Results 71 to 80 of about 61,755 (265)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Seismic Evaluated and Retrofit of Existing Buildings

Journal of Engineering and Sustainable Development, 2011
Most structures in Iraq were designed only for gravity loads, these make buildings present a major quandary for the person or agency concerned with reducing earthquake hazards.
Ilham Hatim Khuthair Alubaidi
doaj  

Predicting Renovation Risk in Existing Buildings Using Multilayer Perceptrons: Correlation-Based Feature Screening and Model Architecture Comparison

Applied Sciences
Renovation projects in existing university buildings involve considerable uncertainty due to incomplete documentation, aging building systems, phased execution, and the need to maintain ongoing educational activities during construction.
Agnieszka Leśniak, Olga Skrzypczak, Dominik Ożóg, Bartosz Leśniak, Michał Pietrzak   +4 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Energy Monitoring System for Existing Buildings in Indonesia

E3S Web of Conferences, 2018
Current studies conducted by JICA, AMPRI and IFC-World Bank, reported that large commercial buildings in Indonesia are not energy and water efficient. One of the cause is the lack of regulation. Meanwhile, effective regulations to reduce energy and water
Sesotya Utami Sentagi, Faridah, Azizi Na’im A., Kencanawati Erlin, Tanjung M. Akbar, Achmad Balza   +5 more
doaj   +1 more source

Carbon reduction technology pathways for existing buildings in eight cities. [PDF]

Nat Commun, 2023
Ang YQ, Berzolla ZM, Letellier-Duchesne S, Reinhart CF.   +3 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Developing Regenerate: A circular economy engagement tool for the assessment of new and existing buildings. [PDF]

J Ind Ecol, 2023
Gillott C, Mihkelson W, Lanau M, Cheshire D, Densley Tingley D.   +4 more
europepmc   +1 more source