Results 111 to 120 of about 2,695,064 (284)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Existence of a positive solution for a
Boundary Value Problems, 2005 We consider the boundary value problem in satisfying on , where on , is a parameter, is a bounded domain in with boundary , and for . Here, is a nondecreasing function for some satisfying (semipositone).
Shivaji R, Chhetri Maya
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Existence of Positive Solution to a Quasilinear Elliptic Problem in RN [PDF]
Surveys in Mathematics and its Applications, 2006 In this paper we prove the existence of positive solution for the following quasilinear problem ∆pu = a(x)f(u) in RN u > l >0 in RN u(x) → l, as |x| → ∞ where ∆p(1 < p < ∞) is the p -Laplacian operator.The proof is based on the results due to Diaz-Saa ...
Dragos-Patru Covei
doaj
On the existence of a periodic solution of a nonlinear ordinary differential equation
International Journal of Mathematics and Mathematical Sciences, 1998 Consider a planar forced system of the following form {dxdt=μ(x,y)+h(t)dydt=−ν(x,y)+g(t), where h(t) and g(t) are 2π-periodic continuous functions, t∈(−∞,∞) and μ(x,y) and ν(x,y) are continuous and satisfy local Lipschitz conditions.
Hsin Chu, Sunhong Ding
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Existence and Uniqueness of Solution for a Class of Stochastic Differential Equations
The Scientific World Journal, 2013 A class of stochastic differential equations given by dx(t)=f(x(t))dt+g(x(t))dW(t), x(t0)=x0, t0≤t ...
Junfei Cao, Zaitang Huang, Caibin Zeng
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Existence of weak-renormalized solution for a nonlinear system
Revista Matemática Complutense, 2002 We prove an existence result for a coupled system of the reactiondiffusion kind. The fact that no growth condition is assumed on some nonlinear terms motivates the search of a weak-renormalized solution.
openaire +4 more sources