of exhaled decane, nonanal, and styrene than individuals with FeNO < 25 ppb
Rosa Alba Sola‐Martinez, Laura Zubiaga‐Fernandez, Marta Figuerola, Anyith Cruz‐Amaya, Carlos J. Aranda, Maria J. Torres, Ibon Eguiluz‐Gracia, Carmen Rondon, Teresa De Diego Puente, Almudena Testera‐Montes   +9 more
wiley   +1 more source

The Role of Exhaled Breath Analyses in Interstitial Lung Disease

Diagnostics
Interstitial lung diseases (ILDs) represent a group of lung disorders that primarily affect the lung parenchyma. These disorders are usually progressive, may be debilitating and life threatening, and often pose diagnostic and therapeutic challenges ...
Panaiotis Finamore, Alessio Marinelli, Simone Scarlata, Silvano Dragonieri, Andras Bikov   +4 more
doaj   +1 more source

Evaluation of Acute Exogenous Hypoxia Impact on the Fraction of Exhaled Nitric Oxide in Healthy Males

Folia Medica, 2015
Introduction: Exogenous hypoxia increases ventilation and contracts the pulmonary vessels. Whether those factors change the values of nitric oxide in exhaled air has not yet been evaluated. Objective: To examine the effect of exogenous normobaric hypoxia
Dimov Peter K., Marinov Blagoi I., Ilchev Ilcho S., Taralov Zdravko Z., Kostianev Stefan S.   +4 more
doaj   +1 more source

Nasal and Exhaled Nitric Oxide in Allergic Rhinitis [PDF]

Clinical and Experimental Otorhinolaryngology, 2012
ObjectivesThe primary aim of this study was to assess whether one can use levels of nasal nitric oxide (nNO) and exhaled nitric oxide (eNO) as a means of evaluation in allergic rhinitis.MethodsWe used a chemiluminescence analyzer to measure nNO and eNO ...
Keon Jung Lee, Seok Hyun Cho, Seung Hwan Lee, Kyung Tae, Ho Joo Yoon, Sang Heon Kim, Jin Hyeok Jeong   +6 more
doaj   +1 more source