Results 141 to 150 of about 504,503 (314)
Existence of periodic solution for fourth-order generalized neutral p-Laplacian differential equation with attractive and repulsive singularities. [PDF]
J Inequal Appl, 2018 Xin Y, Liu H.
europepmc +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Some existence and uniqueness results for a solution of a system of equations
Applied General TopologyThis paper presents some existence and uniqueness results for a system of mappings on the finite product of metric spaces. Our results extend and generalize the well-known and celebrated results of Boyd and Wong [Proc. Amer. Math. Soc.
Deepak Khantwal, Rajendra Pant
doaj +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Existence of a unique solution to an elliptic partial differential equation
Electronic Journal of Differential Equations, 2019 The purpose of this article is to prove the existence of a unique classical solution to the quasilinear elliptic equation $-\nabla \cdot(a(u) \nabla u)=f$ for $\mathbf{x} \in \Omega$, which satisfies the condition that $u(\mathbf{x}_0)=u_0$ at a ...
Diane L. Denny
doaj
Coalitional Equilibria of Strategic Games [PDF]
Let N be a set of players, C the set of permissible coalitions and G an N-playerstrategic game. A profile is a coalitional-equilibrium if no coalition permissible coalition in C has a unilateral deviation that profits to all its members.
Rida Laraki
core
A note on the existence of solution for semilinear heat equations with polynomial growth nonlinearity [PDF]
, 1993 summary:The existence of weak solution for periodic-Dirichlet problem to semilinear heat equations with superlinear growth non-linear term is ...
Kim, Wan Se
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source