Results 91 to 100 of about 83,398 (334)

Connecting Exosomes and Connexins [PDF]

Cancers, 2019
Intercellular communication is accomplished by passage of ions and small molecules through gap junction channels in directly contacting cells or by secretion and response to transmitters, hormones and extracellular vesicles in cells that are distant from each other.
Joanna Gemel, John Kilkus, Glyn Dawson, Eric C. Beyer   +3 more
openaire   +3 more sources

Multidirectionally Patterned Interdigital Transducers for Enhancing Acoustofluidic Streaming with Flexible Printed Circuit Board

Advanced Functional Materials, EarlyView.
A reconfigurable and multidirectional interdigital transducer (M‐IDT) on a flexible printed circuit board provides a practical platform for acoustofluidic research. It simplifies and accelerates prototyping, enabling cost‐effective exploration of wave modes and fluid dynamics.
Mercedes Stringer, Povilas Dumčius, Xiaoyan Zhang, Yanyan Chai, Ziming Zeng, Zhiqiang Dong, Chao Sun, Dongfang Liang, Guangbo Ge, Yongqing Fu, Zhenlin Wu, Xin Yang   +11 more
wiley   +1 more source

Differential expression of RNA exosome subunits in the amphibian Lithobates catesbeianus during reproductive and non-reproductive periods

BMC Research Notes, 2019
Objective The RNA exosome is an evolutionarily conserved 3′–5′ exoribonucleolytic protein complex involved in processing and degradation of different classes of nuclear and cytoplasmic RNAs, and, therefore, important for the posttranscriptional control ...
J. S. Luz, B. H. Caneguim, A. Baggio, M. M. Santoni, C. C. Helbing, S. R. Valentini, E. Sasso-Cerri, C. C. Oliveira   +7 more
doaj   +1 more source

Controlled Release of Human Dental Pulp Stem Cell‐Derived Exosomes from Hydrogels Attenuates Temporomandibular Joint Osteoarthritis

Advanced Healthcare Materials, EarlyView.
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia, Yajing Tian, Yunzhe Guo, Jiaying Li, Shengjie Cui, Cécile A. Dreiss, Eileen Gentleman, Xuedong Wang   +7 more
wiley   +1 more source

Ovarian Function Restoration with Biomimetic Scaffold Incorporating Angiogenic Molecules and Antioxidant in Chemotherapy‐Induced Perimenopausal Model

Advanced Healthcare Materials, EarlyView.
This study developed a biomimetic scaffold incorporating PDRN and melatonin to restore ovarian function in chemotherapy‐induced premature ovarian insufficiency, enhancing cell survival, folliculogenesis, and hormone normalization, while improving fertility rates and offspring in a mouse model, offering a promising strategy for ovarian function ...
Da‐Seul Kim, Dong Seok Jeong, So‐Yeon Park, Ji‐Won Jung, Jeoung Eun Lee, Jun‐Kyu Lee, Seung‐Woon Baek, Dong Ryul Lee, Dong Keun Han   +8 more
wiley   +1 more source

Advanced Materials for Biological Field‐Effect Transistors (Bio‐FETs) in Precision Healthcare and Biosensing

Advanced Healthcare Materials, EarlyView.
This review explores how advanced materials enhance Bio‐FETs for precision healthcare and biosensing. It covers their working principles, surface functionalization, and ultra‐sensitive detection capabilities. The integration of flexible designs, AI, and IoT for real‐time monitoring is discussed, along with challenges like material reproducibility and ...
Minal Pandey, Manish Bhaiyya, Prakash Rewatkar, Jitendra B. Zalke, Nitin P. Narkhede, Hossam Haick   +5 more
wiley   +1 more source

Extracellular vesicle isolation and counting system (EVics) based on simultaneous tandem tangential flow filtration and large field‐of‐view light scattering

Journal of Extracellular Vesicles
Although the isolation and counting of small extracellular vesicles (sEVs) are essential steps in sEV research, an integrated method with scalability and efficiency has not been developed.
Ju‐Hyun Bae, Chan‐Hyeong Lee, Dokyung Jung, Kyungmoo Yea, Byoung‐Joon Song, Hakho Lee, Moon‐Chang Baek   +6 more
doaj   +1 more source

Tumor‐Targeted Exosome‐Based Heavy Atom‐Free Nanosensitizers With Long‐Lived Excited States for Safe and Effective Sono‐Photodynamic Therapy of Solid Tumors

Advanced Healthcare Materials, EarlyView.
Engineered exosome‐based heavy atom‐free nanosensitizers are developed for safe and targeted sono‐photodynamic therapy of solid tumors. The IR820‐TPE‐loaded, biotin‐conjugated exosomes (IR820‐TPE@B‐Exo) demonstrate significant promise for NIR fluorescence imaging‐guided sono‐photodynamic cancer therapy.
Van‐Nghia Nguyen, Thuy Giang Nguyen Cao, Hyunsun Jeong, Quan Truong Hoang, Binh T. T. Pham, Jieun Bang, Chang Woo Koh, Ji Hee Kang, Jeong Hyun Lee, Xiaofeng Wu, Won Jong Rhee, Young Tag Ko, K. M. K. Swamy, Sungnam Park, JaeHong Park, Min Suk Shim, Juyoung Yoon   +16 more
wiley   +1 more source

The exosome exchange [PDF]

The Journal of Cell Biology, 2007
![][1] Exosomes transport RNA between cells. LOTVALL/MACMILLAN Cells send RNA messages to each other by packing them into tiny membrane vesicles called exosomes, according to Hadi Valadi, Jan Lotvall (Goteborg University, Goteborg, Sweden), and colleagues.
openaire   +1 more source

High‐Yield Bioproduction of Extracellular Vesicles from Stem Cell Spheroids via Millifluidic Vortex Transport

Advanced Materials, EarlyView.
Stem cell spheroids, produced via a high‐throughput microfabrication technique, are transported within a vortex generated at the outlet channels of a cross‐slot millifluidic chip. For Reynolds number exceeding 170–200, intermittent high shear stresses applied to each spheroid within the vortex trigger a massive release of biologically active ...
Elliot Thouvenot, Laura Charnay, Noa Burshtein, Jean‐Michel Guigner, Léonie Dec, Damarys Loew, Amanda K.A. Silva, Anke Lindner, Claire Wilhelm   +8 more
wiley   +1 more source