Results 61 to 70 of about 933,719 (257)

Inhaled Corticosteroid Escalation After a Single Moderate Exacerbation in COPD: Differential Benefit by Exacerbation Subtype

Respirology, EarlyView.
We tested whether ICS escalation after a single moderate COPD exacerbation improved outcomes according to exacerbation treatment phenotype. ICS reduced future exacerbations only in steroid‐treated events, not antibiotic‐treated events. This study supports phenotype‐guided escalation after one moderate exacerbation, avoiding overtreatment with precise ...
Sun Hye Shin, Jihye Heo, Ji Ye Jung, Juhee Cho, Dave Singh, Danbee Kang, Hye Yun Park   +6 more
wiley   +1 more source

[Exhaled nitric oxide].

Allergologia et immunopathologia, 2000
Nitric oxide is a molecule that under normal conditions is synthesised from L-arginine, thanks to the action of the so called NOS-c (nitric oxide synthethase constituents) in different cells, in very small amounts. They behave like a neurotransmitter, modulating different vascular functions of the flat muscle in the aerial vias.
S, Osanai, H, Ide, Y, Yamamoto, H, Nakano, K, Kikuchi   +4 more
openaire   +3 more sources

Exhaled nitric oxide and inducible nitric oxide synthase gene polymorphism in Japanese asthmatics

Allergology International, 2016
Background: Inducible nitric oxide synthase (iNOS) induced by inflammatory cytokines and iNOS activity in bronchial epithelial cells is a major determinant of fractional exhaled nitric oxide (FeNO) levels.
Suguru Sato, Xintao Wang, Junpei Saito, Atsuro Fukuhara, Manabu Uematsu, Yasuhito Suzuki, Yuki Sato, Kenichi Misa, Takefumi Nikaido, Naoko Fukuhara, Yoshinori Tanino, Mitsuru Munakata   +11 more
doaj   +1 more source

Role Of Exhaled Nitric Oxide As A Predictor Of Atopy [PDF]

D39. EVALUATION AND MONITORING OF ASTHMA AND COPD, 2012
Abstract Background The fractional exhaled nitric oxide (FeNO) is a quantitative, noninvasive and safe measure of airways inflammation that may complement the assessment of asthma. Elevations of FeNO have recently been found to correlate with allergic sensitization.
Romero, Karina M., Robinson, Colin L., Baumann, Lauren M., Gilman, Robert H., Hamilton, Robert G., Hansel, Nadia N, Checkley, William, PURA Study Investigators   +7 more
openaire   +6 more sources

Sargassum Lung Syndrome: Air Flow Obstruction and Bronchial Inflammation Are Observed After Prolonged Exposure to Sargassum Gas Emissions in the Eastern Caribbean

Environmental Toxicology, EarlyView.
ABSTRACT Sargassum inundation of Caribbean and American shorelines is a growing environmental hazard. Hydrogen sulfide (H2S) and ammonia (NH3) produced by decomposing Sargassum could be involved in airway obstruction and bronchial inflammation. The study was undertaken to evaluate the effects of exposure to H2S and NH3 gases emitted during Sargassum ...
Rishika Banydeen, Jonathan Florentin, Maxime Boutourlinsky, Remi Nguyen, Fatima Radouani, Moustapha Agossou, Gary Lutin, Thierry Lebrun, Remi Neviere, Dabor Resiere   +9 more
wiley   +1 more source

Exhaled nitric oxide levels to guide treatment for adults with asthma

, 2015
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To evaluate the efficacy of tailoring asthma interventions based on exhaled nitric oxide (FeNO) in comparison to not using FeNO i.e.
Anne B Chang, Jennifer A Kynaston, Petsky, HL, Turner, C, Helen L Petsky, Kynaston, JA, Kew, KM, Kayleigh M Kew, Cathy Turner, Chang, AB   +9 more
core   +1 more source

Use of Exhaled Nitric Oxide as a Biomarker in Diagnosis and Management of Chronic Obstructive Pulmonary Disease

Journal of Primary Care & Community Health, 2016
Background: Chronic obstructive pulmonary disease (COPD), a progressive and nonreversible disease, is a leading cause of mortality and morbidity throughout the world.
Ahmed A. Arif, Colin Mitchell
doaj   +1 more source

Safety, Efficacy, and Mechanism of Action of Budesonide in Rhinitis and Rhinosinusitis: A Systematic Review

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Budesonide is a corticosteroid with unique pharmacokinetic and pharmacodynamic properties that has been a frontline treatment for patients with allergic rhinitis (AR) and chronic rhinosinusitis (CRS) since the 1990s. As research on budesonide continues to produce new insights, our aim was to synthesize recent investigations and ...
David W. Kennedy, Lei Cheng, De‐Yun Wang   +2 more
wiley   +1 more source

Role of nitric oxide in airway inflammation and hyperresponsiveness in bronchial asthma

Allergology International, 1999
Nitric oxide (NO) is produced within the airways and has a variety of actions on the airway function. Nitric oxide is a potent bronchodilator, and NO released from airway epithelial cells and inhibitory nonadrenergic non-cholinergic nerve terminals may ...
Hisamichi Aizawa
doaj   +1 more source

The Global Airways Unit: A Multidisciplinary Strategy for Early Diagnosis and Comorbidity Detection

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic respiratory diseases impose a large global burden of morbidity, mortality, and cost. The concept of a global airway has become increasingly supported by epidemiologic, mechanistic, and clinical evidence. However, clinical care often remains fragmented between ear, nose, and throat (ENT), allergy, and pulmonology.
Diego M. Conti, Eduardo J. Correa, Alfonso Del Cuvillo, José D. Abdullatif, Francisco J. Alvarez‐Gutiérrez, Remedios Cárdenas Contreras, Stefan Cimbollek, Rocío Corrales Millán, Ana Gómez‐Bastero Fernández, Daniel Pérez‐Chada, Francisco Pérez‐Grimaldi, Alberto E. Rabino, Maria A. Romero‐Falcón, Marcela Soria, José Gregorio Soto‐Campos, Rosario B. Spuches, Juan Maza‐Solano   +16 more
wiley   +1 more source