Results 11 to 20 of about 99,750 (290)

Exocytosis through the lens [PDF]

open access: yesFrontiers in Endocrinology, 2013
Exocytosis, the process in which material is transported from the cell interior to the extracellular space, proceeds through a complex mechanism. Defects in this process are linked to a number of serious illnesses including diabetes, cancer and a range ...
Alicja eGraczyk, Colin eRickman
doaj   +5 more sources

Temperature-dependence of Weibel-Palade body exocytosis and cell surface dispersal of von Willebrand factor and its propolypeptide. [PDF]

open access: yesPLoS ONE, 2011
BackgroundWeibel-Palade bodies (WPB) are endothelial cell (EC) specific secretory organelles containing Von Willebrand factor (VWF). The temperature-dependence of Ca(2+)-driven WPB exocytosis is not known, although indirect evidence suggests that WPB ...
Lindsay Hewlett   +6 more
doaj   +2 more sources

A Novel Role of the TRPM4 Ion Channel in Exocytosis [PDF]

open access: yesCells, 2022
Under physiological conditions, the widely expressed calcium-activated TRPM4 channel conducts sodium into cells. This sodium influx depolarizes the plasma membrane and reduces the driving force for calcium entry.
Paulina Stokłosa   +2 more
doaj   +3 more sources

Anaphylactic Degranulation of Mast Cells: Focus on Compound Exocytosis

open access: yesJournal of Immunology Research, 2019
Anaphylaxis is a notorious type 2 immune response which may result in a systemic response and lead to death. A precondition for the unfolding of the anaphylactic shock is the secretion of inflammatory mediators from mast cells in response to an allergen,
Ofir Klein, Ronit Sagi-Eisenberg
doaj   +2 more sources

SNAP23 Regulates Endothelial Exocytosis of von Willebrand Factor. [PDF]

open access: yesPLoS ONE, 2015
Endothelial exocytosis regulates vascular thrombosis and inflammation. The trafficking and release of endothelial vesicles is mediated by SNARE (Soluble NSF Attachment protein REceptors) molecules, but the exact identity of endothelial SNAREs has been ...
Qiuyu Martin Zhu   +2 more
doaj   +2 more sources

SIP30 involvement in vesicle exocytosis from PC12 cells

open access: yesBiochemistry and Biophysics Reports
SNAP25 (synaptosome-associated protein of 25 kDa) is a core SNARE (soluble N-ethylmaleimide-sensitive factor attachment receptor) protein; and the interaction between SNAP25 and other SNARE proteins is essential for synaptic vesicle exocytosis ...
Ning Guo, Lei Yu
doaj   +2 more sources

Exocytosis in Astrocytes [PDF]

open access: yesBiomolecules, 2021
Until recently, astrocytes were thought to be a part of a simple “brain glue” providing only a supporting role for neurons. However, the discoveries of the last two decades have proven astrocytes to be dynamic partners participating in brain metabolism and actively influencing communication between neurons.
Aleksandra Mielnicka, Piotr Michaluk
openaire   +3 more sources

Exocytosis and Endocytosis [PDF]

open access: yesThe Plant Cell, 1999
Exocytosis is a general term used to denote vesicle fusion at the plasma membrane, and it is the final step in the secretory pathway that typically begins in the endoplasmic reticulum (ER), passes through the Golgi apparatus, and ends at the outside of the cell.
, Battey   +3 more
openaire   +2 more sources

Polarized Exocytosis [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2017
Polarized exocytosis is generally considered as the multistep vesicular trafficking process in which membrane-bounded carriers are transported from the Golgi or endosomal compartments to specific sites of the plasma membrane. Polarized exocytosis in cells is achieved through the coordinated actions of membrane trafficking machinery and cytoskeleton ...
Jingwen, Zeng   +3 more
openaire   +2 more sources

CaMKIIalpha interacts with multi-PDZ domain protein MUPP1 in spermatozoa and prevents spontaneous acrosomal exocytosis [PDF]

open access: yes, 2009
The success of acrosomal exocytosis, a complex process with a variety of inter-related steps, relies on the coordinated interaction of participating signaling molecules.
Borth, Heike   +5 more
core   +1 more source

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