Results 201 to 210 of about 51,494 (318)

RNA Therapeutics for Duchenne Muscular Dystrophy: Exon Skipping, RNA Editing, and Translational Insights from Genome-Edited Microminipig Models. [PDF]

Int J Mol Sci
Chassin A, Ono H, Ashida Y, Imamura M, Aoki Y.   +4 more
europepmc   +1 more source

Unraveling the nexus: Tumor mutational burden, PD‐L1 expression, and oncogenic alterations in non–small cell lung cancer cytology specimens

Cancer Cytopathology, Volume 134, Issue 4, April 2026.
Abstract Background PD‐L1 expression and tumor mutational burden (TMB) are biomarkers for immune checkpoint inhibitor (ICI) therapy in non–small cell lung cancer (NSCLC); however, patients harboring oncogenic alterations have limited benefit from ICIs.
Min Dai, Francis Anthony San Lucas, Hector Alvarez, Leomar Ballester, Hui Chen, Keyur P. Patel, Asif Rashid, Shun Rao, Mark J. Routbort, Gloria Sura, Keith Sweeney, Gokce Toruner, Peng Wei, Richard Yang, Hyvan Dang, Rajyalakshmi Luthra, Sinchita Roy‐Chowdhuri   +16 more
wiley   +1 more source

Improving angiogenesis ameliorates the efficacy of ASO-based exon skipping for the treatment of Duchenne muscular dystrophy. [PDF]

Mol Ther Nucleic Acids
Blitek M, Gastaldi C, Doisy M, Le Coz O, David M, Phongsavanh X, Ben Aicha S, Garcia L, Rotini A, Pagès G, Goyenvalle A.   +10 more
europepmc   +1 more source

Pleomorphic Carcinoma With EGFR and Concomitant Mutations Transformed From Lung Adenocarcinoma: A Case Report

Cancer Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background Transformation to small cell carcinoma, squamous cell carcinoma, and rarely, pleomorphic carcinoma (PC) has been reported to be found in EGFR‐mutated lung cancer with acquired resistance to EGFR tyrosine kinase inhibitors (TKIs). However, evidence for underlying factors including genomic profiles associated with PC transformation ...
Yuki Akazawa, Takashi Sato, Yuri Yagami, Yurika Kesen, Tomohiro Furo, Atsuko Watanabe, Jumpei Endo, Maito Nakano, Hiroto Kurata, Hiromi Matsuo, Yoshiro Nakahara, Jiichiro Sasaki, Katsuhiko Naoki   +12 more
wiley   +1 more source

A novel non-sense variant in <i>GSDME</i> causing exon skipping associated with DFNA5 in a large Chinese family. [PDF]

Front Neurol
Yang B, Zhu M, Long X, Wan S, Lu Y, Yuan H, Hua Q.   +6 more
europepmc   +1 more source

MET Exon 14 Skipping Mutation [PDF]

, 2020
openaire   +1 more source

Lower Dose‐Normalized Tacrolimus Exposure in CYP3A5*6 vs. *3 Loss‐of‐Function Allele Carriers: A Longitudinal Retrospective Real‐World Study in Kidney Transplant Recipients

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 942-952, April 2026.
Pharmacogenomic research has historically focused on individuals of European ancestry, leading to the underrepresentation of genetic variants common in non‐European populations. This bias is exemplified by CYP3A5*6, a functionally consequential variant common in individuals of African ancestry (MAF: 11–19%) but virtually absent in Europeans (MAF: 0.15%)
Amar D. Levens, Dirk Jan A. R. Moes, Yanick Boer, Aiko P. J. de Vries, Dorottya K. de Vries, Danny van der Helm, Soufian Meziyerh, Dave L. Roelen, Stefan Böhringer, Teun Van Gelder, Jesse J. Swen   +10 more
wiley   +1 more source

Exon skipping peptide-conjugated morpholinos downregulate dynamin 2 to rescue centronuclear myopathy. [PDF]

Brain
Moschovaki-Filippidou F, de Carvalho Neves J, Diedhiou N, Jad Y, Böhm J, Wood MJA, Varela MA, Laporte J.   +7 more
europepmc   +1 more source

Figure S4 from Exon Skipping of <i>Ste20-</i><i>Like</i><i> Kinase</i> Enhances Glycolysis and Tumor Progression by Activating Enolase 1–Mediated Phosphoenolpyruvate Production

Zeyu Chen, Jingyu Liao, Chang Zhu, Ruizhi Chang, Huifang Liang, Zeyang Ding, Zhao Huang, Xiaoping Chen, Jia Liang, Bixiang Zhang   +9 more
openalex   +1 more source

β‐Spectrin Campinas: a novel shortened β‐chain variant associated with skipping of exon 30 and hereditary elliptocytosis [PDF]

, 1997
Daniela S. Daniela Sanchez Bassères, Patrícia Pranke, Tereza S. I. Sales, Fernando Ferreira Costa, Sara T.O. Saad   +4 more
openalex   +1 more source