Results 101 to 110 of about 14,025 (272)

Defective Processing of Cytoplasmic and Chloroplast Ribosomal RNA in the Absence of Arabidopsis DXO1

Plant, Cell &Environment, Volume 48, Issue 6, Page 4227-4244, June 2025.
ABSTRACT Decapping 5′‐3′ exoribonucleases from the DXO/Rai1 family are highly conserved among eukaryotes and exhibit diverse enzymatic activities depending on the organism. The biochemical and structural properties of the plant DXO1 differ from the yeast and animal counterparts, which is reflected in the in vivo functions of this enzyme.
Monika Zakrzewska‐Placzek, Anna Golisz‐Mocydlarz, Aleksandra Kwasnik, Michal Krzyszton, Katarzyna Niedzwiecka, Joanna Kufel   +5 more
wiley   +1 more source

A DIStinctively novel exoribonuclease that really likes U

The EMBO Journal, 2013
Regulated degradation plays a major role in determining the levels of both non-coding (miRNA) and coding (mRNA) transcripts. Thus, insights into the factors and pathways that influence this process have broad, interdisciplinary implications. New findings by Malecki et al (2013), Lubas et al (2013), and Chang et al (2013) identify the protein Dis3L2 as ...
Imed E Gallouzi, Jeffrey Wilusz
openaire   +3 more sources

Promotion of Bamboo mosaic virus accumulation in Nicotiana benthamiana by 5’→3’ exonuclease NbXRN4

Frontiers in Microbiology, 2016
Bamboo mosaic virus (BaMV) has a 6.4-kb (+) sense RNA genome with a 5’ cap and a 3’ poly(A) tail. ORF1 of this potexvirus encodes a 155-kDa replication protein responsible for the viral RNA replication/transcription and 5’ cap formation.
Cheng-Cheng eLee, Tzu-Ling eLin, Jhe-Wei eLin, Yu-Tsung eHan, Yu-Ting eHuang, Yau-Heiu eHsu, Menghsiao eMeng   +6 more
doaj   +1 more source

Control of expression of the RNases J1 and J2 in bacillus subtilis [PDF]

, 2014
In Bacillus subtilis, the dual activity 5' exo- and endoribonucleases J1 and J2 are important players in mRNA and stable RNA maturation and degradation. Recent work has improved our understanding of their structure and mechanism of action and identified ...
Hébert, A., Jamalli, A., Putzer, H., Zig, L.   +3 more
core   +1 more source

SAL1‐PAP retrograde signaling orchestrates photosynthetic and extracellular reactive oxygen species for stress responses

The Plant Journal, Volume 122, Issue 5, June 2025.
SUMMARY Cellular responses to abiotic stress involve multiple signals such as reactive oxygen species (ROS), Ca2+, abscisic acid (ABA), and chloroplast‐to‐nucleus retrograde signals such as 3′‐phosphoadenosine 5′‐phosphate (PAP). The mechanism(s) by which these messengers intersect for cell regulation remain enigmatic, as do the roles of retrograde ...
Estee E. Tee, Stephen J. Fairweather, Hanh M. Vo, Chenchen Zhao, Andrew Breakspear, Sachie Kimura, Melanie Carmody, Michael Wrzaczek, Stefan Bröer, Christine Faulkner, Jaakko Kangasjärvi, Zhong‐Hua Chen, Barry J. Pogson, Kai Xun Chan   +13 more
wiley   +1 more source

The 3’-5’ exoribonuclease Dis3 regulates the expression of specific microRNAs in Drosophila wing imaginal discs [PDF]

, 2015
Dis3 is a highly conserved exoribonuclease which degrades RNAs in the 3'-5' direction. Mutations in Dis3 are associated with a number of human cancers including multiple myeloma and acute myeloid leukaemia.
Benjamin P Towler, Cecilia M Arraiano, Christopher I Jones, Joseph A Waldron, Patricia Apura, Sandra C Viegas, Sarah F Newbury, Sarah K Smalley, Sullivan W   +8 more
core   +2 more sources

The enzymatic activity of the nsp14 exoribonuclease is critical for replication of Middle East respiratory syndrome-coronavirus

bioRxiv, 2020
Coronaviruses (CoVs) stand out for their large RNA genome and complex RNA-synthesizing machinery comprising 16 nonstructural proteins (nsps).
N. Ogando, Jessika C. Zevenhoven-Dobbe, C. Posthuma, E. Snijder   +3 more
semanticscholar   +1 more source

In vivo 3′-to-5′ exoribonuclease targetomes of Streptococcus pyogenes [PDF]

Proceedings of the National Academy of Sciences, 2018
Significance To cope with harsh environments and cause infection, bacteria need to constantly adjust gene expression. Ribonucleases (RNases) control the abundance of regulatory and protein-coding RNA through degradation and maturation.
Anaïs Le Rhun, Thibaud T. Renault, Thibaud T. Renault, Anne-Laure Lécrivain, Anne-Laure Lécrivain, Emmanuelle Charpentier, Emmanuelle Charpentier, Karin Hahnke, Rina Ahmed-Begrich   +8 more
openaire   +5 more sources

Yeast RNase III triggers polyadenylation-independent transcription termination [PDF]

, 2009
Transcription termination of messenger RNA (mRNA) is normally achieved by polyadenylation followed by Rat1p-dependent 5'-3' exoribonuleolytic degradation of the downstream transcript.
Abou Elela, Sherif, Gagnon, Jules, Ghazal, Ghada, Jacques, Pierre-Étienne, Landry, Josette-Renée, Robert, François   +5 more
core   +1 more source

RNA processing machineries in Archaea: the 5′-3′ exoribonuclease aRNase J of the β-CASP family is engaged specifically with the helicase ASH-Ski2 and the 3′-5′ exoribonucleolytic RNA exosome machinery

Nucleic Acids Research, 2020
A network of RNA helicases, endoribonucleases and exoribonucleases regulates the quantity and quality of cellular RNAs. To date, mechanistic studies focussed on bacterial and eukaryal systems due to the challenge of identifying the main drivers of RNA ...
D. Phung, Clarisse Etienne, Manon Batista, Petra Langendijk-Genevaux, Y. Moalic, Sébastien Laurent, Sophie Liuu, Violette Morales, M. Jebbar, G. Fichant, M. Bouvier, D. Flament, B. Clouet-d’Orval   +12 more
semanticscholar   +1 more source