Results 91 to 100 of about 94,365 (207)

Exosome mimetics: a novel class of drug delivery systems

, 2012
Sander AA Kooijmans, Pieter Vader, Susan M van Dommelen, Wouter W van Solinge, Raymond M SchiffelersDepartment of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The NetherlandsAbstract: The identification of extracellular
van Solinge, WW, Kooijmans, SA, van Dommelen, SM, Kooijmans SAA, Vader P, van Dommelen SM, van Solinge WW, Schiffelers, RM, Schiffelers RM, Vader, Pieter, Vader, P   +10 more
core   +1 more source

Downregulation of exosomal miR-192-5p and miR-204-5p in subjects with nonclassic apparent mineralocorticoid excess

Journal of Translational Medicine, 2019
Background The “nonclassic” apparent mineralocorticoid excess (NC-AME) has been identified in approximately 7% of general population. This phenotype is characterized by low plasma renin activity (PRA), high serum cortisol (F) to cortisone (E) ratio, low ...
Alejandra Tapia-Castillo, Dominic Guanzon, Carlos Palma, Andrew Lai, Eric Barros, Fidel Allende, Andrea Vecchiola, Carlos E. Fardella, Carlos Salomón, Cristian A. Carvajal   +9 more
doaj   +1 more source

Coconut milk exosomal formulation of curcumin analog targets head and neck cancer progression through alterations in the HABP1 signaling mechanism

Cancer Treatment and Research Communications
Background: Head and neck cancer (HNC) is a malignancy characterized by uncontrolled cell growth with increasing incidence rates and heterogeneity. Hyaluronan binding protein 1 (HABP1) is a glycoprotein that acts as a cell surface marker, influencing the
Kaumudi Pande, Bettadaiah B K, Anbarasu Kannan   +2 more
doaj   +1 more source

Reply to ‘Sulfisoxazole does not inhibit the secretion of small extracellular vesicles’

Nature Communications, 2021
Chan-Hyeong Lee, Ju-Hyeon Bae, Jong-In Kim, Ju-Mi Park, Eun-Ji Choi, Moon-Chang Baek   +5 more
doaj   +1 more source

Exosome-Coated Prussian Blue Nanoparticles for Specific Targeting and Treatment of Glioblastoma

Glioblastoma is one of the most aggressive and invasive types of brain cancer with a 5-year survival rate of 6.8%. With limited options, patients often have poor quality of life and are moved to palliative care after diagnosis.
Seock-Jin Chung (9570136), Kay Hadrick (18309783), Taeho Kim (1275954), Md Nafiujjaman (1918939), Panangattukara Prabhakaran Praveen Kumar (18339857), Meghan L. Hill (18339851), Cho Rong Park (11253450), Hyun-Joo Woo (18339854), Leila Mwangi (18339860), Rachna Parikh (18339863)   +9 more
core   +1 more source

Exosomes and Exosome-Mimetics for Atopic Dermatitis Therapy

Tissue Engineering and Regenerative Medicine
Exosomes and exosome mimetics are used as alternatives to cell therapy. They have shown potential in treating skin disorders by fortifying the skin barrier, mediating angiogenesis, and regulating the immune response while minimizing side effects. Currently, numerous studies have applied exosome therapy to treat atopic dermatitis (AD) caused by a ...
Jae Hoon Kim, Ju-El Kim, Seong-Jun Kang, Jeong-Kee Yoon   +3 more
openaire   +3 more sources

Differential expression of RNA exosome subunits in the amphibian Lithobates catesbeianus during reproductive and non-reproductive periods

BMC Research Notes, 2019
Objective The RNA exosome is an evolutionarily conserved 3′–5′ exoribonucleolytic protein complex involved in processing and degradation of different classes of nuclear and cytoplasmic RNAs, and, therefore, important for the posttranscriptional control ...
J. S. Luz, B. H. Caneguim, A. Baggio, M. M. Santoni, C. C. Helbing, S. R. Valentini, E. Sasso-Cerri, C. C. Oliveira   +7 more
doaj   +1 more source

Exosomes Extraction and Identification

, 2019
Exosomes are small endosome-derived lipid nanoparticles (50-120 nm in diameter), actively secreted by exocytosis in most living cells. Recently, there is a growing interest of research focused on studying the exosome functions and to understand ways to use them for therapeutic applications in a wide variety of disorders, such as cancer, cardiovascular,
Wu, Xiaoxin, Showiheen, Salah Ali A, Sun, Antonia Rujia, Crawford, Ross, Xiao, Yin, Mao, Xinzhan, Prasadam, Indira   +6 more
openaire   +5 more sources

Multidimensional Effects of Stress on Neuronal Exosome Levels and Simultaneous Transcriptomic Profiles

Biological Psychiatry Global Open Science
Background: An excess of exosomes, nanovesicles released from all cells and key regulators of brain plasticity, is an emerging therapeutic target for stress-related mental illnesses.
Hope Kronman, Amarjyot Singh, Shofiul Azam, Andrea S. Guzman, Danielle Zelli, Timothy Lau, Josh Dobbin, Benedetta Bigio, Carla Nasca   +8 more
doaj   +1 more source

Tumor-homing exosomes enable targeted delivery of siRNA and isoimperatorin for overcoming BTK inhibitor resistance in DLBCL

Materials Today Bio
Diffuse large B-cell lymphoma (DLBCL) is the most common type of lymphoma, but over one-third of patients relapse or develop refractory disease after first-line therapy. Novel therapeutic strategies are required to address persistent unmet clinical needs
Ruowen Sun, Yanchao Yang, Bin Zhang, Jiayuan Chen, Ye Wang, Zehui Jiang, Linlin Zhang, Milad Ashrafizadeh, Gautam Sethi, Jing Shen, Zuofei Chi   +10 more
doaj   +1 more source