Results 311 to 320 of about 6,729,673 (335)

Decoding the exosomal nucleic acid delivery system axis of macrophage autophagy and immune reprogramming via multi-omics analysis. [PDF]

Front Mol Biosci
Zhu Z, Xiang W, Zhang P, Yasin P, Song X.   +4 more
europepmc   +1 more source

A screening strategy based on machine learning for diagnostic biomarkers in small cell lung cancer. [PDF]

PLoS One
Pan Y, Ding X, Duan W, Wang L, Dai Y, Han R, Wang S, Guo M.   +7 more
europepmc   +1 more source

Libération extra-cellulaire de microARN et de complexes nucléo-protéiques par les cellules infectées par EBV : rôle des exosomes et d’autres transporteurs

, 2011
Claire Gourzonès
openalex   +1 more source

Noncoding RNAs in chronic wound healing: Mechanisms, exosome therapeutics, and translational frontiers. [PDF]

J Tissue Eng
Yang L, Lv Y.
europepmc   +1 more source

Nuclear effects play an important role in determining codon usage-dependent human gene expression. [PDF]

Nat Commun
Garg R, Xie P, Duan J, Liu H, Liu Y.
europepmc   +1 more source

Extra-cellular release of microRNA and nucleoprotein complexes by malignant cells infected by EBV : role of exosomes and other carriers

, 2011
Claire Gourzonès, BUSSON, Pierre
openalex   +1 more source

The regulation and functions of the nuclear RNA exosome complex [PDF]

Nature Reviews Molecular Cell Biology, 2016
The RNA exosome complex is the most versatile RNA-degradation machine in eukaryotes. The exosome has a central role in several aspects of RNA biogenesis, including RNA maturation and surveillance. Moreover, it is emerging as an important player in regulating the expression levels of specific mRNAs in response to environmental cues and during cell ...
Cornelia Kilchert, Sina Wittmann, L. Vasiljeva   +2 more
semanticscholar   +3 more sources

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APE1 interacts with the nuclear exosome complex protein MTR4 and is involved in cisplatin‐ and 5‐fluorouracil‐induced RNA damage response

The FEBS Journal, 2022
The nuclear RNA surveillance mechanism is essential for cancer cell survival and is ensured by the RNA nuclear exosome including some co‐factors, such as the RNA helicase MTR4. Recent studies suggest an involvement of DNA repair proteins such as apurinic/
Marta Codrich, Monica Degrassi, M. Malfatti, G. Antoniali, A. Gorassini, D. Ayyildiz, Rossella De Marco, G. Verardo, G. Tell   +8 more
semanticscholar   +1 more source

NMR studies of the archaeal exosome complex

, 2016
This study is about structural studies of the exosome from Sulfolobus solfataricus. It includes dynamics analysis (by using Nuclear Magnetic Resonance) of the complex in absence and in presence of RNA. Additional biochemical experiments (degradation assays, fluorescence anisotropy) allowed further description of the interaction exosome-RNA.
Maxime Audin
semanticscholar   +4 more sources

RNA degradation paths in a 12-subunit nuclear exosome complex

Nature, 2015
The eukaryotic exosome is a conserved RNA-degrading complex that functions in RNA surveillance, turnover and processing. How the same machinery can either completely degrade or precisely trim RNA substrates has long remained unexplained. Here we report the crystal structures of a yeast nuclear exosome containing the 9-subunit core, the 3'-5' RNases ...
D. Makino, B. Schuch, Elisabeth Stegmann, M. Baumgärtner, C. Basquin, E. Conti   +5 more
semanticscholar   +4 more sources