Enzyme replacement therapy for pancreatic insufficiency: present and future
Aaron Fieker1, Jessica Philpott1, Martine Armand21Division of Digestive Diseases, University of Oklahoma, OKC, OK, USA; 2INSERM, U476 "Nutrition Humaine et Lipides", Marseille, F-13385 France; Univ Méditerranée Aix-
Fieker A, Philpott J, Arm, M
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Pancreatic Enzyme Replacement Therapy in Pancreatic Cancer. [PDF]
Pancreatic cancer is an aggressive malignancy and the seventh leading cause of global cancer deaths in industrialised countries. More than 80% of patients suffer from significant weight loss at diagnosis and over time tend to develop severe cachexia. A major cause of weight loss is malnutrition. Patients may experience pancreatic exocrine insufficiency
Pezzilli R +5 more
europepmc +5 more sources
The effectiveness of pancreatic enzyme replacement therapy for malabsorption in advanced pancreatic cancer, a pilot study [PDF]
Advanced adenocarcinoma of the pancreas has a globally poor prognosis. One of the characteristic features of pancreatic cancer (PC) is pancreatic exocrine insufficiency (PEI).
Amanda Landers +2 more
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Pancreatic Enzyme Replacement Therapy in Patients Undergoing First-Line Gemcitabine Plus nab-paclitaxel for Advanced Pancreatic Adenocarcinoma [PDF]
BackgroundThe clinical consequences of pancreatic exocrine insufficiency and its treatment in advanced pancreatic ductal adenocarcinoma (PDAC) are poorly investigated.
Ilaria Trestini +16 more
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Gut microbiome as a response marker for pancreatic enzyme replacement therapy in a porcine model of exocrine pancreas insufficiency [PDF]
Background Exocrine pancreatic insufficiency (EPI) is characterized by the loss of active pancreatic enzymes and a resulting severely reduced food digestion. EPI therapy requires orally applied pancreatic enzyme replacement. The gut microbiome is a known
Sabrina Ritz +5 more
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Pancreatic enzyme replacement therapy can improve infection level nutrition condition and prognosis of patients with sepsis [PDF]
Objective: This study aimed to investigate the effects of pancreatic enzyme replacement therapy (PERT) on infection level, nutrition condition and prognosis of patients with sepsis.
Li Zhao, Sheng Wang
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Pancreatic enzyme replacement therapy in subjects with exocrine pancreatic insufficiency and diabetes mellitus: a real-life, case–control study [PDF]
Background Exocrine pancreatic insufficiency (EPI) can be associated with all types of diabetes. Pancreatic enzyme replacement therapy (PERT) has short and long-term benefits in subjects with EPI, but its effects on diabetes control are uncertain.
Laure Alexandre-Heymann +4 more
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Survey of Pancreatic Enzyme Replacement Therapy Dosing Experiences in Adults with Exocrine Pancreatic Insufficiency. [PDF]
Lewis DM, Shahid A.
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Hospitalization rates among patients with cystic fibrosis using pancreatic enzyme replacement therapy. [PDF]
Trapnell BC +5 more
europepmc +2 more sources
This review presents current updates of pancreatic enzyme replacement therapy in children with cystic fibrosis based on literature published in the last decade and some special considerations regarding pancreatic enzyme replacement therapy in the era of ...
Mirela-Elena Ritivoiu +7 more
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