Results 21 to 30 of about 99,750 (290)

Molecular Aspects of Secretory Granule Exocytosis by Neurons and Endocrine Cells [PDF]

, 1994
Neuronal communication and endocrine signaling are fundamental for integrating the function of tissues and cells in the body. Hormones released by endocrine cells are transported to the target cells through the circulation.
MANFRED GRATZL, Gratzl, Manfred
core   +1 more source

GLUT4 exocytosis

Journal of Cell Science, 2011
GLUT4 is an insulin-regulated glucose transporter that is responsible for insulin-regulated glucose uptake into fat and muscle cells. In the absence of insulin, GLUT4 is mainly found in intracellular vesicles referred to as GLUT4 storage vesicles (GSVs).
Jacqueline, Stöckli, Daniel J, Fazakerley, David E, James   +2 more
openaire   +3 more sources

Exocytosis of ATP from astrocytes modulates phasic and tonic inhibition in the neocortex [PDF]

, 2014
Communication between neuronal and glial cells is important for many brain functions. Astrocytes can modulate synaptic strength via Ca2+-stimulated release of various gliotransmitters, including glutamate and ATP. A physiological role of ATP release from
Lalo, Ulyana, Pankratov, Yuriy, Palygin, Oleg, Oleg Palygin (407627), Philip G Haydon, Ulyana Lalo (506296), Yuriy Pankratov, Seyed Rasooli-Nejad (506297), Rasooli-Nejad, Seyed, Yuriy Pankratov (407630), Oleg Palygin, Ulyana Lalo, Haydon, Philip G., Jemma Andrew, Jemma Andrew (506298), Philip G. Haydon (506299), Andrew, Jemma, Seyed Rasooli-Nejad, Pankratov Yuriy, Lalo Ulyana, Andrew Jemma, Palygin Oleg, Rasooli-Nejad Seyed, Haydon Philip G.   +23 more
core   +2 more sources

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

The pair ceramide 1-phosphate/ceramide kinase regulates intracellular calcium and progesterone-induced human sperm acrosomal exocytosis

Frontiers in Cell and Developmental Biology, 2023
Before fertilization, spermatozoa must undergo calcium-regulated acrosome exocytosis in response to physiological stimuli such as progesterone and zona pellucida.
Cintia C. Vaquer, Laila Suhaiman, Laila Suhaiman, Martín A. Pavarotti, Rodolfo J. Arias, Rodolfo J. Arias, Anahí B. Pacheco Guiñazú, Gerardo A. De Blas, Gerardo A. De Blas, Silvia A. Belmonte, Silvia A. Belmonte   +10 more
doaj   +1 more source

An Approach to Monitor Exocytosis in

, 2020
Exocytosis, the fusion of vesicles with the plasma membrane, can be measured with the patch-clamp technique as increases in membrane capacitance. Here we provide detailed information on how to monitor white adipocyte exocytosis using this method.
Komai, Ali,, Man Mohan Shrestha, Saliha Musovic, Ali M. Komai, Olofsson, Charlotta S,, Shrestha, Man Mohan,, Saliha, Musovic,, Charlotta S. Olofsson   +7 more
core   +1 more source

Effects of the surface charge of polyamidoamine dendrimers on cellular exocytosis and the exocytosis mechanism in multidrug-resistant breast cancer cells

Journal of Nanobiotechnology, 2021
Background Polyamidoamine (PAMAM) dendrimer applications have extended from tumor cells to multidrug-resistant tumor cells. However, their transportation in multidrug-resistant tumor cells remains unclear.
Jie Zhang, Mingjuan Li, Mingyue Wang, Hang Xu, Zhuoxiang Wang, Yue Li, Baoyue Ding, Jianqing Gao   +7 more
doaj   +1 more source

The light chain of tetanus toxin inhibits calcium-dependent vasopressin release from permeabilized nerve endings [PDF]

, 1992
The effects of tetanus toxin and its light and heavy chain subunits on vasopressin release were investigated in digitonin-permeabilized neurosecretory nerve terminals isolated from the neural lobe of the rat pituitary gland.
Weller, U., Nordmann, J. J., Dayanithi, G., Ahnert-Hilger, G., Lnk, H., Gratzl, Manfred   +5 more
core   +1 more source

Focal exocytosis by eosinophils‐‐compound exocytosis and cumulative fusion. [PDF]

The EMBO Journal, 1993
We have investigated the granule fusion events during exocytosis in horse eosinophils by time-resolved patch-clamp capacitance measurements. Stimulation with intracellular GTP gamma S leads to a stepwise capacitance increase by 4.0 +/- 0.9 pF. At GTP gamma S concentrations < 20 microM the step size distribution is in agreement with the granule size ...
Scepek, S., Lindau, M.
openaire   +4 more sources

Extrasynaptic exocytosis and its mechanisms: a source of molecules mediating volume transmission in the nervous system

Frontiers in Physiology, 2012
We review the evidence of exocytosis from extrasynaptic sites in the soma, dendrites and axonal varicosities of central and peripheral neurons of vertebrates and invertebrates, and how it may contribute to signaling in the nervous system.
Citlali eTrueta, Francisco Fernandez De-Miguel   +1 more
doaj   +1 more source