Results 101 to 110 of about 21,117 (229)

High Score of ELST‐Blue in Endoscopic Ultrasonography Strain Elastography May Provide a High Risk Group of Early Chronic Pancreatitis with the Reduction of Apolipoprotein A2‐i Index

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Background To evaluate the usefulness of the ELST‐blue score to explore its potential application in identifying high‐risk groups for early chronic pancreatitis (ECP) through reflecting on pancreatic elasticity and the reduction of pancreatic function, and we tried to demonstrate whether the ELST‐blue score was significantly associated with ...
Ken Nakamura, Seiji Futagami, Shuhei Agawa, Sakura Higashida, Tomohide Tanabe, Takeshi Onda, Rie Kawawa, Mayu Habiro, Kumiko Kirita, Songyu Sai, Norio Itokawa, Nobue Ueki, Yoshiyuki Watanabe, Ryo Ohta, Nobuhiko Taniai, Kazufumi Honda, Katsuhiko Iwakiri, Masanori Atsukawa   +17 more
wiley   +1 more source

Loss of function variants in the primate-specific gene ZNF808 cause neonatal, transient and adult-onset diabetesResearch in context

EBioMedicine
Summary: Background: Biallelic loss-of-function ZNF808 variants were recently identified as a cause of pancreatic agenesis characterised by insulin-treated permanent neonatal diabetes (PNDM), low birthweight and exocrine pancreatic insufficiency ...
James Russ-Silsby, Kevin Colclough, Matthew B. Johnson, Matthew N. Wakeling, Nick D.L. Owens, Shenali A. Amaratunga, Sarah E. Flanagan, Kashyap A. Patel, Andrew T. Hattersley, Elisa De Franco, Mohamed Abdullah, Hessa Alkandari, Zehra Aycan, Semra Çetinkaya, Nancy Elbarbary, Radha Ghildiyal, Susana Gonzalez, Shaun Gorman, Samar Hassan, Savita Khadse, Jan Lebl, Jaida Manzoor, Nikhil Shah, Tara Hussein Tayeb, Alaa Al Assi, Arya Anil, Diego Balboa, Urvashi Chitnavis, Juliette Davis, Doga Eskier, Michael Imbeault, Santiago Morell, Sachin Muralidharan, Timo Otonkoski, Jonna Saarimäki-Vire   +34 more
doaj   +1 more source

Elevated serum aminotransferases in an infant with failure to thrive: A clinicopathological case report

JPGN Reports, EarlyView.
Jamie M. Klapp, Lauren Nichols, Nicholas J. Gloude, Amber Hildreth, Kathleen B. Schwarz   +4 more
wiley   +1 more source

Hydroxyl radical footprinting modification reveals an intradomain communication pathway in EFL1 disrupted by a Shwachman‐Diamond syndrome‐associated mutation

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Shwachman‐Diamond syndrome (SDS) is a rare genetic disorder characterized by pancreatic insufficiency and neutropenia. While most cases are linked to mutations in the SBDS gene, some involve mutations in the GTPase EFL1. This protein works with SBDS to release the anti‐association factor eIF6 from the 60S ribosomal subunit during ribosome ...
Jonathan A. Zúñiga‐Domínguez, Rohit Jain, Martín González‐Andrade, Erik R. Farquhar, Mark R. Chance, Abril Gijsbers, Nuria Sánchez‐Puig   +6 more
wiley   +1 more source

Exocrine pancreatic insufficiency (EPI) in canine

Logos Ciencia & Tecnología, 2013
Exocrine pancreatic insufficiency is a syndrome characterized by bad digestion and poor absorption result of the failure of the secretion of pancreatic enzymes and other substances that facilitate the absorption of dietary nutrients and certain vitamins ...
Camilo Guarín Patarroyo, Fabian Rodrigo Sánchez Cuervo   +1 more
doaj  

Institutional Outcomes following Total Pancreatectomy and Islet Autotransplantation in Children [PDF]

, 2018
Purpose: Total pancreatectomy with islet autotransplantation (TPIAT) is used to treat debilitating chronic pancreatitis (CP) and acute recurrent pancreatitis (ARP) that has failed medical and endoscopic therapy.
Sekoulopoulos, Stephen P
core   +1 more source

Survival After Pancreatic Resection for Intraductal Papillary Mucinous Neoplasm: Supporting Selective Surgery

United European Gastroenterology Journal, Volume 14, Issue 3, April 2026.
ABSTRACT Introduction Resection of intraductal papillary mucinous neoplasm (IPMN) aims to prevent progression to invasive pancreatic cancer. However, the risks of pancreatic surgery and frequent findings of low‐grade dysplasia (LGD) raise concerns about overtreatment.
Marcus Holmberg, Tomaso Dall'Olio, Mohamed Marwa, Carsten Palnaes Hansen, Dyre Berg Kleive, Gennaro Nappo, Lam Shi, Per Sandström, Dennis Björk, Parsa Hadesi, Raffaele Vincenzo De Rosa, Bodil Andersson, Daniel Ansari, Bhargava Chikkala, Letizia Todeschini, Charlotte Leseman, Job Schuitema, Yentl Lodewijks, Christopher Månsson, Spiros Delis, Frederik Berrevoet, Fabio Giannone, Sofia Xenaki, Elizabeth Pando, Claude Bertrand, Konstantinos Vasileiadis, Patrick Kirchweger, Calogero Ciulla, Claudio Luchini, Misha Luyer, Marc G. Besselink, Giovanni Marchegiani, Sanjay Pandanaboyana, Bobby Tingstedt, Laurent Sulpice, Johanna Wennerblom, Bergthor Björnsson, Anita Balakrishnan, Knut Jørgen Labori, Stefan Kobbelgaard Burgdorf, Motaz Qadan, Ernesto Sparrelid, Antonio Pea, Yasmin G. Hernandez‐Barco, Roberto Salvia, Poya Ghorbani   +45 more
wiley   +1 more source

Impact of Obesity on Pediatric Acute Recurrent and Chronic Pancreatitis [PDF]

, 2018
OBJECTIVE: The aim of this study was to assess the impact of obesity on pediatric acute recurrent pancreatitis or chronic pancreatitis (CP). METHODS: We determined body mass index (BMI) status at enrollment in INSPPIRE (INternational Study group ...
Abu-El-Haija, Maisam, Barth, Bradley, Bellin, Melena D., Fishman, Douglas S., Freedman, Steven D., Gariepy, Cheryl E., Giefer, Matthew J., Gonska, Tanja, Heyman, Melvin B., Himes, Ryan, Husain, Sohail Z., Lin, Tom K., Liu, Quin, Lowe, Mark E., McFerron, Brian A., Morinville, Veronique D., Ooi, Chee Y., Palermo, Joseph J., Perito, Emily R., Pohl, John F., Rhee, Sue, Schwarzenberg, Sarah Jane, Shah, Uzma, Troendle, David, Uc, Aliye, Werlin, Steven L., Wilschanski, Michael, Zimmerman, M. Bridget   +27 more
core   +1 more source

The Changing Landscape of Chronic Pancreatitis Research Trajectories Over Two Decades: A Global Meta‐Analysis Using MeSH Terms

United European Gastroenterology Journal, Volume 14, Issue 3, April 2026.
ABSTRACT Objectives Significant progress has been made in research on chronic pancreatitis (CP). It is essential to analyze recent trends in this field to guide future clinical investigations. Methods Publications related to CP research from 2000 to 2023 were retrieved from PubMed.
Ling‐Ying Jiang, Chao Wu, Kıvanç Görgülü, Yan‐Wei Lv, Hana Algül, Chao Han, Liang‐Hao Hu   +6 more
wiley   +1 more source

Effect of metformin on pancreatic neuroendocrine tumors of multiple endocrine neoplasia type 1

Journal of Neuroendocrinology, Volume 38, Issue 4, April 2026.
Abstract Metformin is a widely prescribed medication in the management of type 2 diabetes mellitus, and numerous epidemiological studies have indicated an association between metformin use and a reduced risk of certain cancers in diabetic populations. However, evidence supporting a role for metformin in cancer prevention remains inconclusive. Exploring
Serguei V. Kozlov, Sunita K. Agarwal, Theresa M. Guerin, Wendi Custer Lawrence, Laura L. Bassel, Akua Graf, Smita Jha, Lee S. Weinstein, Jenny E. Blau, Jaydira del Rivero   +9 more
wiley   +1 more source