Results 121 to 130 of about 202,955 (306)
Theranostics, 2021 Rationale: Breast cancer preferentially develops osteolytic bone metastasis, which makes patients suffer from pain, fractures and spinal cord compression.
Xinxin Yuan +27 more
semanticscholar +1 more source
Development of Stable Cell Lines for the Production of Hematopoietic Stem Cell Targeted Exosomes [PDF]
, 2018 Exosomes represent a promising new approach to targeted drug delivery. Current research explores the ability of these naturally occurring nanoparticles to transport therapeutic cargo to specific tissues of the body and to subsequently enter the cells of ...
Beard, Anja, Ehlinger, Zach
core +1 more source
Profiling of RNAs from Human Islet-Derived Exosomes in a Model of Type 1 Diabetes [PDF]
, 2019 Type 1 diabetes (T1D) is characterized by the immune-mediated destruction of insulin-producing islet β cells. Biomarkers capable of identifying T1D risk and dissecting disease-related heterogeneity represent an unmet clinical need.
Evans-Molina, Carmella +4 more
core +1 more source
Annals of Hepatology, 2021 Introduction: Alcohol abuse has a high impact on the mortality and morbidity related to a great number of diseases and is responsible for the development of alcoholic liver disease (ALD).
E. Gonzalez +6 more
doaj
Journal of Nanobiotechnology, 2023 Oral and maxillofacial diseases are one of the most prevalent diseases in the world, which not only seriously affect the health of patients’ oral and maxillofacial tissues, but also bring serious economic and psychological burdens to patients. Therefore,
Jianing Ren +10 more
doaj +1 more source
TLR-exosomes exhibit distinct kinetics and effector function [PDF]
arXiv, 2016 The innate immune system is vital to rapidly responding to pathogens and Toll-like receptors (TLRs) are a critical component of this response. Nanovesicular exosomes play a role in immunity, but to date their exact contribution to the dissemination of the TLR response is unknown.
arxiv
Molecular Cancer, 2019 Cancer associated fibroblasts (CAFs) are key stroma cells that play dominant roles in tumor progression. However, the CAFs-derived molecular determinants that regulate colorectal cancer (CRC) metastasis and chemoresistance have not been fully ...
J. L. Hu +12 more
semanticscholar +1 more source
Tetherin is an exosomal tether
eLife, 2016 Exosomes are extracellular vesicles that are released when endosomes fuse with the plasma membrane. They have been implicated in various functions in both health and disease, including intercellular communication, antigen presentation, prion transmission, and tumour cell metastasis.
Edgar, James R +4 more
openaire +7 more sources
Exosomes promote pre-metastatic niche formation in ovarian cancer. [PDF]
, 2019 Ovarian cancer is one of the most common gynecological malignancies. Upon initial diagnosis, the majority of patients present with widespread metastatic growth within the peritoneal cavity. This metastatic growth occurs in stages, with the formation of a
Dean, Dylan C +4 more
core +2 more sources
The biology and function of exosomes in cancer.
Journal of Clinical Investigation, 2016 Humans circulate quadrillions of exosomes at all times. Exosomes are a class of extracellular vesicles released by all cells, with a size range of 40-150 nm and a lipid bilayer membrane. Exosomes contain DNA, RNA, and proteins.
R. Kalluri
semanticscholar +1 more source