Results 91 to 100 of about 401,314 (299)

Existential Process in Harry Potter and the Chamber of Secret: a Systemic Functional Linguistic Study [PDF]

open access: yes, 2016
Dealing with sense of experience people undergo, transitivity construes the process of the experiences. One of the processes in transitivity is discussed here, that is existential process.
Afrianto, A. (Afrianto)   +1 more
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

The Effectiveness of Spiritual-based Existential Therapy and Positive Existential Therapy on Resiliency of Elderly Women

open access: yesتحقیقات نظام سلامت, 2020
Background: This study is conducted with the aim of determining the effectiveness of spiritual-based existential therapy and positive existential therapy on resiliency of elderly women. Methods: The present study was a quasi-experimental study with three
Afsaneh Sartipzadeh   +2 more
doaj  

WILL TO TRUTH IN THE PHILOSOPHY OF PRAGMATISM

open access: yesAntropologìčnì Vimìri Fìlosofsʹkih Doslìdžen', 2017
Purpose. Since the clear statement of the will-to-truth question as an existential has not been fulfilled before, this article is devoted to the solution of such a task.
D. Y. Snitko
doaj   +1 more source

No Rest for the Wicked? Symposium on Irene McMullin’s Existential Flourishing [PDF]

open access: yes, 2020
Irene McMullin’s Existential Flourishing (Cambridge University Press, 2018) weaves together virtue ethics and existential phenomenology: the influence of Heidegger and Levinas, in particular, is clear throughout. This paper provides a summary of McMullin’
Golob, Sacha
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

“Nothing Sacred”: Violence, Time and Meaning in the Cinema of Possibilities

open access: yesReligions, 2017
Hemingway’s disenchantment with the idea of the sacred as expressed in A Farewell to Arms became a defining aspect of the modern experience including in some Hollywood films such as Nothing Sacred and Twentieth Century.
Sam B. Girgus
doaj   +1 more source

The copula and existential verbs in Qiang [PDF]

open access: yes, 2010
This paper discusses the copula and existential verb constructions in Qiang, a Tibeto-Burman language of northern Sichuan ...
Huang, Chenglong, LaPolla, Randy J.
core  

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