Results 21 to 30 of about 21,092 (247)

The pair ceramide 1-phosphate/ceramide kinase regulates intracellular calcium and progesterone-induced human sperm acrosomal exocytosis

open access: yesFrontiers in Cell and Developmental Biology, 2023
Before fertilization, spermatozoa must undergo calcium-regulated acrosome exocytosis in response to physiological stimuli such as progesterone and zona pellucida.
Cintia C. Vaquer   +10 more
doaj   +1 more source

Differential cargo mobilisation within Weibel-Palade bodies after transient fusion with the plasma membrane. [PDF]

open access: yes, 2014
Inflammatory chemokines can be selectively released from Weibel-Palade bodies (WPBs) during kiss-and-run exocytosis. Such selectivity may arise from molecular size filtering by the fusion pore, however differential intra-WPB cargo re-mobilisation ...
Knipe, Laura   +19 more
core   +1 more source

An Approach to Monitor Exocytosis in

open access: yes, 2020
Exocytosis, the fusion of vesicles with the plasma membrane, can be measured with the patch-clamp technique as increases in membrane capacitance. Here we provide detailed information on how to monitor white adipocyte exocytosis using this method.
Komai, Ali,   +7 more
core   +1 more source

Focal exocytosis by eosinophils‐‐compound exocytosis and cumulative fusion. [PDF]

open access: yesThe EMBO Journal, 1993
We have investigated the granule fusion events during exocytosis in horse eosinophils by time-resolved patch-clamp capacitance measurements. Stimulation with intracellular GTP gamma S leads to a stepwise capacitance increase by 4.0 +/- 0.9 pF. At GTP gamma S concentrations < 20 microM the step size distribution is in agreement with the granule size ...
Scepek, S., Lindau, M.
openaire   +4 more sources

Extrasynaptic exocytosis and its mechanisms: a source of molecules mediating volume transmission in the nervous system

open access: yesFrontiers in Physiology, 2012
We review the evidence of exocytosis from extrasynaptic sites in the soma, dendrites and axonal varicosities of central and peripheral neurons of vertebrates and invertebrates, and how it may contribute to signaling in the nervous system.
Citlali eTrueta   +1 more
doaj   +1 more source

SNAP23 Regulates Endothelial Exocytosis of von Willebrand Factor. [PDF]

open access: yesPLoS ONE, 2015
Endothelial exocytosis regulates vascular thrombosis and inflammation. The trafficking and release of endothelial vesicles is mediated by SNARE (Soluble NSF Attachment protein REceptors) molecules, but the exact identity of endothelial SNAREs has been ...
Qiuyu Martin Zhu   +2 more
doaj   +1 more source

Exocytosis of serotonin from the neuronal soma is sustained by a serotonin and calcium-dependent feedback loop

open access: yesFrontiers in Cellular Neuroscience, 2014
The soma of many neurons releases large amounts of transmitter molecules through an exocytosis process that continues for hundreds of seconds after the end of the triggering stimulus.
Carolina eLeon-Pinzon   +4 more
doaj   +1 more source

An inhibitory effect of extracellular Ca2+ on Ca2+-dependent exocytosis. [PDF]

open access: yesPLoS ONE, 2011
AIM: Neurotransmitter release is elicited by an elevation of intracellular Ca(2+) concentration ([Ca(2+)](i)). The action potential triggers Ca(2+) influx through Ca(2+) channels which causes local changes of [Ca(2+)](i) for vesicle release. However, any
Wei Xiong   +11 more
doaj   +1 more source

The light chain of tetanus toxin inhibits calcium-dependent vasopressin release from permeabilized nerve endings [PDF]

open access: yes, 1992
The effects of tetanus toxin and its light and heavy chain subunits on vasopressin release were investigated in digitonin-permeabilized neurosecretory nerve terminals isolated from the neural lobe of the rat pituitary gland.
Weller, U.   +5 more
core   +1 more source

Munc13 mediates klotho-inhibitable diacylglycerol-stimulated exocytotic insertion of pre-docked TRPC6 vesicles.

open access: yesPLoS ONE, 2020
α-Klotho is a type 1 transmembrane protein that exhibits aging suppression function. The large amino-terminal extracellular domain of α-klotho is shed as soluble klotho (sKlotho) and functions as a circulating cardioprotective hormone.
Jian Xie   +4 more
doaj   +1 more source

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