Results 111 to 120 of about 401,314 (299)

Timpul parusiei în învățăturile lui Isus Hristos (partea I)

open access: yesTheoRhēma, 2019
In parallel with the formation of millennial dreams in Europe and America, the 19th century witnessed how rationalism, secularism, and skepticism permeated NT studies, including eschatology. The quest for the historical Jesus revealed a non-supernatural
Laurențiu Florentin Moț
doaj  

Existential questions in (relatively) hyperbolic groups {\it and} Finding relative hyperbolic structures

open access: yes, 2008
This arXived paper has two independant parts, that are improved and corrected versions of different parts of a single paper once named "On equations in relatively hyperbolic groups".
A. Kharlampovich   +19 more
core   +3 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

You Sluice and hai Modification in Chinese

open access: yesStudies in Chinese Linguistics, 2017
This paper argues that you ‘have’ sluice is a variant of pseudosluicing, akin to shi ‘be’ sluice in Chinese. You sluice can be analyzed as a base-generated structure [pro you ‘have’ wh-phrase], consisting of a subject pro, a verb you ‘have’, and a wh ...
Wei Ting-Chi
doaj   +1 more source

The Existential Passage Hypothesis [PDF]

open access: yes
[Excerpt from “Section 1: Summary of the conclusions”] In Chapter 9, Stewart defends the thesis that if non-reductive physicalism is true, then, contrary to a widespread belief, death does not bring about eternal oblivion, a permanent cessation of the ...
Robert, David
core  

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

The Existential Dimension in Recovery: Crisis, Loss, and Grief in the Context of Severe Mental Illness

open access: yesReligions
The recovery movement in mental health care has played an important role in the recent renewed and growing focus on understanding the function of meaning and spirituality in the context of severe mental illness.
Bernice Brijan   +2 more
doaj   +1 more source

Superintelligence as a Cause or Cure for Risks of Astronomical Suffering [PDF]

open access: yes, 2017
Discussions about the possible consequences of creating superintelligence have included the possibility of existential risk, often understood mainly as the risk of human extinction. We argue that suffering risks (s-risks) , where an adverse outcome would
Gloor, Lukas, Sotala, Kaj
core  

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