Results 111 to 120 of about 167,613 (264)
Multiscale Modelling: A Mobile Membrane Approach [PDF]
arXiv, 2011 Nowadays, multiscale modelling is recognized as the most suitable way to study biological processes. Indeed, almost every phenomenon in nature exhibits a multiscale behaviour, i.e., it is the outcome of interactions that occur at different spatial and temporal scales. Although several ways to provide "multilayer" models have been proposed, only Complex
arxiv
Synaptobrevin cleavage by the tetanus toxin light chain is linked to the inhibition of exocytosis in chromaffin cells [PDF]
, 1994 Exocytosis of secretory granules by adrenal chromaffin cells is blocked by the tetanus toxin light chain in a zinc specific manner. Here we show that cellular synaptobrevin is almost completely degraded by the tetanus toxin light chain within 15 min.
Ahnert-Hilger +46 more
core +1 more source
mBio, 2016 Many molecular and cell biological details of the alphaherpesvirus assembly and egress pathway remain unclear. Recently we developed a live-cell fluorescence microscopy assay of pseudorabies virus (PRV) exocytosis, based on total internal reflection ...
Ian B. Hogue +2 more
doaj +1 more source
Dynamin Is Functionally Coupled to Insulin Granule Exocytosis [PDF]
, 2007 The insulin granule integral membrane protein marker phogrin-green fluorescent protein was co-localized with insulin in Min6B1 beta-cell secretory granules but did not undergo plasma membrane translocation following glucose stimulation.
Gaisano, HY +7 more
core +2 more sources
Thermodynamic Efficiency of Somatic Exocytosis of Serotonin
Frontiers in Physiology, 2019 Through somatic exocytosis neurons liberate immense amounts of transmitter molecules that modulate the functioning of the nervous system. A stream of action potentials triggers an ATP-dependent transport of transmitter-containing vesicles to the plasma ...
Paula Noguez +2 more
doaj +1 more source
Fusion of secretory vesicles isolated from rat liver [PDF]
, 1978 Secretory vesicles isolated from rat liver were found to fuse after exposure to Ca2+. Vescle fusion is characterized by the occurrence of twinned vesicles with a continuous cleavage plane between two vesicles in freeze-fracture electron microscopy.
A. Amsterdam +75 more
core +1 more source
CFTR is involved in the regulation of glucagon secretion in human and rodent alpha cells
Scientific Reports, 2017 Glucagon is the main counterregulatory hormone in the body. Still, the mechanism involved in the regulation of glucagon secretion from pancreatic alpha cells remains elusive. Dysregulated glucagon secretion is common in patients with Cystic Fibrosis (CF)
Anna Edlund +5 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2018 The intact synaptic structure is critical for information processing in neural circuits. During synaptic transmission, rapid vesicle exocytosis increases the size of never terminals and endocytosis counteracts the increase. Accumulating evidence suggests
Xuelin Lou
doaj +1 more source
Both cellular ATP level and ATP hydrolysis free energy determine energetically the calcium oscillation in pancreatic $β$-cell [PDF]
arXiv, 2018 In pancreatic $\beta$-cells, calcium oscillation signal is the core part of glucose-stimulated insulin secretion. Intracellular calcium concentration oscillates in response to the intake of glucose, which triggers the exocytosis of insulin secretory granules. ATP plays a crucial part in this process.
arxiv
PLoS Pathogens, 2014 Egress of newly assembled herpesvirus particles from infected cells is a highly dynamic process involving the host secretory pathway working in concert with viral components.
Ian B. Hogue +4 more
semanticscholar +1 more source