Results 71 to 80 of about 604,131 (324)
Identification of T cell exhaustion-related genes in clear cell renal cell carcinoma and construction of a prognostic model [PDF]
, 2023 Qi Wang +8 more
openalex +1 more source
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Autonomic dysregulation in burnout and depression: evidence for the central role of exhaustion
Scandinavian Journal of Work, Environment & Health, 2017 OBJECTIVES: Given the important role of the autonomic nervous system (ANS) in stress regulation, astonishingly little is known about ANS functioning in burnout, a condition arising after prolonged exposure to work-related stress. The current study sought
Magdalena K Kanthak +5 more
doaj +1 more source
Aging and Cancer, EarlyView.Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
Commercial extinction: The exhaustion of exhaustion [PDF]
, 2018 This contribution addresses the technosocial assemblages that constitute commercial extinction that are not included within the common definition. That is, that a species’ population is so depleted that is no longer profitable to harvest. Extinct for the
Gallardo, Francisco, Samson, Audrey
core
Effects of synchronous music on treadmill running among elite triathletes [PDF]
, 2012 This is the post-print version of the final paper published in Journal of Science and Medicine in Sport. The published article is available from the link below.
Alessandra Mecozzi Saha +33 more
core +3 more sources
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Approaching the relationship between emotional intelligence, burnout and academic commitment in students of compulsory secondary education [PDF]
, 2019 Introducción. En el proceso educativo de niños y adolescentes en los centros escolares se producen numerosas situaciones personales y contextuales que afectan de manera significativa a los estudiantes en su proceso de formación.
Salavera Bordás, Carlos +2 more
core +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Negotiating Worldly Relationships
Ardeth, 2021 Workers and nature are exhausted by architectural production. WE ARE TIRED. As a trade union of architectural workers in the UK, UVW-SAW members reflect on the project of workplace organising as renegotiating relationships: between workers, and the world.
United Voices of the World – Section of Architectural Workers (UVW-SAW)
doaj