Results 81 to 90 of about 151,391 (333)

Synchrotron XRF Imaging Reveals Manganese Accumulation in the Golgi and Post‐Synapses of Neurons and Enhanced Uptake in Astrocytes

open access: yesAdvanced Science, EarlyView.
Despite widespread exposure, the mechanisms of manganese neurotoxicity remain poorly understood. Using correlative cryogenic fluorescence and synchrotron X‐ray fluorescence imaging techniques, we show that the Golgi apparatus is the primary accumulation site for manganese in both neurons and astrocytes, and that manganese targets the neuronal ...
Ines Kelkoul   +12 more
wiley   +1 more source

Exocytosis of the silicified cell wall of diatoms involves extensive membrane disintegration

open access: yesNature Communications, 2023
Exocytosis is a fundamental cellular process. Here, the authors report an unusual exocytosis mechanism in the silicified cell wall of diatoms, in which membrane patches are discarded.
Diede de Haan   +8 more
doaj   +1 more source

Ecological Adaptation Mechanisms Underlying Successful Plant Reproduction

open access: yesAdvanced Science, EarlyView.
During floral induction, various environmental and endogenous signals converge to regulate the florigen protein, which is transported from leaves to the SAM to initiate flowering. Within the SAM, a complex network of receptor kinases and small peptides orchestrates floral development with high spatiotemporal precision.
Hang Zhao   +8 more
wiley   +1 more source

A Novel Anti-Inflammatory Effect for High Density Lipoprotein.

open access: yesPLoS ONE, 2015
High density lipoprotein has anti-inflammatory effects in addition to mediating reverse cholesterol transport. While many of the chronic anti-inflammatory effects of high density lipoprotein (HDL) are attributed to changes in cell adhesion molecules ...
Scott J Cameron   +5 more
doaj   +1 more source

Experimental measurement of endocytosis in fungal hyphae. [PDF]

open access: yes, 2018
The present study examines the notion that polarized exocytosis in the tips of growing hyphae creates an excess of plasma membrane and thus the need for its removal by endocytosis.
Bartnicki-Garcia, Salomon   +3 more
core  

Molecular medicine of microRNAs: structure, function and implications for diabetes [PDF]

open access: yes, 2008
MicroRNAs (miRNAs) are a family of endogenous small noncoding RNA molecules, of 19–28 nucleotides in length. In humans, up to 3% of all genes are estimated to encode these evolutionarily conserved sequences.
Duncan   +5 more
core   +1 more source

Postsynaptic Complexin Mediates Constitutive Exocytosis of Nicotinic Acetylcholine Receptor

open access: yesAdvanced Science, EarlyView.
Beyond its established presynaptic role, complexin is identified as a postsynaptic regulator of neurotransmitter receptor trafficking. By promoting constitutive and activity‐dependent exocytosis of nicotinic acetylcholine receptors, complexin controls spontaneous synaptic signaling at the C.
Ya Wang   +4 more
wiley   +1 more source

HIV-1 gp120 Promotes Lysosomal Exocytosis in Human Schwann Cells

open access: yesFrontiers in Cellular Neuroscience, 2019
Human immunodeficiency virus type 1 (HIV-1) associated neuropathy is the most common neurological complication of HIV-1, with debilitating pain affecting the quality of life.
Gaurav Datta   +4 more
doaj   +1 more source

Exocytosis and Endocytosis: Yin-Yang Crosstalk for Sculpting a Dynamic Growing Pollen Tube Tip

open access: yesFrontiers in Plant Science, 2020
The growing pollen tube has become one of the most fascinating model cell systems for investigations into cell polarity and polar cell growth in plants.
Lifeng Zhao   +2 more
doaj   +1 more source

Regulation of plasma membrane expansion during axon formation [PDF]

open access: yes, 2018
Here, will review current evidence regarding the signaling pathways and mechanisms underlying membrane addition at sites of active growth during axon formation.Fil: Quiroga, Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas.
Bisbal, Mariano   +2 more
core   +1 more source

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