Results 91 to 100 of about 167,613 (264)

The light chain but not the heavy chain of botulinum A toxin inhibits exocytosis from permeabilized adrenal chromaffin cells [PDF]

open access: yes, 1989
The heavy and light chains of botulinum A toxin were separated by anion exchange chromatography. Their intracellular actions were studied using bovine adrenal chromaffin cells permeabilized with streptolysin O.
Ahnert-Hilger, G.   +4 more
core   +1 more source

Exocytosis of the silicified cell wall of diatoms involves extensive membrane disintegration

open access: yesNature Communications, 2023
Exocytosis is a fundamental cellular process. Here, the authors report an unusual exocytosis mechanism in the silicified cell wall of diatoms, in which membrane patches are discarded.
Diede de Haan   +8 more
doaj   +1 more source

Annexin A2–dependent actin bundling promotes secretory granule docking to the plasma membrane and exocytosis

open access: yesJournal of Cell Biology, 2015
Annexin A2 and the actin cytoskeleton are essential partners in providing lipid platforms for granule recruitment and fusion during exocytosis.
M. Gabel   +7 more
semanticscholar   +1 more source

Septin Dynamics Are Essential for Exocytosis*

open access: yesJournal of Biological Chemistry, 2015
Background: Septins serve as scaffolds for membrane-associated protein complexes. Results: Knockdown of septin-2 or disruption of septin assembly/disassembly impairs interactions between exocytic proteins and inhibits late steps of exocytosis. Conclusion:
E. Tokhtaeva   +10 more
semanticscholar   +1 more source

Regulation of plasma membrane expansion during axon formation [PDF]

open access: yes, 2018
Here, will review current evidence regarding the signaling pathways and mechanisms underlying membrane addition at sites of active growth during axon formation.Fil: Quiroga, Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas.
Bisbal, Mariano   +2 more
core   +1 more source

Synaptic vesicle exocytosis captured by quick freezing and correlated with quantal transmitter release

open access: yesJournal of Cell Biology, 1979
We describe the design and operation of a machine that freezes biological tissues by contact with a cold metal block, which incorporates a timing circuit that stimulates frog neuromuscular junctions in the last few milliseconds before thay are frozen. We
J. Heuser   +5 more
semanticscholar   +1 more source

Both electrical and metabolic coupling shape the collective multimodal activity and functional connectivity patterns in beta cell collectives: A computational model perspective [PDF]

open access: yesarXiv, 2023
Pancreatic beta cells are coupled excitable oscillators that synchronize their activity via different communication pathways. Their oscillatory activity manifests itself on multiple timescales and consists of bursting electrical activity, subsequent oscillations in the intracellular Ca2+, as well as oscillations in metabolism and exocytosis.
arxiv  

Sustained exocytosis after action potential-like stimulation at low frequencies in mouse chromaffin cells depends on a dynamin-dependent fast endocytotic process [PDF]

open access: yes, 2016
Under basal conditions the action potential firing rate of adrenal chromaffin cells is lower than 0.5 Hz. The maintenance of the secretory response at such frequencies requires a continuous replenishment of releasable vesicles.
Alvarez, Yanina Daniela   +7 more
core   +1 more source

HIV-1 gp120 Promotes Lysosomal Exocytosis in Human Schwann Cells

open access: yesFrontiers in Cellular Neuroscience, 2019
Human immunodeficiency virus type 1 (HIV-1) associated neuropathy is the most common neurological complication of HIV-1, with debilitating pain affecting the quality of life.
Gaurav Datta   +4 more
doaj   +1 more source

Exocytosis of ATP From Astrocytes Modulates Phasic and Tonic Inhibition in the Neocortex

open access: yesPLoS Biology, 2014
Astrocytes secrete ATP by exocytosis from synaptic-like vesicles, activating neuronal P2X receptors, which contribute to postsynaptic GABA receptor down-regulation, ultimately mediating the communication between astrocytes and neurons required for brain ...
U. Lalo   +5 more
semanticscholar   +1 more source

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