Results 91 to 100 of about 147,911 (307)

Emerging Role of Exosomes in the Joint Diseases

open access: yesCellular Physiology and Biochemistry, 2018
Exosomes are a subset of small, membrane-bound extracellular vesicles that are important for communication among cells. They originate from the cell membrane during endocytic internalization, and are stable in biological fluids, including blood and ...
Zeng Li   +5 more
doaj   +1 more source

Additional file 2 of Aerobic exercise improves cognitive impairment in mice with type 2 diabetes by regulating the MALAT1/miR-382-3p/BDNF signaling pathway in serum-exosomes

open access: yes, 2023
Additional file 2: Fig. S2. Schematic diagram illustrating the molecular mechanism of aerobic exercise improving cognitive impairment in T2DM mice by regulating the MALAT1/miR-382-3p/BDNF signaling pathway in serum ...
Wenping Gu (7057562)   +6 more
core   +1 more source

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

open access: yesAdvanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang   +12 more
wiley   +1 more source

Intercellular communication via exosomes [PDF]

open access: yes, 2012
Exosomes are small membrane bound vesicles between 30-100 nm in diameter of endocytic origin that are secreted into the extracellular environment by many different cell types.
Valadi Hadi   +16 more
core   +2 more sources

Circulating exosomes secreted by osteosarcoma cells are potential biomarkers for metastasis

open access: yes, 2021
Selva, Erica M.Sampson, ValerieOsteosarcoma is a primary malignant bone tumor found in children and is the third most common cancer in children and adolescents.
Jeshurin, Madeline
core   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

open access: yesAdvanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale   +6 more
wiley   +1 more source

Exosomal Epigenetics

open access: yesEMBnet.journal
Epigenetics is the study of heritable changes in gene expression that occur without changes to the underlying DNA sequence. Epigenetic modifications can include DNA methylation, histone modifications, and non-coding RNAs, among others. These modifications can influence the expression of genes by altering the way DNA is packaged and accessed by ...
Papakonstantinou, Eleni   +3 more
openaire   +2 more sources

Salivary exosomes as potential biomarkers in cancer

open access: yes, 2018
Over the past decade, there has been emerging research in the field of extracellular vesicles, especially those originating from endosomes, referred to as 'exosomes.
Kenny, Liz   +3 more
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

Lipidomics and biodistribution of extracellular vesicles‐secreted by hepatocytes from Zucker lean and fatty rats

open access: yesJournal of Extracellular Biology
Extracellular vesicles (EVs) have been involved in metabolic syndrome, although their specific role in the development of the pathology is still unknown.
Maria Azparren‐Angulo   +12 more
doaj   +1 more source

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