Results 211 to 220 of about 18,119 (268)
Some of the next articles are maybe not open access.
Current Protocols in Molecular Biology, 2011
AbstractReaction conditions for numerous exonucleases are detailed in this unit along with discussions of potential applications and preferred substrates. Single‐stranded and double‐stranded 5′ →︀ 3′ and 3′ →︀ 5′ exonucleases are included. Curr. Protoc. Mol. Biol. 96:3.11.1‐3.11.7. © 2011 by John Wiley & Sons, Inc.
Larry A. McReynolds, Nicole M. Nichols
exaly +2 more sources
AbstractReaction conditions for numerous exonucleases are detailed in this unit along with discussions of potential applications and preferred substrates. Single‐stranded and double‐stranded 5′ →︀ 3′ and 3′ →︀ 5′ exonucleases are included. Curr. Protoc. Mol. Biol. 96:3.11.1‐3.11.7. © 2011 by John Wiley & Sons, Inc.
Larry A. McReynolds, Nicole M. Nichols
exaly +2 more sources
Nature Reviews Molecular Cell Biology, 2002
Over the past few years, several new 3' 5' exonucleases have been identified. In vitro studies of these enzymes have uncovered much about their potential functions in vivo, and certain organisms with a defect in 3' 5' exonucleases have an increased susceptibility to cancer, especially under conditions of stress.
Shevelev, I V, Hübscher, U
exaly +4 more sources
Over the past few years, several new 3' 5' exonucleases have been identified. In vitro studies of these enzymes have uncovered much about their potential functions in vivo, and certain organisms with a defect in 3' 5' exonucleases have an increased susceptibility to cancer, especially under conditions of stress.
Shevelev, I V, Hübscher, U
exaly +4 more sources
Current Protocols in Molecular Biology, 1987
AbstractReaction conditions for numerous exonucleases are detailed in this unit along with discussions of potential applications. Single‐stranded and double‐stranded 5′ => 3′ and 3′ => 5′ exonucleases are included.
openaire +2 more sources
AbstractReaction conditions for numerous exonucleases are detailed in this unit along with discussions of potential applications. Single‐stranded and double‐stranded 5′ => 3′ and 3′ => 5′ exonucleases are included.
openaire +2 more sources
Exonuclease EXD2 in mitochondrial translation
Nature Cell Biology, 2018Elucidating regulation of mitochondrial mRNA translation will improve our understanding of mitochondrial function during homeostasis and disease. Ribonuclease EXD2 is now shown to be important for mitochondrial translation and oxidative phosphorylation, and its loss enhances ROS production, slows development and extends lifespan in flies.
Brian M, Zid, Pankaj, Kapahi
openaire +2 more sources
Biochemistry, 2009
MutS and UvrD proteins individually stimulate Escherichia coli exonuclease VII activity on blunt-ended short duplex DNA substrates. Stimulation by both proteins is ATP-dependent but not mismatch-specific and is not accompanied by apparent strand separation.
Sunil K, Noothi +2 more
openaire +2 more sources
MutS and UvrD proteins individually stimulate Escherichia coli exonuclease VII activity on blunt-ended short duplex DNA substrates. Stimulation by both proteins is ATP-dependent but not mismatch-specific and is not accompanied by apparent strand separation.
Sunil K, Noothi +2 more
openaire +2 more sources
A nuclear 3′–5′ exonuclease proofreads for the exonuclease-deficient DNA polymerase α
DNA Repair, 2002DNA replication is a highly accurate process designed to duplicate the entire genome of a cell during each cell division. The accuracy of DNA replication is derived from the balance between three important components: base selectivity by the replicative DNA polymerases (pols), exonucleolytic proofreading, and post-replicative mismatch repair ...
Kevin R, Brown +3 more
openaire +2 more sources
Journal of Molecular Biology, 1966
Lambda exonuclease was purified 133 times from the hyperactive mutant lysogen, W3350(λ T11 ) and 1000 times from the wild-type lysogen, W3350(λ + ). The following properties of the two enzymes were similar: (1) strong specificity for native DNA; (2) pH optimum; (3) divalent cation requirement; (4) K m ; and (5) inhibition by sodium chloride ...
openaire +1 more source
Lambda exonuclease was purified 133 times from the hyperactive mutant lysogen, W3350(λ T11 ) and 1000 times from the wild-type lysogen, W3350(λ + ). The following properties of the two enzymes were similar: (1) strong specificity for native DNA; (2) pH optimum; (3) divalent cation requirement; (4) K m ; and (5) inhibition by sodium chloride ...
openaire +1 more source