Results 101 to 110 of about 314,408 (190)

Rational Prescribing of Pancreatic Enzymes for Patients with Pancreatic Cancer

open access: yesPharmacy
Most patients with pancreatic cancer at some point present with symptoms related to exocrine pancreatic insufficiency (EPI). These include diarrhea, abdominal bloating, indigestion, steatorrhea, weight loss, and anorexia.
Mary Acelle G. Garcia   +3 more
doaj   +1 more source

Preoperative Glucose‐to‐Albumin Ratio as a Prognostic Marker for Survival in Pancreatic Cancer Patients Undergoing Pancreatectomy

open access: yesCancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Background Pancreatic cancer (PC) disrupts metabolic and nutritional processes, including glucose homeostasis and albumin levels. Both hyperglycemia and hypoalbuminemia have been linked to poorer outcomes in various cancers, including PC. This study investigates the preoperative glucose‐to‐albumin ratio (GAR) as a potential prognostic marker ...
Andrea Feci   +10 more
wiley   +1 more source

Negative impact of reduced exocrine pancreatic function on sarcopenia risk in the asymptomatic general population

open access: yesFrontiers in Nutrition
BackgroundIn patients with pancreatic disease, exocrine insufficiency facilitates sarcopenia. Here, we investigated whether impaired exocrine function in the asymptomatic general population is also associated with sarcopenia.MethodsWe pooled data from ...
Mats L. Wiese   +11 more
doaj   +1 more source

Pancreatic exocrine insufficiency after pancreatic surgery.

open access: yes, 2016
Pancreatic exocrine insufficiency is an often-underestimated complication following pancreatic surgery. After recent advances in managing acute postoperative complications the focus of current research is now shifting onto the long-term complications ...
Goess, Ruediger;Ceyhan, Güralp O;Friess, Helmut
core  

Lactoferrin and Nanotechnology: New Insights Into Glioblastoma Therapy

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Current glioblastoma multiforme (GBM) management primarily relies on surgery, chemotherapy, and radiotherapy; however, therapeutic efficacy remains limited due to tumor invasiveness and restricted drug penetration across the blood–brain barrier. Lactoferrin (LF), an iron‐binding glycoprotein with receptor‐mediated transport capability, has emerged as a
Atena Abed, Javad Amini Mahabadi
wiley   +1 more source

Type 5 Diabetes Mellitus: Pathophysiology, Clinical Phenotype, and Nutritional Management

open access: yesDiabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Type 5 Diabetes Mellitus (T5DM) is an emerging diabetes phenotype linked to chronic undernutrition. It predominantly affects young, lean individuals in low‐ and middle‐income countries. After its formal recognition by the International Diabetes Federation in 2025, T5DM resurfaced as a clinically relevant insulin‐deficient phenotype.
İrem Nur Şahin Anılgan   +1 more
wiley   +1 more source

Fatty pancreas disease in newly diagnosed type 2 diabetes patients: a case–control study on relationships with glycemic control and exocrine function

open access: yesDiabetology & Metabolic Syndrome
Background Fatty pancreas disease (FPD) is characterized by abnormal fat accumulation in pancreatic tissue and is often associated with obesity, metabolic syndrome, and type 2 diabetes mellitus (T2DM).
Tahsin Taner Karaevren   +13 more
doaj   +1 more source

Detection of Pancreatic Cancer via Specific Metabolite Markers: A Metabolomics Approach

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies worldwide because most patients are diagnosed at advanced stages when curative treatment is no longer feasible. Metabolomics has emerged as a promising strategy for identifying biochemical alterations associated with early tumor development ...
Mohammad Javad Roustaye Gourabi   +8 more
wiley   +1 more source

COMPARING THE ENZYME REPLACEMENT THERAPY COST IN POST PANCREATECTOMY PATIENTS DUE TO PANCREATIC TUMOR AND CHRONIC PANCREATITIS

open access: yesArquivos de Gastroenterologia
Background - Among late postoperative complications of pancreatectomy are the exocrine and endocrine pancreatic insufficiencies. The presence of exocrine pancreatic insufficiency imposes, as standard treatment, pancreatic enzyme replacement.
Anna Victoria FRAGOSO   +3 more
doaj   +1 more source

Inhibition Effect of Pancreatic Exocrine Insufficiency on Immune Checkpoint Inhibitor Treatment in Pancreatic Cancer: A Retrospective Study

open access: yes
Qiankun Luo,1,* Yifei Dong,1,* Pan Liu,1,* Chao He,2 Lei Chen,1 Kailun Zhang,1 Changjie Pan,1 Yahui Gao,1 Tao Qin1 1Department of Hepatobiliary and Pancreatic Surgery, Zhengzhou University People’s Hospital, Henan Provincial People’s Hospital,
Luo Q   +8 more
core  

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