Activity-dependent release of Adenosine: a critical re-evaluation of mechanism [PDF]
, 2008 Adenosine is perhaps the most important and universal modulator in the brain. The current consensus is that it is primarily produced in the extracellular space from the breakdown of previously released ATP.
Wall, Mark J., Dale, Nicholas
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Current status and future directions of botulinum neurotoxins for targeting pain processing. [PDF]
, 2015 Current evidence suggests that botulinum neurotoxins (BoNTs) A1 and B1, given locally into peripheral tissues such as skin, muscles, and joints, alter nociceptive processing otherwise initiated by inflammation or nerve injury in animal models and humans.
Pellett, Sabine +2 more
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Synaptotagmin 1 oligomers clamp and regulate different modes of neurotransmitter release [PDF]
, 2020 Release of neurotransmitters relies on submillisecond coupling of synaptic vesicle fusion to the triggering signal: AP-evoked presynaptic Ca2+ influx.
Bello, Oscar D. +9 more
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Frontiers in Synaptic Neuroscience, 2018 This review article deals with the mechanisms of extrasynaptic release of transmitter substances, namely the release from the soma, axon and dendrites in the absence of postsynaptic counterparts.
Elaine Del-Bel, Francisco F. De-Miguel
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Phagocytic properties of lung alveolar wall cells [PDF]
, 1974 For the purpose to define the mechanism of heavy metal intoxication by inhalation, morphologic observations were made on rat lungs after nasal instillation of iron colloid particles of positive and negative electric charges. Histochemical observation was
Tanaka, Akisuke
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Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations. [PDF]
, 2015 PurposeThe phenotypic manifestations of cerebral cavernous malformation disease caused by rare PDCD10 mutations have not been systematically examined, and a mechanistic link to Rho kinase-mediated hyperpermeability, a potential therapeutic target, has ...
Akers, Amy L +16 more
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Bilateral lichen striatus: A case report with review of literature
Indian Dermatology Online Journal, 2017 Lichen striatus is a self-limiting dermatosis presenting with sudden eruption of lichenoid papules along the lines of Blaschko. A 5-year-old girl presented with asymptomatic hypopigmented linear lesions over both upper limbs.
Aastha Gupta +2 more
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Intertwined Functions of Separase and Caspase in Cell Division and Programmed Cell Death. [PDF]
, 2020 Timely sister chromatid separation, promoted by separase, is essential for faithful chromosome segregation. Separase is a member of the CD clan of cysteine proteases, which also includes the pro-apoptotic enzymes known as caspases.
Jeong, Pan Young +3 more
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Molecular triggers of egg activation at fertilization in mammals [PDF]
, 2016 In mammals, the sperm activates the development of the egg by triggering a series of oscillations in the cytosolic-free Ca2+concentration (Ca2+i). The sperm triggers these cytosolic Ca2+ioscillations after sperm–egg membrane fusion, as well as after ...
Sanders, Jessica R., Swann, Karl
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Photoreceptor Outer Segment-like Structures in Long-Term 3D Retinas from Human Pluripotent Stem Cells. [PDF]
, 2017 The retinal degenerative diseases, which together constitute a leading cause of hereditary blindness worldwide, are largely untreatable. Development of reliable methods to culture complex retinal tissues from human pluripotent stem cells (hPSCs) could ...
Angueyra, Juan M +9 more
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