Results 101 to 110 of about 933,719 (257)
Natural History of Alternaria Sensitisation and Association With Asthma and Rhinitis From Childhood to Adulthood
Allergy, EarlyView.We aimed to characterise Alternaria sensitisation trajectories from childhood to adulthood; we compared SPT, whole‐extract sIgE and rAlt a 1, and assessed their longitudinal association with asthma and rhinitis in the Isle of Wight birth cohort. Alternaria sensitisation in the Isle of Wight Birth Cohort emerges mainly in late adolescence and, when ...Mohammad Leily, Hongmei Zhang, Graham Roberts, Pandurangan Vijayanand, Magnus Bores, Eva Södergren, Ramesh J. Kurukulaaratchy, S. Hasan Arshad +7 morewiley +1 more sourceReference values for exhaled nitric oxide (reveno) study
Respiratory Research, 2006 Background Despite the widespread use of fractional exhaled nitric oxide (FENO) as a biomarker of airways inflammation, there are no published papers describing normal FENO values in a large group of healthy adults. Objective The aim of this study was to Mutti Antonio, Perbellini Luigi, Corradi Massimo, Talamini Giorgio, Olivieri Mario, Tantucci Claudio, Malerba Mario +6 moredoaj +1 more sourceSerotonin Degradation and Lipid Metabolism Regulate Human Tc2 Cell Effector Functions
Allergy, EarlyView.Human Tc2 cells exhibit a metabolically active phenotype characterized by enhanced glycolysis, mitochondrial respiration, and fatty acid uptake dependent on PPARγ. Alarmins strongly amplify IL‐5 and IL‐13 production in Tc2 cells, supporting a shared immunometabolic program across type 2 lymphocytes.Sabrina de Souza Ferreira, Lisa Holla, Sophia Björkander, Marie Kaarup Bek, Lorenz Wirth, Patrick A. Shearer, Jesper Säfholm, Erik Sachs, Mamdoh Al‐Ameri, Kasra Vali, Sandra Ekström, Erik Melén, Jenny Mjösberg, Christopher Andrew Tibbitt +13 morewiley +1 more sourceAn observational analysis on the influence of parental allergic rhinitis, asthma and smoking on exhaled nitric oxide in offspring [PDF]
BACKGROUND: Parental allergic diseases and smoking influence respiratory disease in the offspring but it is not known whether they influence fractional exhaled nitric oxide (FeNO) in the offspring.Dharmage, S.C.,, Svanes, C., Schlünssen, V,, Schlünssen, V., Svanes, C,, Johannessen, A, Jögi, N.O.,, Malinovschi, A,, Malinovschi, A., Bertelsen, R.J.,, Schlünssen, V, Abramson, M.J.,, Olin, A. C., Jõgi, R., Jõgi, R,, Zaigham, S.,, Dharmage, S C, Jögi, N.O., Forsberg, Bertil, Olin, A.C., Dharmage, S.C., Bertelsen, R J,, Gomez, L Palacios, Olin, A C, Holm, Mathias,, Malinovschi, Andrei,, Malinovschi, A.,, Lund University., Forsberg, B., Jõgi, R.,, Holm, M, Dharmage, S. C., Forsberg, B,, Schlünssen, V.,, Svanes, C, Bertelsen, R. J., Jõgi, R, Svanes, C.,, Holm, M,, Forsberg, B.,, Holm, M., Sigsgaard, T., Sigsgaard, T,, Oudin, A.,, Abramson, M J, Zaigham, Suneela,, Janson, C.,, Abramson, M J,, Schluenssen, V., Oudin, A., Abramson, M.J., Oudin, A,, Nerpin, Elisabet, Jögi, N O, Zaigham, S, Jögi, N O,, Holm, M.,, Nerpin, E.,, Bertelsen, Randi Jacobsen, Nerpin, E, Nerpin, E., Janson, Christer,, Janson, C., Olin, A C,, Oudin, Anna,, Abramson, M. J.,, Janson, C,, Jögi, N. O., Forsberg, B, Nerpin, Elisabet,, Janson, C, Oudin, Anna, Sigsgaard, T.,, Malinovschi, A, Jögi, Nils Oskar, Gomez, L. Palacios, Bertelsen, R. J.,, Olin, A.C.,, Dharmage, S. C.,, Abramson, M. J., Johannessen, A,, Forsberg, Bertil,, Janson, Christer, Johannessen, A., Olin, A. C.,, Gomez, L. Palacios,, Bertelsen, R J, Dharmage, S C,, Bertelsen, R.J., Jögi, N. O.,, Sigsgaard, T, Malinovschi, Andrei, Johannessen, A.,, Gomez, L Palacios,, Svanes, Cecilie, Zaigham, S., Zaigham, Suneela, Zaigham, S,, Oudin, A, Johannessen, Ane +99 morecore +1 more sourceEconomic Evaluation of the Use of FeNO for the Diagnosis and Management of Asthma Patients in Primary Care in Sweden
ClinicoEconomics and Outcomes Research, 2021 Josep Darbà,1 Meritxell Ascanio,2 Jörgen Syk,3– 5 Kjell Alving4 1Department of Economics, Universitat de Barcelona, Barcelona, Spain; 2BCN Health Economics & Outcomes Research, S.L., Barcelona, Spain; 3Department of Neurobiology ...Darbà J, Ascanio M, Syk J, Alving Kdoaj Remission in Global Airway Diseases: EUFOREA Consensus Paper
Allergy, EarlyView.ABSTRACT
The therapeutic goal in chronic airway diseases is shifting from symptom control to disease remission. Disease‐modifying therapies, including biologics and allergen immunotherapy, have made remission achievable in patients with severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), or allergic rhinitis (AR).J. Christian Virchow, Xander Bertels, Vibeke Backer, Benjamin S. Bleier, Marco Caminati, Diego M. Conti, Eugenio De Corso, Mina Gaga, Valerie J. Lund, Corrado Pelaia, Anju T. Peters, Glenis K. Scadding, Martin Wagenmann, Riyad O. Al‐Lehebi, Guy G. Brusselle, Philippe Gevaert, Liam G. Heaney, Stella E. Lee, Florence Schleich, Frederik Trinkmann, Peter W. Hellings, Wytske J. Fokkens, Paola Rogliani +22 morewiley +1 more sourceExhaled and nasal nitric oxide in laryngectomized patients
BMC Pulmonary Medicine, 2010 Background Nitric oxide (NO) shows differing concentrations in lower and upper airways. Patients after total laryngectomy are the only individuals, in whom a complete separation of upper and lower airways is guaranteed.Jörres Rudolf A, Nowak Dennis, de la Motte Dorothea, Bihler Annette, Olzowy Bernhard, Kramer Matthias F, Dressel Holger +6 moredoaj +1 more sourceClinical Features of Cellular Senescence Pathways in Severe Asthma
Allergy, EarlyView.In bronchial biopsies, SASP and p53 pathway enrichment scores are elevated in severe asthma versus non‐severe asthma and healthy controls. SASP enrichment is validated in the independent NOVA cohort. SASP enrichment is also elevated in nasal brushings of participants with nasal polyps, independently of asthma status.Woo‐Jung Song, Nazanin Zounemat Kermani, Ali Versi, Stephany Sánchez‐Ovando, Jodie Louise Simpson, Peter A. Wark, Katherine Joanne Baines, Sven‐Erik Dahlén, Ratko Djukanovic, Yike Guo, Ian M. Adcock, Kian Fan Chung, on behalf of the U‐BIOPRED Study Group, Mahmoud. I. Abdel‐Aziz, Ian M. Adcock, Lars I. Andersson, Charles Auffray, Yusef E. Badi, Per Bakke, Aruna T. Bansal, Frederic Baribaud, Stewart A. Bates, Elisabeth H. Bel, Jeanette Bigler, Bo Billing, Hans Bisgaard, Michael J. Boedigheimer, Klaus Bønnelykke, Joost Brandsma, Paul Brinkman, Enrica Bucchioni, Dominic Burg, Andrew Bush, Massimo Caruso, Romanas Chaleckis, Pascal Chanez, Kian Fan Chung, T. Checa, Chris H. Compton, Julie Corfield, Danen Cunoosamy, Arnaldo D'Amico, Barbro Dahlén, Sven‐Erik Dahlén, Bertrand De Meulder, Ratko Djukanovic, Veit J. Erpenbeck, Damijan Erzen, K. Fichtner, Louise J. Fleming, Elena Formaggio, Stephen J. Fowler, Urs Frey, Martina Gahlemann, Thomas Geiser, Victoria Goss, Yike Guo, Simone Hashimoto, John Haughney, Gunilla Hedlin, Pieter‐Paul W. Hekking, Timothy Higenbottam, Jens M. Hohlfeld, Cecile Holweg, Ildiko Horvath, Peter Howarth, Anna J. James, Richard G. Knowles, Johan Kolmert, Jon Konradsen, Norbert Krug, Nikos Lazarinis, C.‐X. Li, Matthew J. Loza, Rene Lutter, Alexander Manta, Sarah Masefield, Anke H. Maitland‐van der Zee, John G. Matthews, Alexander Mazein, Roelinde J. M. Middelveld, Montserrat Miralpeix, Paolo Montuschi, Jacek Musial, Sharon Mumby, David Myles, Björn Nordlund, Ioannis Pandis, Stelios Pavlidis, Anthony Postle, P. Powel, G. Praticò, M. Puig Valls, N. Rao, Stacey Reinke, John Riley, Amanda Roberts, Graham Roberts, Anthony Rowe, Thomas Sandström, Jim P. R. Schofield, Wolfgang Seibold, Dominic E. Shaw, R. Sigmund, Florian Singer, Paul J. Skipp, M. Smicker, Ana R. Sousa, Maria Sparreman‐Mikus, Peter J. Sterk, Marika Ström, Kai Sun, Bob Thornton, Mohib Uddin, Ali Versi, Jorgen Vestbo, Nadja H. Vissing, Scott S. Wagers, Åsa Wheelock, Craig E. Wheelock, Susan J. Wilson, Valentyna Yasinska, Nazanin Zounemat Kermani +122 morewiley +1 more source
