Results 121 to 130 of about 504,503 (314)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Existence and Uniqueness of Solution for a Class of Stochastic Differential Equations
The Scientific World Journal, 2013 A class of stochastic differential equations given by dx(t)=f(x(t))dt+g(x(t))dW(t), x(t0)=x0, t0≤t ...
Junfei Cao, Zaitang Huang, Caibin Zeng
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Existence and uniqueness of solution for a singular elliptic differential equation
Advances in Nonlinear AnalysisIn this article, we are concerned about the existence, uniqueness, and nonexistence of the positive solution for: −Δu−12(x⋅∇u)=μh(x)uq−1+λu−up,x∈RN,u(x)→0,as∣x∣→+∞,\left\{\begin{array}{l}-\Delta u-\frac{1}{2}\left(x\cdot \nabla u)=\mu h\left(x){u}^{q-1}+\
Gu Shanshan, Yang Bianxia, Shao Wenrui
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On the Existence of Undominated Elements of Acyclic Relations [PDF]
We study the existence of undominated elements of acyclic and irreflexive relations. A sufficient condition for the existence is given in the general case without any topological assumptions.
Hannu Vartiainen, Hannu Salonen
core
Existence of a unique solution to a quasilinear elliptic equation
, 2011 The purpose of this paper is to prove the existence of a unique classical solution u(x) to the quasilinear elliptic equation −∇⋅(a(u)∇u)+v⋅∇u=f, where u(x0)=u0 at x0∈Ω and where n⋅∇u=g on the boundary ∂Ω. We prove that if the functions a, f, v, g satisfy
Denny, D., D. Denny, Denny, Diane
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Existence of radial sign-changing solution for a fractional autonomous Kirchhoff equation
四川大学学报. 自然科学版, 2020 The existence of sign-changing solutions for a fractional autonomous Kirchhoff equation is considered in the whole space. We prove that this equation is equivalent to a fractional autonomous Schr&odinger system under appropriate conditions.
ZHANG Dan-dan, DING Ling
doaj
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source