Results 261 to 270 of about 6,729,673 (335)

Exosomes-loaded with traditional Chinese medicine constituents: a novel therapeutic avenue for aplastic anemia. [PDF]

Chin Med
Zhang GK, Zhou F.
europepmc   +1 more source

Versatile DNA Hydrogel‐Mediated Delivery of Ginsenoside‐Encapsulated Small Extracellular Vesicles to Boost Diabetic Wound Repair

Advanced Science, EarlyView.
This study presents a DNA hydrogel‐mediated delivery system, in which ginsenoside (GS) molecules are incorporated into small extracellular vesicles (sEV) secreted by mesenchymal stem cells (MSCs) and the formed complexes are then anchored in DNA hydrogels via aptamer‐CD63 affinity as “GS/sEV@DNAgels”, to improve diabetic wound repair.
Jianming Xing, Shuangyang Li, Yuning Wang, Xushuang Jia, Ruiting Lin, Xintong Liu, Dongxu Wang, Ning Cui, Peng Ji, Jiaqi Chen, Shengnian Wang, Guangzhe Li, Ye Teng, Da Liu, Ye Jin   +14 more
wiley   +1 more source

Exosomes in Autoimmunity: Mediators of Autoantigen Presentation and Targets for Therapeutic Intervention in Autoimmune Diseases. [PDF]

J Clin Immunol
Almohaimeed HM, Almars AI, Tounsi WA, Mohammedsaleh ZM, Panigrahi R, Singh I, Singh S, Dhara B, Uti DE.   +8 more
europepmc   +1 more source

Nuclear exosome targeting complex safeguards hematopoietic stem cell self-renewal and genomic integrity through resolving R loops

Yinghao Pan, Hongna Zuo, Xiao-Fei Yan, Jiali Li, Yuwen Li, Jin Li, You Wu, Liquan Hong, Mingwei Wang, Aiwei Wu, Zhenyu Ju, Yawei Gao, Hu Wang   +12 more
openalex   +1 more source

Engineered Bacteria‐Vesicle Delivered Lactate Reprogramming Boosts Tumor Radiosensitivity

Advanced Science, EarlyView.
We engineered a bacterial‐vesicular dual‐delivery platform that targets LOx to colorectal tumors, enabling lactate clearance, immune microenvironment remodeling, and microbiota modulation. This microbe–metabolism synergistic strategy effectively sensitizes colorectal cancer to radiotherapy, offering a promising approach to overcome radioresistance ...
Fei Peng, Zhe Lei, Zhehao Zhang, Zhiyue Su, Chonghai Zhang, Huan Yang, Shu Liu, Mengyuan Hu, Yuhong Wang, Lingchuan Guo, Lin Hu, Kai Yang   +11 more
wiley   +1 more source

From CAR-T Cells to Exosome-Based Immunotherapy: Exploring the Frontiers of Cell-Free Targeted Cancer Therapeutics. [PDF]

Cells
Tîrziu A, Bojin FM, Gavriliuc OI, Faur CI, Păunescu V.   +4 more
europepmc   +1 more source

AI‐Enhanced Surface‐Enhanced Raman Scattering for Accurate and Sensitive Biomedical Sensing

Advanced Intelligent Discovery, EarlyView.
AI‐SERS advances spectral interpretation with greater precision and speed, enhancing molecular detection, biomedical analysis, and imaging. This review explores its essential contributions to biofluid analysis, disease identification, therapeutic agent evaluation, and high‐resolution biomedical imaging, aiding diagnostic decision‐making.
Seungki Lee, Rowoon Park, Ho Sang Jung
wiley   +1 more source

Systematic Mining of Bioactive Compounds for Wound Healing From <i>Cayratia Japonica</i> Exosome-Like Nanovesicles: A Workflow Combining LC-MS and DeepSeek Models. [PDF]

JMIR Bioinform Biotechnol
Fu Q, Ji W, Fan YP, Yao J, Song MX, Yan QJ.   +5 more
europepmc   +1 more source

Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex

Cell, 2018
Eva-Maria Weick, M. Puno, K. Januszyk, J. C. Zinder, M. DiMattia, Christopher D. Lima   +5 more
semanticscholar   +1 more source

A Solution for Exosome‐Based Analysis: Surface‐Enhanced Raman Spectroscopy and Artificial Intelligence

Advanced Intelligent Discovery, EarlyView.
Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz, Zakarya Al‐Shaebi, Omer Aydin   +2 more
wiley   +1 more source