Results 11 to 20 of about 76,875 (253)
Exocytosis through the lens [PDF]
Frontiers in Endocrinology, 2013 Exocytosis, the process in which material is transported from the cell interior to the extracellular space, proceeds through a complex mechanism. Defects in this process are linked to a number of serious illnesses including diabetes, cancer and a range ...
Alicja eGraczyk, Colin eRickman
doaj +3 more sources
Exocytosis in Astrocytes [PDF]
Biomolecules, 2021 Until recently, astrocytes were thought to be a part of a simple “brain glue” providing only a supporting role for neurons. However, the discoveries of the last two decades have proven astrocytes to be dynamic partners participating in brain metabolism and actively influencing communication between neurons.
Aleksandra Mielnicka, Piotr Michaluk
openaire +3 more sources
Exocytosis and Endocytosis [PDF]
The Plant Cell, 1999 Exocytosis is a general term used to denote vesicle fusion at the plasma membrane, and it is the final step in the secretory pathway that typically begins in the endoplasmic reticulum (ER), passes through the Golgi apparatus, and ends at the outside of the cell.
, Battey +3 more
openaire +2 more sources
Cold Spring Harbor Perspectives in Biology, 2017 Polarized exocytosis is generally considered as the multistep vesicular trafficking process in which membrane-bounded carriers are transported from the Golgi or endosomal compartments to specific sites of the plasma membrane. Polarized exocytosis in cells is achieved through the coordinated actions of membrane trafficking machinery and cytoskeleton ...
Jingwen, Zeng +3 more
openaire +2 more sources
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023 Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei +4 more
wiley +1 more source
Journal of Cell Science, 2011 GLUT4 is an insulin-regulated glucose transporter that is responsible for insulin-regulated glucose uptake into fat and muscle cells. In the absence of insulin, GLUT4 is mainly found in intracellular vesicles referred to as GLUT4 storage vesicles (GSVs).
Jacqueline, Stöckli +2 more
openaire +3 more sources
Focal exocytosis by eosinophils‐‐compound exocytosis and cumulative fusion. [PDF]
The EMBO Journal, 1993 We have investigated the granule fusion events during exocytosis in horse eosinophils by time-resolved patch-clamp capacitance measurements. Stimulation with intracellular GTP gamma S leads to a stepwise capacitance increase by 4.0 +/- 0.9 pF. At GTP gamma S concentrations < 20 microM the step size distribution is in agreement with the granule size ...
Scepek, S., Lindau, M.
openaire +4 more sources
An inhibitory effect of extracellular Ca2+ on Ca2+-dependent exocytosis. [PDF]
PLoS ONE, 2011 AIM: Neurotransmitter release is elicited by an elevation of intracellular Ca(2+) concentration ([Ca(2+)](i)). The action potential triggers Ca(2+) influx through Ca(2+) channels which causes local changes of [Ca(2+)](i) for vesicle release. However, any
Wei Xiong +11 more
doaj +1 more source
Frontiers in Physiology, 2012 We review the evidence of exocytosis from extrasynaptic sites in the soma, dendrites and axonal varicosities of central and peripheral neurons of vertebrates and invertebrates, and how it may contribute to signaling in the nervous system.
Citlali eTrueta +1 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2014 The soma of many neurons releases large amounts of transmitter molecules through an exocytosis process that continues for hundreds of seconds after the end of the triggering stimulus.
Carolina eLeon-Pinzon +4 more
doaj +1 more source