Results 141 to 150 of about 186,133 (340)

Exosomal Epigenetics

open access: yesEMBnet.journal
Epigenetics is the study of heritable changes in gene expression that occur without changes to the underlying DNA sequence. Epigenetic modifications can include DNA methylation, histone modifications, and non-coding RNAs, among others. These modifications can influence the expression of genes by altering the way DNA is packaged and accessed by ...
Papakonstantinou, Eleni   +3 more
openaire   +2 more sources

Porous Decellularized Nerve Grafts Facilitate Recellularization and Nerve Regeneration in a Rat Model of Critical Long‐Gap Peripheral Nerve Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
A decellularized nerve graft (DNG) is modified to generate a porous DNG (PDNG). The PDNG is used to repair a 30‐mm peripheral nerve injury (PNI) defect, and is compared with isograft, serving as the standard, and DNG, a widely used alternative. The result shows that PDNG facilitated nerve regeneration in long‐gap PNI, evidenced by better‐aligned axonal
Olawale Alimi Alimi   +10 more
wiley   +1 more source

Exosome membrane bound TNF-receptor for the treatment of rheumatoid arthritis [PDF]

open access: yes, 2017
Rheumatoid arthritis (RA) is an autoimmune disease that causes painful inflammation of the synovium of the patient’s joints. However, current treatments for RA have a variety of drawbacks.
Curley, Kevin, Duong, Natalie
core   +1 more source

RNA surveillance and the exosome [PDF]

open access: yesRNA, 2015
The discoveries that have had the greatest effect on my work over the past 20 years relate to the nuclear RNA surveillance systems, particularly the exosome complex and its cofactors in budding yeast. These insights were made possible, in large part, by technical progress; in the fields of proteomics, genetics, structural biology, high-throughput ...
openaire   +3 more sources

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

open access: yesAdvanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang   +3 more
wiley   +1 more source

Exosomes in Cardiovascular Medicine [PDF]

open access: yesCardiology and Therapy, 2017
Exosomes are small, extracellular membrane-bound particles that mediate intercellular transport of a cytosolic cargo. Exosomal transfer of micro-RNA can modify gene expression in targeted cells. Exosome-based endocrine/paracrine signaling has been shown to be involved in a wide range of physiological processes including those associated with ...
openaire   +4 more sources

Photonic Nanomaterials for Wearable Health Solutions

open access: yesAdvanced Materials, EarlyView.
This review discusses the fundamentals and applications of photonic nanomaterials in wearable health technologies. It covers light‐matter interactions, synthesis, and functionalization strategies, device assembly, and sensing capabilities. Applications include skin patches and contact lenses for diagnostics and therapy. Future perspectives emphasize AI‐
Taewoong Park   +3 more
wiley   +1 more source

Therapeutic application of mesenchymal stem cell-derived exosomes in skin wound healing

open access: yesFrontiers in Bioengineering and Biotechnology
Wound healing is a complicated obstacle, especially for chronic wounds. Mesenchymal stem cell-derived exosomes may be a promising cell-free approach for treating skin wound healing.
Yunhan Sun   +10 more
doaj   +1 more source

Autoantibodies directed to novel components of the PM/Scl complex, the human exosome [PDF]

open access: gold, 2001
Rick Brouwer   +10 more
openalex   +1 more source

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