Results 61 to 70 of about 21,092 (247)
G-Protein Coupled Receptor-Evoked Glutamate Exocytosis from Astrocytes: Role of Prostaglandins
Neural Plasticity, 2014 Astrocytes are highly secretory cells, participating in rapid brain communication by releasing glutamate. Recent evidences have suggested that this process is largely mediated by Ca2+-dependent regulated exocytosis of VGLUT-positive vesicles.
Corrado Cali +4 more
doaj +1 more source
Regional and developmental brain expression patterns of SNAP25 splice variants [PDF]
, 2011 SNAP25 is an essential SNARE protein for regulated exocytosis in neuronal cells. Differential splicing of the SNAP25 gene results in the expression of two transcripts, SNAP25a and SNAP25b.
Chamberlain, Luke H. +7 more
core +1 more source
Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Advanced Science, EarlyView.Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
Respiratory Research, 2010 Background Perfluorocarbons (PFC) are used to improve gas exchange in diseased lungs. PFC have been shown to affect various cell types. Thus, effects on alveolar type II (ATII) cells and surfactant metabolism can be expected, data, however, are ...
Ravasio Andrea +5 more
doaj +1 more source
Permeabilized Parotid Acini : A New Approach to Amylase Exocytosis [PDF]
, 1991 P(論文)Permeabilized cells enabled us to gain access to the intracellular milieu required for exocytosis. Various permeabilization techniques have been applied to many secretory cells including pancreatic acini, however, studies with permeabilized salivary
田隈, 泰信 +3 more
core
VAMP8 mucin exocytosis attenuates intestinal pathogenesis by Entamoeba histolytica
, 2017 The intestinal mucosa encounters a barrage of ingested insults within the host yet under homeostasis elegantly facilitates nutrient absorption and sustenance of the commensal microbiota. An essential defence mechanism employed by the host is limiting the
Steve Cornick +3 more
core +1 more source
Artificial Cells for Dissecting Exocytosis
, 2023 The fusion of vesicles and exocytosis release of neurotransmitters into the extracellular space for detection and chemical signal decoding by neighboring cells is the key process in neuronal communication.
Cans, Ann-Sofie, +3 more
core +1 more source
Charting Endocrine Progenitors Across Species and Organs
Advanced Science, EarlyView.Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing +21 more
wiley +1 more source
Exocytosis in Type 2 Diabetes- Functional and genetic studies of hormone secretion [PDF]
, 2012 Type 2 Diabetes (T2D) is characterized by dysregulated beta-and alpha-cell hormone secretion leading to elevated blood glucose levels. Several proteins are crucial in maintaining exocytosis of the hormone-containing granules such as Syntaxin1A (Stx1A ...
Andersson, Sofia A
core
Estrogen activates endothelial exocytosis
, 2021 Estrogen replacement for post-menopausal women has been proven beneficial and widely used in treating post-menopausal symptoms such as hot flush, vaginal dryness and osteoporosis. However, its cardiovascular benefit is still controversial.
Lowenstein, Charles J. +5 more
core +1 more source