Results 81 to 90 of about 167,613 (264)
Visualization of the exocyst complex dynamics at the plasma membrane of Arabidopsis thaliana [PDF]
, 2013 The exocyst complex, an effector of Rho and Rab GTPases, is believed to function as an exocytotic vesicle tether at the plasma membrane before soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex formation.
De Rycke, Riet +7 more
core +2 more sources
G-Protein Coupled Receptor-Evoked Glutamate Exocytosis from Astrocytes: Role of Prostaglandins
Neural Plasticity, 2014 Astrocytes are highly secretory cells, participating in rapid brain communication by releasing glutamate. Recent evidences have suggested that this process is largely mediated by Ca2+-dependent regulated exocytosis of VGLUT-positive vesicles.
Corrado Cali +4 more
doaj +1 more source
Membrane Trafficking in the Yeast Saccharomyces cerevisiae Model [PDF]
International Journal of Molecular Sciences, MDPI, 2015, 16 (1),
pp.1509 - 1525, 2018 The yeast Saccharomyces cerevisiae is one of the best characterized eukaryotic models. The secretory pathway was the first trafficking pathway clearly understood mainly thanks to the work done in the laboratory of Randy Schekman in the 1980s. They have isolated yeast sec mutants unable to secrete an extracellular enzyme and these SEC genes were ...
arxiv +1 more source
Biology Open, 2012 Summary The abundant proteoglycan, aggrecan, is resorbed from growth plate cartilage during endochondral bone ossification, yet mice with genetically-ablated aggrecan-degrading activity have no defects in bone formation.
Edward R. Bastow +5 more
doaj +1 more source
Experimental measurement of endocytosis in fungal hyphae. [PDF]
, 2018 The present study examines the notion that polarized exocytosis in the tips of growing hyphae creates an excess of plasma membrane and thus the need for its removal by endocytosis.
Bartnicki-Garcia, Salomon +3 more
core
Frontiers in Endocrinology, 2013 Exocytosis, the process in which material is transported from the cell interior to the extracellular space, proceeds through a complex mechanism. Defects in this process are linked to a number of serious illnesses including diabetes, cancer and a range ...
Alicja eGraczyk, Colin eRickman
doaj +1 more source
Exocytosis and Endocytosis: Yin-Yang Crosstalk for Sculpting a Dynamic Growing Pollen Tube Tip
Frontiers in Plant Science, 2020 The growing pollen tube has become one of the most fascinating model cell systems for investigations into cell polarity and polar cell growth in plants.
Lifeng Zhao +2 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2021 Huntington disease (HD) is a monogenic disease that results in a combination of motor, psychiatric and cognitive symptoms. HD is caused by a CAG trinucleotide repeat expansion in the huntingtin (HTT) gene, which results in the production of a pathogenic ...
Jessica C. Barron +2 more
doaj +1 more source
Epac, Rap and Rab3 act in concert to mobilize calcium from sperm's acrosome during exocytosis [PDF]
, 2014 BACKGROUND: Exocytosis of sperm's single secretory granule or acrosome (acrosome reaction, AR) is a highly regulated event essential for fertilization. The AR begins with an influx of calcium from the extracellular milieu and continues with the synthesis
Bustos, Matias Alberto +3 more
core +1 more source
PLoS ONE, 2012 Noc2, a putative Rab effector, contributes to secretory-granule exocytosis in neuroendocrine and exocrine cells. Here, using two-photon excitation live-cell imaging, we investigated its role in Ca(2+)-dependent zymogen granule (ZG) exocytosis in ...
Sho Ogata +5 more
doaj +1 more source