Results 81 to 90 of about 314,408 (190)

A Systematic Review and Meta‐Analysis of Malnutrition and Metabolic Failure in High‐Potency Incretin Therapy

Obesity Science &Practice, Volume 12, Issue 5, October 2026.
ABSTRACT Objective High‐potency incretin therapy achieved substantial weight loss, but the extreme energy deficits it induced may obscure the underlying nutritional deterioration. This meta‐analysis synthesized data from 19 randomized trials across the SURMOUNT, STEP, SCALE, and OASIS programs to quantify the nutritional and body composition ...
Eugene Ampofo, Charles Apprey, Mary Amoako, Fiifi Derrick Turkson   +3 more
wiley   +1 more source

Exocrine Pancreatic Insufficiency Manifesting Before Insulin Dependence in Adult‐Onset Type 1 Diabetes

Clinical Case Reports
Exocrine pancreatic insufficiency may precede insulin dependence in adult‐onset type 1 diabetes. Unexplained steatorrhea or weight loss in people with diabetes warrants further investigations including imaging of abdomen/pancreas, exocrine pancreatic ...
Panagiotis Pavlou, Shrawan Pandit, Janaka Karalliedde   +2 more
doaj   +1 more source

Loss of function variants in the primate-specific gene ZNF808 cause neonatal, transient and adult-onset diabetesResearch in context

EBioMedicine
Summary: Background: Biallelic loss-of-function ZNF808 variants were recently identified as a cause of pancreatic agenesis characterised by insulin-treated permanent neonatal diabetes (PNDM), low birthweight and exocrine pancreatic insufficiency ...
James Russ-Silsby, Kevin Colclough, Matthew B. Johnson, Matthew N. Wakeling, Nick D.L. Owens, Shenali A. Amaratunga, Sarah E. Flanagan, Kashyap A. Patel, Andrew T. Hattersley, Elisa De Franco, Mohamed Abdullah, Hessa Alkandari, Zehra Aycan, Semra Çetinkaya, Nancy Elbarbary, Radha Ghildiyal, Susana Gonzalez, Shaun Gorman, Samar Hassan, Savita Khadse, Jan Lebl, Jaida Manzoor, Nikhil Shah, Tara Hussein Tayeb, Alaa Al Assi, Arya Anil, Diego Balboa, Urvashi Chitnavis, Juliette Davis, Doga Eskier, Michael Imbeault, Santiago Morell, Sachin Muralidharan, Timo Otonkoski, Jonna Saarimäki-Vire   +34 more
doaj   +1 more source

Treatment failure in celiac disease due to coexistent exocrine pancreatic insufficiency

, 1987
A 17-year-old white adolescent had a history of chronic diarrhea, delayed puberty, and growth failure. Investigations excluded cystic fibrosis, Shwachman syndrome, and endocrine causes of growth failure.
Weizman, Z., Cleghorn, G.J., Kopelman, H.R., Durie, P.R., Hamilton, J.R.   +4 more
core  

Natural History of Recurrent Acute Pancreatitis: Implications for Interventional Trial Design

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 7, Page 976-984, October 2026.
In this nationwide cohort of 6894 patients with recurrent acute pancreatitis, recurrence risk increased progressively with each episode and occurred most frequently within the first year. Successive episodes were separated by shorter intervals, indicating an accelerating disease course and highlighting the importance of early preventive interventions ...
Søren S. Olesen, Niels Henrik Bruun, Line Davidsen, Srdan Novovic, Stig B. Laursen, Enrique de‐Madaria, Dhiraj Yadav, Asbjørn M. Drewes   +7 more
wiley   +1 more source

Systematic Review of Exocrine Pancreatic Insufficiency after Gastrectomy for Cancer

, 2017
Background: Survival rates after a total gastrectomy with adequate lymphadenectomy are improving, leading to a shift in outcomes of interest from survival to postoperative outcomes and symptoms.
Straatman, Jennifer, Wiegel, Jim, Van Der Peet, Donald L., Jansma, E. P., Van Der Wielen, Nicole, Cuesta, Miguel A.   +5 more
core   +2 more sources

Review: pancreatic exocrine insufficiency in pancreatological diseases. [PDF]

Objective – to analyze, review and present evidence-based data on pancreatic exocrine insufficiency etiology, epidemiology, pathophysiology, symptoms, diagnosis, treatment in pancreatic diseases. Material and methods. During the preparation of the review
Klimavičiūtė, Ugnė,
core  

Pancreatic resections for advanced M1-pancreatic carcinoma : the value of synchronous metastasectomy [PDF]

, 2010
Background: For M1 pancreatic adenocarcinomas pancreatic resection is usually not indicated. However, in highly selected patients synchronous metastasectomy may be appropriate together with pancreatic resection when operative morbidity is low ...
Chromik, Ansgar Michael, M. H. Seelig, A. M. Chromik, Tannapfel, Andrea, Seelig, Mathias H., S. K. Seelig, Seelig, Stefanie Katharina, Burkert, Björn, Uhl, Waldemar, A. Tannapfel, B. Burkert, W. Uhl   +11 more
core   +1 more source

Vitamins and Chronic Wounds: How Altered Pharmacokinetics and Comorbidities Contribute to Vitamin Deficiencies

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
ABSTRACT Wound healing is complex and requires adequate amounts of macro‐ and micronutrients. When wound healing is delayed, a wound is considered chronic. Increasing evidence shows that vitamin deficiencies are prevalent in patients with chronic wounds, yet intervention studies with vitamin supplementation yielded inconsistent effects.
Michiel G. J. Balvers, Teuntje L. de Smit, Anne I. Slotegraaf, Remy H. H. Bemelmans, Joé L. P. Kolkert, Tim J. Schuijt, Renger F. Witkamp   +6 more
wiley   +1 more source

Spontaneous Hepatobiliary Disease in a Breeding Colony of Aotus spp.

Journal of Medical Primatology, Volume 55, Issue 5, October 2026.
ABSTRACT Background Owl monkeys are nonhuman primate species in the genus Aotus. The Michale E. Keeling Center for Comparative Medicine and Research maintains an Owl Monkey Breeding and Research Resource composed of four species of owl monkeys: Aotus nancymai, A. vociferans, A. azarae, and A. griseimembra.
M. E. Hensel, G. W. Wilkerson, L. Yan, C. L. Hodo, S. M. Kezar   +4 more
wiley   +1 more source