Results 161 to 170 of about 202,955 (306)
RNA surveillance and the exosome [PDF]
The discoveries that have had the greatest effect on my work over the past 20 years relate to the nuclear RNA surveillance systems, particularly the exosome complex and its cofactors in budding yeast. These insights were made possible, in large part, by technical progress; in the fields of proteomics, genetics, structural biology, high-throughput ...
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Label-free detection of exosomes from different cellular sources based on surface-enhanced Raman spectroscopy combined with machine learning models [PDF]
Exosomes are significant facilitators of inter-cellular communication that can unveil cell-cell interactions, signaling pathways, regulatory mechanisms and disease diagnostics. Nonetheless, current analysis required large amount of data for exosome identification that it hampers efficient and timely mechanism study and diagnostics.
arxiv
Engineering exosomes as refined biological nanoplatforms for drug delivery
Exosomes, a subgroup of extracellular vesicles (EVs), have been recognized as important mediators of long distance intercellular communication and are involved in a diverse range of biological processes.
Xin Luan+5 more
semanticscholar +1 more source
Microvesicles as vehicles for tissue regeneration: Changing of the guards [PDF]
Purpose of Review: Microvesicles (MVs) have been recognised as mediators of stem cell function, enabling and guiding their regenerative effects. Recent Findings: MVs constitute one unique size class of extracellular vesicles (EVs) directly shed from ...
Davies, R. Wayne+3 more
core +1 more source
Degradation of ribosomal RNA precursors by the exosome [PDF]
Christine Allmang
openalex +1 more source
Epigenetics is the study of heritable changes in gene expression that occur without changes to the underlying DNA sequence. Epigenetic modifications can include DNA methylation, histone modifications, and non-coding RNAs, among others. These modifications can influence the expression of genes by altering the way DNA is packaged and accessed by ...
Papakonstantinou, Eleni+3 more
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Exosomes in Cardiovascular Medicine [PDF]
Exosomes are small, extracellular membrane-bound particles that mediate intercellular transport of a cytosolic cargo. Exosomal transfer of micro-RNA can modify gene expression in targeted cells. Exosome-based endocrine/paracrine signaling has been shown to be involved in a wide range of physiological processes including those associated with ...
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Exosome membrane bound TNF-receptor for the treatment of rheumatoid arthritis [PDF]
Rheumatoid arthritis (RA) is an autoimmune disease that causes painful inflammation of the synovium of the patient’s joints. However, current treatments for RA have a variety of drawbacks.
Curley, Kevin, Duong, Natalie
core +1 more source
Les exosomes dérivés des cellules dendritiques [PDF]
Sebastián Amigorena
openalex +1 more source
Exosomes are nanometre-size vesicles manufactured within late multi-vesicular endosomes and actively secreted into the extracellular environment [...]
Clayton, A., Mason, M.D.
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