Results 91 to 100 of about 182,132 (342)

The role of extracellular vesicles in cutaneous remodeling and hair follicle dynamics [PDF]

open access: yes, 2019
Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are cell-derived membranous structures that were originally catalogued as a way of releasing cellular waste products.
Carrasco, Elisa   +2 more
core   +2 more sources

Exosome Theranostics: Biology and Translational Medicine

open access: yesTheranostics, 2018
Exosomes are common membrane-bound nanovesicles that contain diverse biomolecules, such as lipids, proteins, and nucleic acids. Exosomes are derived from cells through exocytosis, are ingested by target cells, and can transfer biological signals between ...
Chuanjiang He   +3 more
semanticscholar   +1 more source

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

open access: yesAdvanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali   +5 more
wiley   +1 more source

Exosomes maintain cellular homeostasis by excreting harmful DNA from cells

open access: yesNature Communications, 2017
The role of exosomes in intercellular communication is well established, however less in known about the biological roles of exosome secretion in exosome-secreting cells.
Akiko Takahashi   +10 more
doaj   +1 more source

Microencapsulation technology by nature: Cell derived extracellular vesicles with therapeutic potential [PDF]

open access: yes, 2013
Cell derived extracellular vesicles are submicron structures surrounded by phospholipid bilayer and released by both prokaryotic and eukaryotic cells.
Buzás, E., Falus, A., Kittel, Ágnes
core   +1 more source

Role of Pancreatic Stellate Cell-Derived Exosomes in Pancreatic Cancer-Related Diabetes: A Novel Hypothesis [PDF]

open access: gold, 2021
Chamini J. Perera   +7 more
openalex   +1 more source

Challenges and opportunities in exosome research—Perspectives from biology, engineering, and cancer therapy

open access: yesAPL Bioengineering, 2019
Exosomes are small (∼30–140 nm) lipid bilayer-enclosed particles of endosomal origin. They are a subset of extracellular vesicles (EVs) that are secreted by most cell types.
Xia Li   +9 more
semanticscholar   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

open access: yesAdvanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers   +10 more
wiley   +1 more source

Therapeutic potential of mesenchymal stem cell‐derived extracellular vesicles in SARS‐CoV‐2 and H1N1 influenza‐induced acute lung injury

open access: yesJournal of Extracellular Vesicles
Mesenchymal stem cell (MSC)‐derived extracellular vesicles (EVs) have shown anti‐inflammatory potential in multiple inflammatory diseases. In the March 2022 issue of the Journal of Extracellular Vesicles, it was shown that EVs from human MSCs can ...
Jun Ho Lee   +3 more
doaj   +1 more source

RNA Unwinding by the Trf4/Air2/Mtr4 Polyadenylation (TRAMP) Complex [PDF]

open access: yes, 2012
Many RNA-processing events in the cell nucleus involve the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex, which contains the poly(A) polymerase Trf4p, the Zn-knuckle protein Air2p, and the RNA helicase Mtr4p.
Anderson, James T.   +3 more
core   +2 more sources

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