Results 61 to 70 of about 4,720 (242)

Existential structures as specialised constructions

ELAD-SILDA
This constructionist paper deals with the specialised manifestations that constructions can exhibit and considers two questions: (i) how such specialised manifestations can be linked back to the cognitive architecture of the domain, (ii) whether we can, in this regard, speak about specialised constructions, for which (a) domain-related features ...
Vince Liégeois, Laurent Gautier
openaire   +5 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Construction, validity and reliability of existential anxiety questionnaire (QFEA)

روانشناسی بالینی و شخصیت, 2016
Introductoin: The purpose of present research was to design Existential anxiety questionnaire (death, freedom, loneliness and meaninglessness) and investigate its validity and reliability.
Raheleh Masoudi Sani, Bahman Bahmani, Ali Asgari, Mohammad Saeid Khanjani, Nassim Pakniya   +4 more
doaj  

Existential Constructions and Constructions Predicating Existence

, 2022
The term existential construction has been argued to be a misnomer, as the primary function of these constructions is not to predicate existence. In this study, I compare these constructions with ones whose primary function is to predicate existence using a stratified sample of European languages.
openaire   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Attribute-Based Signcryption: Signer Privacy, Strong Unforgeability and IND-CCA Security in Adaptive-Predicates Model (Extended Version) [PDF]

Journal of Internet Services and Information Security, 2016
Attribute-Based Signcryption (ABSC) is a natural extension of Attribute-Based Encryption (ABE) and Attribute-Based Signature (ABS), where one can have the message confidentiality and authenticity together. Since the signer privacy is captured in security
Tapas Pandit, Sumit Kumar Pandey, Rana Barua   +2 more
doaj  

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Le syntagme « existentiel » en breton : définition syntaxique et sémantique

La Bretagne Linguistique, 1989
In Breton, the construction of a so-called "existential" statement clearly involves the verb bezañ "to be" in its two forms zo and eus (avel a zo ; n’eus ket avel: "there is wind; there is no wind").
Jean-Yves Urien
doaj   +1 more source