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Biology of reproduction, 2011
The molecular basis underlying the binding of spermatozoa to their homologous eggs and the subsequent induction of acrosomal exocytosis remain a major unresolved issue in mammalian fertilization. Novel cell adhesion systems are now being explored to advance this research.
Gary F, Clark +4 more
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The molecular basis underlying the binding of spermatozoa to their homologous eggs and the subsequent induction of acrosomal exocytosis remain a major unresolved issue in mammalian fertilization. Novel cell adhesion systems are now being explored to advance this research.
Gary F, Clark +4 more
openaire +1 more source
<p>The Priming Factor CAPS, Mediates Somatic Exocytosis of Serotonin</p>
The role of the vesicle priming factor CAPS (calcium-dependent activator protein for secretion) in somatic exocytosis was studied in the large serotonergic Retzius neuron of the leech. Increased electrical activity prompts Retzius neurons to release serotonin en masse from somatic dense core vesicles (DCVs). This exocytosis is evoked by calcium releaseJose Arturo Laguna +4 more
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The dynamics of somatic exocytosis in monoaminergic neurons [PDF]
Some monoaminergic neurons can release neurotransmitters by exocytosis from their cell bodies. The amount of monoamine released by somatic exocytosis can be comparable to that released by synaptic exocytosis, though neither the underlying mechanisms nor ...
Bidyut eSarkar +6 more
doaj +5 more sources
Thermodynamic Efficiency of Somatic Exocytosis of Serotonin [PDF]
Through somatic exocytosis neurons liberate immense amounts of transmitter molecules that modulate the functioning of the nervous system. A stream of action potentials triggers an ATP-dependent transport of transmitter-containing vesicles to the plasma ...
Paula Noguez +2 more
doaj +7 more sources
Cycling of dense core vesicles involved in somatic exocytosis of serotonin by leech neurons [PDF]
We studied the cycling of dense core vesicles producing somatic exocytosis of serotonin. Our experiments were made using electron microscopy and vesicle staining with fluorescent dye FM1-43 in Retzius neurons of the leech, which secrete serotonin from ...
Citlali eTrueta +2 more
doaj +5 more sources
A high spatiotemporal study of somatic exocytosis with scanning electrochemical microscopy and nanoITIES electrodes. [PDF]
Extra-synaptic exocytosis is an essential component of cellular communication. A knowledge gap exists in the exocytosis of the non-redox active transmitter acetylcholine. Using the nano-interface between two immiscible electrolyte solutions and scanning electrochemical microscopy, a high resolution spatiotemporal study of acetylcholine exocytosis is ...
Welle TM +4 more
europepmc +6 more sources
Action potential‐triggered somatic exocytosis in mesencephalic trigeminal nucleus neurons in rat brain slices [PDF]
Non‐technical summary Ca2+‐regulated axon terminal exocytosis is essential for neuronal communication in the CNS. Besides, the somata may also undergo Ca2+‐dependent exocytosis in some neurons in the brain. In the present work we recorded activity/Ca2+‐dependent secretion in somata of the mesencephalic trigeminal nucleus (MeV).
Bo, Zhang +15 more
exaly +6 more sources
Somatic Exocytosis of Serotonin Mediated by L‐Type Calcium Channels in Cultured Leech Neurones
We studied somatic exocytosis of serotonin and its mediation by L‐type calcium (Ca2+) channels in cultured Retzius neurones of the leech. Exocytosis was induced by trains of impulses at different frequencies or by depolarisation with 40 mm potassium (K+), and was quantified by use of the fluorescent dye FM 1–43.
Citlali, Trueta +2 more
openaire +5 more sources
The proteostatic landscape of healthy human oocytes [PDF]
Oocytes, female germ cells that develop into eggs, are among the longest-lived cells in the animal body. Recent studies on mouse oocytes highlight unique adaptations in protein homeostasis (proteostasis) within these cells.
Gabriele Zaffagnini +4 more
doaj +2 more sources

