Results 31 to 40 of about 151,391 (333)

Exocytosis and Endocytosis [PDF]

The Plant Cell, 1999
Exocytosis is a general term used to denote vesicle fusion at the plasma membrane, and it is the final step in the secretory pathway that typically begins in the endoplasmic reticulum (ER), passes through the Golgi apparatus, and ends at the outside of the cell.
, Battey, , James, , Greenland, , Brownlee   +3 more
openaire   +2 more sources

Anaphylactic Degranulation of Mast Cells: Focus on Compound Exocytosis

Journal of Immunology Research, 2019
Anaphylaxis is a notorious type 2 immune response which may result in a systemic response and lead to death. A precondition for the unfolding of the anaphylactic shock is the secretion of inflammatory mediators from mast cells in response to an allergen,
Ofir Klein, Ronit Sagi-Eisenberg
doaj   +1 more source

Cortical granule exocytosis is mediated by alpha-SNAP and N-Ethilmaleimide sensitive factor in mouse eggs [PDF]

, 2015
Cortical granule exocytosis (CGE), also known as cortical reaction, is a calciumregulated secretion that represents a membrane fusion process during meiotic cell division of eggs.
Bello, Oscar Daniel, de Paola, Maria Matilde, Michaut, Marcela Alejandra   +2 more
core   +10 more sources

The dynamics of somatic exocytosis in monoaminergic neurons

Frontiers in Physiology, 2012
Some monoaminergic neurons can release neurotransmitters by exocytosis from their cell bodies. The amount of monoamine released by somatic exocytosis can be comparable to that released by synaptic exocytosis, though neither the underlying mechanisms nor ...
Bidyut eSarkar, Anand Kant Das, Senthil eArumugam, Sanjeev Kumar Kaushalya, Arkarup eBandyopadhyay, Jayaprakash eBalaji, Sudipta eMaiti   +6 more
doaj   +1 more source

Further Characterization of Dopamine Release by Permeabilized PC 12 Cells [PDF]

, 1987
Rat pheochromocytoma cells (PC 12) permeabilized with staphylococcal α-toxin release [3H]dopamine after addition of micromolar Ca2+. This does not require additional Mg2+-ATP (in contrast to bovine adrenal medullary chromaffin cells).
Ahnert-Hilger G., Bader M. F., Bader M. F., Baker P. F., Bhakdi S., Bhakdi S., Brooks J. C., Dunn L. A., Ekerdt R., Flodgaard H., Gratzl M., Gudrun Ahnert-Hilger, Lowry O. H., Manfred Gratzl, Rubin R. P., Sillen L. G., Simon W., Wadstrom T., Wilson S. P.   +18 more
core   +1 more source

Network-based insights into miRNA regulation of β-cell insulin secretion in type 2 diabetes

iScience
Summary: Increasing evidence suggests that microRNAs (miRNAs) contribute to pancreatic β-cell compensation during type 2 diabetes (T2D) pathogenesis. To examine miRNA-mRNA interactions in human islets and their roles in β-cell insulin secretion and T2D ...
Elaine Cowan, Alexandros Karagiannopoulos, Alessio Pollastri, Akira Asai, Mototsugu Nagao, Marlena Maziarz, Jonathan L.S. Esguerra, Lena Eliasson   +7 more
doaj   +1 more source

Epac, Rap and Rab3 act in concert to mobilize calcium from sperm's acrosome during exocytosis [PDF]

, 2014
BACKGROUND: Exocytosis of sperm's single secretory granule or acrosome (acrosome reaction, AR) is a highly regulated event essential for fertilization. The AR begins with an influx of calcium from the extracellular milieu and continues with the synthesis
Bustos, Matias Alberto, Lucchesi, Ornella, Ruete, María Celeste, Tomes, Claudia Nora   +3 more
core   +1 more source

Voltage-Dependent Calcium Channels at the Plasma Membrane, but Not Vesicular Channels, Couple Exocytosis to Endocytosis

Cell Reports, 2012
Although calcium influx triggers endocytosis at many synapses and non-neuronal secretory cells, the identity of the calcium channel is unclear. The plasma membrane voltage-dependent calcium channel (VDCC) is a candidate, and it was recently proposed that
Lei Xue, Zhen Zhang, Benjamin D. McNeil, Fujun Luo, Xin-Sheng Wu, Jiansong Sheng, Wonchul Shin, Ling-Gang Wu   +7 more
doaj   +1 more source

Myosin light chain kinase is not a regulator of synaptic vesicle trafficking during repetitive exocytosis in cultured hippocampal neurons [PDF]

, 2006
The mechanism by which synaptic vesicles (SVs) are recruited to the release site is poorly understood. One candidate mechanism for trafficking of SVs is the myosin-actin motor system.
Goda, Y, Tokuoka, H
core   +1 more source

Calcium current inactivation rather than pool depletion explains reduced exocytotic rate with prolonged stimulation in insulin-secreting INS-1 832/13 cells.

PLoS ONE, 2014
Impairment in beta-cell exocytosis is associated with reduced insulin secretion and diabetes. Here we aimed to investigate the dynamics of Ca2+-dependent insulin exocytosis with respect to pool depletion and Ca2+-current inactivation.
Morten Gram Pedersen, Vishal Ashok Salunkhe, Emma Svedin, Anna Edlund, Lena Eliasson   +4 more
doaj   +1 more source