The dynamics of somatic exocytosis in monoaminergic neurons [PDF]
Frontiers in Physiology, 2012 Some monoaminergic neurons can release neurotransmitters by exocytosis from their cell bodies. The amount of monoamine released by somatic exocytosis can be comparable to that released by synaptic exocytosis, though neither the underlying mechanisms nor ...
Bidyut eSarkar +6 more
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Thermodynamic Efficiency of Somatic Exocytosis of Serotonin [PDF]
Frontiers in Physiology, 2019 Through somatic exocytosis neurons liberate immense amounts of transmitter molecules that modulate the functioning of the nervous system. A stream of action potentials triggers an ATP-dependent transport of transmitter-containing vesicles to the plasma ...
Paula Noguez +2 more
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Cycling of dense core vesicles involved in somatic exocytosis of serotonin by leech neurons [PDF]
Frontiers in Physiology, 2012 We studied the cycling of dense core vesicles producing somatic exocytosis of serotonin. Our experiments were made using electron microscopy and vesicle staining with fluorescent dye FM1-43 in Retzius neurons of the leech, which secrete serotonin from ...
Citlali eTrueta +2 more
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A high spatiotemporal study of somatic exocytosis with scanning electrochemical microscopy and nanoITIES electrodes. [PDF]
Chem Sci, 2018 Extra-synaptic exocytosis is an essential component of cellular communication. A knowledge gap exists in the exocytosis of the non-redox active transmitter acetylcholine. Using the nano-interface between two immiscible electrolyte solutions and scanning electrochemical microscopy, a high resolution spatiotemporal study of acetylcholine exocytosis is ...
Welle TM +4 more
europepmc +7 more sources
Somatic Exocytosis of Serotonin Mediated by L‐Type Calcium Channels in Cultured Leech Neurones
The Journal of Physiology, 2003 We studied somatic exocytosis of serotonin and its mediation by L‐type calcium (Ca2+) channels in cultured Retzius neurones of the leech. Exocytosis was induced by trains of impulses at different frequencies or by depolarisation with 40 mm potassium (K+), and was quantified by use of the fluorescent dye FM 1–43.
Citlali Trueta +2 more
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Action potential‐triggered somatic exocytosis in mesencephalic trigeminal nucleus neurons in rat brain slices [PDF]
The Journal of Physiology, 2011 Non‐technical summary Ca2+‐regulated axon terminal exocytosis is essential for neuronal communication in the CNS. Besides, the somata may also undergo Ca2+‐dependent exocytosis in some neurons in the brain. In the present work we recorded activity/Ca2+‐dependent secretion in somata of the mesencephalic trigeminal nucleus (MeV).
Bo Zhang +15 more
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Acetylcholine as a trigger of the somatic exocytosis in Retzius neurons [PDF]
, 2020 AbstractThe redistribution of vesicles containing serotonin in leech neurons was studied using the fluorescent, scanning ion-conductance, and laser phase microscopy methods. During acetylcholine receptor (AChR) activation in Retzius neurons, the changes of Ca2+desorption, cellular stiffness and the cell optical phase difference (OPD) were established ...
Т. А. Казакова +4 more
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Action Potential-Triggered Somatic Exocytosis in Mesencephalic Trigeminal Nucleus Neurons in Rat Brain Slices [PDF]
Biophysical Journal, 2012 The neurons in the mesencephalic trigeminal nucleus (MeV) play essential roles in proprioceptive sensation of the face and oral cavity. The somata of MeV neurons are generally assumed to carry out neuronal functions but not to play a direct role in synaptic transmission.
Bo Zhang +12 more
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The proteostatic landscape of healthy human oocytes [PDF]
The EMBO JournalOocytes, female germ cells that develop into eggs, are among the longest-lived cells in the animal body. Recent studies on mouse oocytes highlight unique adaptations in protein homeostasis (proteostasis) within these cells.
Gabriele Zaffagnini +4 more
doaj +2 more sources
Carbohydrate-Mediated Binding and Induction of Acrosomal Exocytosis in a Boar Sperm-Somatic Cell Adhesion Model1 [PDF]
Biology of Reproduction, 2010 Gary F. Clark +4 more
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