Results 21 to 30 of about 151,391 (333)

An inhibitory effect of extracellular Ca2+ on Ca2+-dependent exocytosis. [PDF]

PLoS ONE, 2011
AIM: Neurotransmitter release is elicited by an elevation of intracellular Ca(2+) concentration ([Ca(2+)](i)). The action potential triggers Ca(2+) influx through Ca(2+) channels which causes local changes of [Ca(2+)](i) for vesicle release. However, any
Wei Xiong, Tao Liu, Yeshi Wang, Xiaowei Chen, Lei Sun, Ning Guo, Hui Zheng, Lianghong Zheng, Martial Ruat, Weiping Han, Claire Xi Zhang, Zhuan Zhou   +11 more
doaj   +1 more source

Microelectrode arrays of diamond-insulated graphitic channels for real time detection of exocytotic events from cultured chromaffin cells and slices of adrenal glands [PDF]

, 2016
A microstructured graphitic 4x4 multielectrode array was embedded in a single crystal diamond substrate (4x4 {uG-SCD MEA) for real-time monitoring of exocytotic events from cultured chromaffin cells and adrenal slices.
Battiato, A., Bernardi, E., Carabelli, V., Carbone, E., Marcantoni, A., Olivero, P., Pasquarelli, A., Picollo, F.   +7 more
core   +3 more sources

Extrasynaptic exocytosis and its mechanisms: a source of molecules mediating volume transmission in the nervous system

Frontiers in Physiology, 2012
We review the evidence of exocytosis from extrasynaptic sites in the soma, dendrites and axonal varicosities of central and peripheral neurons of vertebrates and invertebrates, and how it may contribute to signaling in the nervous system.
Citlali eTrueta, Francisco Fernandez De-Miguel   +1 more
doaj   +1 more source

The rab3A-22A chimera prevents sperm exocytosis by stabilizing open fusion pores [PDF]

, 2016
At the final stage of exocytotis, a fusion pore opens between the plasma and a secretory vesicle membranes; typically, when the pore dilates the vesicle releases its cargo.
Bustos, Matias Alberto, De la Iglesia, Paola X., Lucchesi, Ornella, Pocognoni, Cristián Adrián, Quevedo, María Florencia, Tomes, Claudia Nora   +5 more
core   +1 more source

CaMKIIalpha interacts with multi-PDZ domain protein MUPP1 in spermatozoa and prevents spontaneous acrosomal exocytosis [PDF]

, 2009
The success of acrosomal exocytosis, a complex process with a variety of inter-related steps, relies on the coordinated interaction of participating signaling molecules.
Ackermann, Frauke, Boekhoff, Ingrid, Borth, Heike, Buech, Thomas, Gudermann, Thomas, Zitranski, Nele   +5 more
core   +1 more source

Exocytosis of serotonin from the neuronal soma is sustained by a serotonin and calcium-dependent feedback loop

Frontiers in Cellular Neuroscience, 2014
The soma of many neurons releases large amounts of transmitter molecules through an exocytosis process that continues for hundreds of seconds after the end of the triggering stimulus.
Carolina eLeon-Pinzon, Montserrat G. Cercós, Paula eNoguez, Citlali eTrueta, Francisco eF. De-Miguel   +4 more
doaj   +1 more source

Munc13 mediates klotho-inhibitable diacylglycerol-stimulated exocytotic insertion of pre-docked TRPC6 vesicles.

PLoS ONE, 2020
α-Klotho is a type 1 transmembrane protein that exhibits aging suppression function. The large amino-terminal extracellular domain of α-klotho is shed as soluble klotho (sKlotho) and functions as a circulating cardioprotective hormone.
Jian Xie, Sung-Wan An, Xin Jin, Yuan Gui, Chou-Long Huang   +4 more
doaj   +1 more source

Introduction of Macromolecules into Bovine Adrenal Medullary Chromaffin Cells and Rat Pheochromocytoma Cells (PC12) by Permeabilization with Streptolysin O: Inhibitory Effect of Tetanus Toxin on Catecholamine Secretion [PDF]

, 1989
Conditions are described for controlled plasma membrane permeabilization of rat pheochromocytoma cells (PC12) and cultured bovine adrenal chromaffin cells by Streptolysin O (SLO).
Ahnert-Hilger G., Ahnert-Hilger G., Ahnert-Hilger G., Bader M. F., Bhakdi S., Bhakdi S., Bhakdi S., Bittner M. A., Brooks J. C., Cazalis M., Duncan J. L., Flodgaard H., Gudrun Ahnert-Hilger, Habermann E., Hugo F., Jahn R., Knight D. E, Manfred Gratzl, Marie-France Bader, Peppers S. C., Rehm H., Sarafian T., Sillen L. G., Simon W., Smyth C. I., Sontag J. M., Sternberger A., Sucharit Bhakdi, Walton K. M., Wilson S. P.   +29 more
core   +1 more source

Temperature-dependence of Weibel-Palade body exocytosis and cell surface dispersal of von Willebrand factor and its propolypeptide.

PLoS ONE, 2011
BackgroundWeibel-Palade bodies (WPB) are endothelial cell (EC) specific secretory organelles containing Von Willebrand factor (VWF). The temperature-dependence of Ca(2+)-driven WPB exocytosis is not known, although indirect evidence suggests that WPB ...
Lindsay Hewlett, Gregor Zupančič, Gregory Mashanov, Laura Knipe, David Ogden, Matthew J Hannah, Tom Carter   +6 more
doaj   +1 more source

A Novel Role of the TRPM4 Ion Channel in Exocytosis

Cells, 2022
Under physiological conditions, the widely expressed calcium-activated TRPM4 channel conducts sodium into cells. This sodium influx depolarizes the plasma membrane and reduces the driving force for calcium entry.
Paulina Stokłosa, Sven Kappel, Christine Peinelt   +2 more
doaj   +1 more source