Results 51 to 60 of about 99,750 (290)
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Bafilomycin A1, a vacuolar H+-ATPase inhibitor, and botulinum toxin B and tetanus toxin, both vesicle fusion inhibitors, are widely known exocytosis blockers that have been used to inhibit the presynaptic release of neurotransmitters.
Dong Ho Woo +4 more
doaj +1 more source
Human pancreatic islet miRNA-mRNA networks of altered miRNAs due to glycemic status
Summary: MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression via mRNA targeting, playing important roles in the pancreatic islets. We aimed to identify molecular pathways and genomic regulatory regions associated with altered miRNA
Alexandros Karagiannopoulos +5 more
doaj +1 more source
Life‐Like Ferrous Oxide Microspheres from Kombucha
Kombucha bacterial cellulose, sodium alginate, and ferrous nitrate self‐assemble into membrane‐enclosed iron oxide microspheres. These microspheres bud daughter vesicles, sustain 24‐h electrochemical oscillations, and filter theta‐band signals.
Panagiotis Mougkogiannis +2 more
wiley +1 more source
tPA‐GFP is a reliable probe for detecting compound exocytosis in human pancreatic β‐cells
Pancreatic β‐cells secrete insulin stored in large dense core vesicles (LDCV) by fusion of vesicle and plasma membrane during a process called insulin exocytosis.
Aishwarya A. Makam +5 more
doaj +1 more source
Background Subjects born with low birth weight (LBW) display a more energy-conserving response to fasting compared with normal birth weight (NBW) subjects.
Line Hjort +7 more
doaj +1 more source
An isoform-specific function of Cdc42 in regulating mammalian Exo70 during axon formation
The brain-specific isoform of the GTPase Cdc42 is shown to promote axon formation by interacting with the exocyst tethering complex and increasing exocytosis downstream of its activator Arhgef7. The highly conserved GTPase Cdc42 is an essential regulator
Priyadarshini Ravindran +1 more
doaj +1 more source
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang +18 more
wiley +1 more source
Lytic granule exocytosis at immune synapses: lessons from neuronal synapses
Regulated exocytosis is a central mechanism of cellular communication. It is not only the basis for neurotransmission and hormone release, but also plays an important role in the immune system for the release of cytokines and cytotoxic molecules.
Hsin-Fang Chang +4 more
doaj +1 more source
The Mechanisms of Exocytosis Studied in Cells and Models with Amperometry [PDF]
Exocytosis is the universal basis for neuronal communication, allowing the controlled release of neurotransmitter molecules from the presynaptic cell. Exocytosis has been widely studied in many systems.
Mellander, Lisa
core +1 more source

