Results 1 to 10 of about 164 (63)

Thermodynamic Efficiency of Somatic Exocytosis of Serotonin [PDF]

open access: yesFrontiers in Physiology, 2019
Through somatic exocytosis neurons liberate immense amounts of transmitter molecules that modulate the functioning of the nervous system. A stream of action potentials triggers an ATP-dependent transport of transmitter-containing vesicles to the plasma ...
J M Rubi   +2 more
exaly   +11 more sources

The Dynamics of Somatic Exocytosis in Monoaminergic Neurons [PDF]

open access: yesFrontiers in Physiology, 2012
Some monoaminergic neurons can release neurotransmitters by exocytosis from their cell bodies. The amount of monoamine released by somatic exocytosis can be comparable to that released by synaptic exocytosis, though neither the underlying mechanisms nor ...
Bidyut Sarkar   +2 more
exaly   +7 more sources

Cycling of Dense Core Vesicles Involved in Somatic Exocytosis of Serotonin by Leech Neurons [PDF]

open access: yesFrontiers in Physiology, 2012
We studied the cycling of dense core vesicles producing somatic exocytosis of serotonin. Our experiments were made using electron microscopy and vesicle staining with fluorescent dye FM1-43 in Retzius neurons of the leech, which secrete serotonin from ...
Citlali Trueta, FRANCISCO F De-Miguel
exaly   +6 more sources

Exocytosis of serotonin from the neuronal soma is sustained by a serotonin and calcium-dependent feedback loop

open access: yesFrontiers in Cellular Neuroscience, 2014
The soma of many neurons releases large amounts of transmitter molecules through an exocytosis process that continues for hundreds of seconds after the end of the triggering stimulus.
Citlali Trueta   +2 more
exaly   +4 more sources

Action potential‐triggered somatic exocytosis in mesencephalic trigeminal nucleus neurons in rat brain slices [PDF]

open access: yesJournal of Physiology, 2012
Non‐technical summary  Ca2+‐regulated axon terminal exocytosis is essential for neuronal communication in the CNS. Besides, the somata may also undergo Ca2+‐dependent exocytosis in some neurons in the brain. In the present work we recorded activity/Ca2+‐dependent secretion in somata of the mesencephalic trigeminal nucleus (MeV).
Hong-Ping Huang   +2 more
exaly   +7 more sources

A high spatiotemporal study of somatic exocytosis with scanning electrochemical microscopy and nanoITIES electrodes

open access: yesChemical Science, 2018
Extra-synaptic exocytosis is an essential component of cellular communication. A knowledge gap exists in the exocytosis of the non-redox active transmitter acetylcholine. Using the nano-interface between two immiscible electrolyte solutions and scanning electrochemical microscopy, a high resolution spatiotemporal study of acetylcholine exocytosis is ...
Theresa M Welle   +2 more
exaly   +5 more sources

Extrasynaptic exocytosis and its mechanisms: a source of molecules mediating volume transmission in the nervous system

open access: yesFrontiers in Physiology, 2012
We review the evidence of exocytosis from extrasynaptic sites in the soma, dendrites and axonal varicosities of central and peripheral neurons of vertebrates and invertebrates, and how it may contribute to signaling in the nervous system.
Citlali Trueta, FRANCISCO F De-Miguel
exaly   +4 more sources

Extrasynaptic Neurotransmission Mediated by Exocytosis and Diffusive Release of Transmitter Substances

open access: yesFrontiers in Synaptic Neuroscience, 2018
This review article deals with the mechanisms of extrasynaptic release of transmitter substances, namely the release from the soma, axon and dendrites in the absence of postsynaptic counterparts.
Elaine Del-Bel   +2 more
exaly   +4 more sources

Somatic Exocytosis of Serotonin Mediated by L‐Type Calcium Channels in Cultured Leech Neurones

open access: yesJournal of Physiology, 2003
We studied somatic exocytosis of serotonin and its mediation by L‐type calcium (Ca2+) channels in cultured Retzius neurones of the leech. Exocytosis was induced by trains of impulses at different frequencies or by depolarisation with 40 mm potassium (K+), and was quantified by use of the fluorescent dye FM 1–43.
Citlali Trueta, FRANCISCO F De-Miguel
exaly   +5 more sources

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