Results 1 to 10 of about 19,582 (145)

Pancreatic Enzyme Replacement Therapy in Pancreatic Cancer [PDF]

Cancers, 2020
Pancreatic cancer is an aggressive malignancy and the seventh leading cause of global cancer deaths in industrialised countries. More than 80% of patients suffer from significant weight loss at diagnosis and over time tend to develop severe cachexia. A major cause of weight loss is malnutrition. Patients may experience pancreatic exocrine insufficiency
Massimo Falconi, Pezzilli R, Gabriele Capurso   +2 more
exaly   +5 more sources

Pancreatic Enzyme Replacement Therapy in Patients Undergoing First-Line Gemcitabine Plus nab-paclitaxel for Advanced Pancreatic Adenocarcinoma [PDF]

Frontiers in Oncology, 2021
BackgroundThe clinical consequences of pancreatic exocrine insufficiency and its treatment in advanced pancreatic ductal adenocarcinoma (PDAC) are poorly investigated.
Ilaria Trestini, Luisa Carbognin, Luisa Carbognin, Umberto Peretti, Isabella Sperduti, Alberto Caldart, Daniela Tregnago, Alice Avancini, Alessandra Auriemma, Giulia Orsi, Sara Pilotto, Luca Frulloni, Gabriele Capurso, Emilio Bria, Michele Reni, Giampaolo Tortora, Michele Milella   +16 more
doaj   +4 more sources

Enzyme replacement therapy for pancreatic insufficiency: present and future

Clinical and Experimental Gastroenterology, 2011
Aaron Fieker1, Jessica Philpott1, Martine Armand21Division of Digestive Diseases, University of Oklahoma, OKC, OK, USA; 2INSERM, U476 "Nutrition Humaine et Lipides", Marseille, F-13385 France; Univ Méditerranée Aix-
Fieker A, Philpott J, Arm, M
doaj   +7 more sources

The effectiveness of pancreatic enzyme replacement therapy for malabsorption in advanced pancreatic cancer, a pilot study [PDF]

Palliative Care, 2019
Advanced adenocarcinoma of the pancreas has a globally poor prognosis. One of the characteristic features of pancreatic cancer (PC) is pancreatic exocrine insufficiency (PEI).
Amanda Landers, Helen Brown, Matthew Strother   +2 more
doaj   +3 more sources

Pancreatic Enzyme Replacement Therapy in Cystic Fibrosis. [PDF]

Nutrients, 2022
While typically considered a pulmonary disease, cystic fibrosis patients develop significant nutritional complications and comorbidities, especially those who are pancreatic insufficient. Clinicians must have a high suspicion for cystic fibrosis among patients with clinical symptoms of pancreatic insufficiency, and pancreatic enzymatic replacement ...
Freswick PN, Reid EK, Mascarenhas MR.
europepmc   +3 more sources

Gut microbiome as a response marker for pancreatic enzyme replacement therapy in a porcine model of exocrine pancreas insufficiency [PDF]

Microbial Cell Factories, 2020
Background Exocrine pancreatic insufficiency (EPI) is characterized by the loss of active pancreatic enzymes and a resulting severely reduced food digestion. EPI therapy requires orally applied pancreatic enzyme replacement. The gut microbiome is a known
Sabrina Ritz, Daniela Hahn, Haleluya T. Wami, Karin Tegelkamp, Ulrich Dobrindt, Juergen Schnekenburger   +5 more
doaj   +2 more sources

Pancreatic enzyme replacement therapy can improve infection level nutrition condition and prognosis of patients with sepsis [PDF]

Food & Nutrition Research
Objective: This study aimed to investigate the effects of pancreatic enzyme replacement therapy (PERT) on infection level, nutrition condition and prognosis of patients with sepsis.
Li Zhao, Sheng Wang
doaj   +2 more sources

Timing of pancreatic enzyme replacement therapy (PERT) in cystic fibrosis. [PDF]

Cochrane Database Syst Rev, 2021
Cystic fibrosis (CF) is an autosomal recessive, life-limiting, multisystem disease affecting over 70,000 individuals worldwide. Between 80% and 90% of people with CF suffer with pancreatic exocrine insufficiency, which if left untreated, leads to a poor nutritional status.
Ng C, Major G, Smyth AR.
europepmc   +3 more sources

Quality of Life Assessment after Pancreatic Enzyme Replacement Therapy in Chronic Pancreatitis [PDF]

Canadian Journal of Gastroenterology, 2003
GOALS: To evaluate the quality of life (QoL) of patients with chronic pancreatitis before and after pancreatic enzyme replacement therapy in a prospective, multicentre, follow-up study.
László Czakó, Tamás Takács, Peter Hegyi, László Prónai, Zsolt Tulassay, Lilla Lakner, Zoltán Döbrönte, Krisztina Boda, János Lonovics   +8 more
doaj   +3 more sources

Pancreatic enzyme replacement therapy for people with cystic fibrosis. [PDF]

Cochrane Database Syst Rev, 2016
Most people with cystic fibrosis (80% to 90%) need pancreatic enzyme replacement therapy to prevent malnutrition. Enzyme preparations need to be taken whenever food is taken, and the dose needs to be adjusted according to the food consumed. A systematic review on the efficacy and safety of pancreatic enzyme replacement therapy is needed to guide ...
Somaraju UR, Solis-Moya A.
europepmc   +7 more sources