Results 111 to 120 of about 251,066 (317)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
The structure and existence of solutions of the problem of consumption with satiation in continuous time. [PDF]
Smoczynski P, Miles S.
europepmc +1 more source
In this article, we study the existence of solutions to first order non-linear initial value problems within the field of "dynamic equations on time scales". We employ the method of upper and lower solutions and Schauder's fixed point theorem.
Atiya H. Zaidi
doaj
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
The existence of solutions of q-difference-differential equations. [PDF]
Wang XL, Wang H, Xu HY.
europepmc +1 more source
Existence and non-existence of solutions for a p(x)-biharmonic problem
In this article, we study the following problem with Navier boundary conditions $$\displaylines{ \Delta (|\Delta u|^{p(x)-2}\Delta u)+|u|^{p(x)-2}u =\lambda |u|^{q(x)-2}u +\mu|u|^{\gamma(x)-2}u\quad \text{in } \Omega,\cr u=\Delta u=0 \quad \text{on
Ghasem A. Afrouzi +2 more
doaj
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
New applications of the existence of solutions for equilibrium equations with Neumann type boundary condition. [PDF]
Ji Z, Liu T, Tian H, Ülker T.
europepmc +1 more source

