Results 11 to 20 of about 76,537 (156)
Spatiotemporal dynamics of signal dependent exocytosis and parasitophorous vacuolar membrane rupture during Plasmodium falciparum egress. [PDF]
PLoS PathogensMalaria, caused by intracellular Plasmodium falciparum parasites, remains a major global health concern. These parasites reside and replicate within a vacuole in host red blood cells. Egress of daughter parasites out of the vacuolar and host membranes is
Watcharatip Dedkhad +4 more
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Exocytosis through the lens [PDF]
Frontiers in Endocrinology, 2013 Exocytosis, the process in which material is transported from the cell interior to the extracellular space, proceeds through a complex mechanism. Defects in this process are linked to a number of serious illnesses including diabetes, cancer and a range ...
Alicja eGraczyk, Colin eRickman
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Exocytosis in Astrocytes [PDF]
Biomolecules, 2021 Until recently, astrocytes were thought to be a part of a simple “brain glue” providing only a supporting role for neurons. However, the discoveries of the last two decades have proven astrocytes to be dynamic partners participating in brain metabolism and actively influencing communication between neurons.
Aleksandra Mielnicka, Piotr Michaluk
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iScience, 2023 Summary: Glucocorticoid use is associated with steroid-induced diabetes mellitus and impaired pancreatic β-cell insulin secretion. Here, the glucocorticoid-mediated transcriptomic changes in human pancreatic islets and the human insulin-secreting EndoC ...
Alexandros Karagiannopoulos +5 more
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Exocytosis and Endocytosis [PDF]
The Plant Cell, 1999 Exocytosis is a general term used to denote vesicle fusion at the plasma membrane, and it is the final step in the secretory pathway that typically begins in the endoplasmic reticulum (ER), passes through the Golgi apparatus, and ends at the outside of the cell.
, Battey +3 more
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MARCKS protein is phosphorylated and regulates calcium mobilization during human acrosomal exocytosis. [PDF]
PLoS ONE, 2013 Acrosomal exocytosis is a calcium-regulated exocytosis that can be triggered by PKC activators. The involvement of PKC in acrosomal exocytosis has not been fully elucidated, and it is unknown if MARCKS, the major substrate for PKC, participates in this ...
Marcelo J Rodriguez Peña +4 more
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Cold Spring Harbor Perspectives in Biology, 2017 Polarized exocytosis is generally considered as the multistep vesicular trafficking process in which membrane-bounded carriers are transported from the Golgi or endosomal compartments to specific sites of the plasma membrane. Polarized exocytosis in cells is achieved through the coordinated actions of membrane trafficking machinery and cytoskeleton ...
Jingwen, Zeng +3 more
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Glucocorticoid induces human beta cell dysfunction by involving riborepressor GAS5 LincRNA
Molecular Metabolism, 2020 Objective: A widely recognized metabolic side effect of glucocorticoid (GC) therapy is steroid-induced diabetes mellitus (DM). However, studies on the molecular basis of GC-induced pancreatic beta cell dysfunction in human beta cells are lacking.
Jonathan L.S. Esguerra +8 more
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Frontiers in Molecular Neuroscience, 2021 Streams of action potentials or long depolarizations evoke a massive exocytosis of transmitters and peptides from the surface of dendrites, axons and cell bodies of different neuron types.
Francisco F. De-Miguel +13 more
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eLife, 2016 The hormones insulin and glucagon both play important roles in the development of diabetes.
Lena Eliasson, Anna Wendt
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