Results 41 to 50 of about 76,537 (156)

JNK signaling coordinates epithelial cell turnover through exocytosis in Drosophila ribosomal protein mutants

iScience
Summary: Robust tissue growth is orchestrated by the precise coordination of cell death and cell proliferation. In the developing wing pouches of Drosophila Minute/+ animals, both cell death and compensatory cell proliferation are increased, thereby ...
Nanami Akai, Yoshimasa Yagi, Tatsushi Igaki, Shizue Ohsawa   +3 more
doaj   +1 more source

A novel function of Noc2 in agonist-induced intracellular Ca2+ increase during zymogen-granule exocytosis in pancreatic acinar cells.

PLoS ONE, 2012
Noc2, a putative Rab effector, contributes to secretory-granule exocytosis in neuroendocrine and exocrine cells. Here, using two-photon excitation live-cell imaging, we investigated its role in Ca(2+)-dependent zymogen granule (ZG) exocytosis in ...
Sho Ogata, Takashi Miki, Susumu Seino, Seiichi Tamai, Haruo Kasai, Tomomi Nemoto   +5 more
doaj   +1 more source

Exocytosis of the silicified cell wall of diatoms involves extensive membrane disintegration

Nature Communications, 2023
Exocytosis is a fundamental cellular process. Here, the authors report an unusual exocytosis mechanism in the silicified cell wall of diatoms, in which membrane patches are discarded.
Diede de Haan, Lior Aram, Hadas Peled-Zehavi, Yoseph Addadi, Oz Ben-Joseph, Ron Rotkopf, Nadav Elad, Katya Rechav, Assaf Gal   +8 more
doaj   +1 more source

Focal exocytosis by eosinophils--compound exocytosis and cumulative fusion. [PDF]

The EMBO Journal, 1993
We have investigated the granule fusion events during exocytosis in horse eosinophils by time-resolved patch-clamp capacitance measurements. Stimulation with intracellular GTP gamma S leads to a stepwise capacitance increase by 4.0 +/- 0.9 pF. At GTP gamma S concentrations < 20 microM the step size distribution is in agreement with the granule size ...
Scepek, S., Lindau, M.
openaire   +4 more sources

A Novel Anti-Inflammatory Effect for High Density Lipoprotein.

PLoS ONE, 2015
High density lipoprotein has anti-inflammatory effects in addition to mediating reverse cholesterol transport. While many of the chronic anti-inflammatory effects of high density lipoprotein (HDL) are attributed to changes in cell adhesion molecules ...
Scott J Cameron, Craig N Morrell, Clare Bao, AnneMarie F Swaim, Annabelle Rodriguez, Charles J Lowenstein   +5 more
doaj   +1 more source

Exocytosis and Endocytosis: Yin-Yang Crosstalk for Sculpting a Dynamic Growing Pollen Tube Tip

Frontiers in Plant Science, 2020
The growing pollen tube has become one of the most fascinating model cell systems for investigations into cell polarity and polar cell growth in plants.
Lifeng Zhao, Muhammad Saad Rehmani, Hao Wang   +2 more
doaj   +1 more source

HIV-1 gp120 Promotes Lysosomal Exocytosis in Human Schwann Cells

Frontiers in Cellular Neuroscience, 2019
Human immunodeficiency virus type 1 (HIV-1) associated neuropathy is the most common neurological complication of HIV-1, with debilitating pain affecting the quality of life.
Gaurav Datta, Nicole M. Miller, Zahra Afghah, Jonathan D. Geiger, Xuesong Chen   +4 more
doaj   +1 more source

Nonlytic Exocytosis of Cryptococcus neoformans from Macrophages Occurs In Vivo and Is Influenced by Phagosomal pH

mBio, 2011
A unique aspect of the interaction of the fungus Cryptococcus neoformans with macrophages is the phenomenon of nonlytic exocytosis, also referred to as “vomocytosis” or phagosome extrusion/expulsion, which involves the escape of fungal cells from the ...
André Moraes Nicola, Emma J. Robertson, Patrícia Albuquerque, Lorena da Silveira Derengowski, Arturo Casadevall   +4 more
doaj   +1 more source

Rab10 regulates neuropeptide release by maintaining Ca2+ homeostasis and protein synthesis

eLife
Dense core vesicles (DCVs) transport and release various neuropeptides and neurotrophins that control diverse brain functions, but the DCV secretory pathway remains poorly understood.
Jian Dong, Miao Chen, Jan RT van Weering, Natalia Domínguez, Ka Wan Li, August B Smit, Ruud F Toonen, Matthijs Verhage   +7 more
doaj   +1 more source

Exocytosis of Alphaherpesvirus Virions, Light Particles, and Glycoproteins Uses Constitutive Secretory Mechanisms

mBio, 2016
Many molecular and cell biological details of the alphaherpesvirus assembly and egress pathway remain unclear. Recently we developed a live-cell fluorescence microscopy assay of pseudorabies virus (PRV) exocytosis, based on total internal reflection ...
Ian B. Hogue, Julian Scherer, Lynn W. Enquist   +2 more
doaj   +1 more source