Results 161 to 170 of about 186,133 (340)

Arabidopsis thaliana exosome subunit AtRrp4p is a hydrolytic 3'->5' exonuclease containing S1 and KH RNA-binding domains [PDF]

, 2002
Julia A. Chekanova
openalex   +1 more source

Biomimetic Cell Membrane‐Coated Scaffolds for Enhanced Tissue Regeneration

Advanced Materials, EarlyView.
This review examines the development and use of cell membrane‐coated scaffolds in tissue engineering. Bioinspired phospholipid and glycocalyx coatings enhance anti‐fouling, anti‐thrombogenic, and selective molecular recognition properties. Native cell membrane coatings further support cell‐specific interactions, immune modulation, and reduced bacterial
Carmen Alvarez‐Lorenzo, Alejandro Ramirez‐Romero, Diana Peixoto, Maria Vivero‐Lopez, Isabel Rodríguez‐Moldes, Angel Concheiro   +5 more
wiley   +1 more source

A SERS‐Based Antibody‐Aptamer Sandwich Assay for Extracellular Vesicle‐Associated Tau Detection Using Gold Nanoparticles

Advanced Sensor Research, EarlyView.
Tau protein plays a critical role in the pathology of Alzheimer's disease, utilizing extracellular vesicles (EVs) as a mechanism for intercellular transmission. This study develops a highly sensitive sandwich assay biosensor for detecting and quantifying tau‐associated EVs using surface‐enhanced Raman spectroscopy (SERS).
Saqer Al Abdullah, Samaneh Ghadami, Md. Arifur Rahman Khan, Farbod Ebrahimi, Kyle Nowlin, Tetyana Ignatova, Kristen Dellinger   +6 more
wiley   +1 more source

Assessing Neuronal and Astrocyte Derived Exosomes From Individuals With Mild Traumatic Brain Injury for Markers of Neurodegeneration and Cytotoxic Activity. [PDF]

, 2019
Mild traumatic brain injury (mTBI) disproportionately affects military service members and is very difficult to diagnose. To-date, there is currently no blood-based, diagnostic biomarker for mTBI cases with persistent post concussive symptoms. To examine
Baker, Dewleen G, Campana, Wendy, Conger, Tori, Ellisman, Maya, Hall, James R, Julovich, David A, Nauss, Sophie, Nievergelt, Caroline M, O'Bryant, Sid E, Risbrough, Victoria B, Rissman, Robert A, Romero, Haylie K, Winston, Charisse N   +12 more
core  

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

Advanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen   +7 more
wiley   +1 more source

The Biogenesis and Functions of Exosomes [PDF]

, 2002
Willem Stoorvogel, Monique J. Kleijmeer, Hans J. Geuze, Graça Raposo   +3 more
openalex   +1 more source

Cytokine mRNA Delivery and Local Immunomodulation in the Placenta Using Lipid Nanoparticles

Advanced Therapeutics, EarlyView.
This article evaluates lipid nanoparticles to deliver immunomodulatory mRNA to placental cells and mouse placentas to study and treat the immune underpinnings of placenta‐related diseases. Lipid nanoparticles induce cytokine secretion and macrophage polarization toward an anti‐inflammatory state.
Samuel I. Hofbauer, Luisa A. Fink, Rachel E. Young, Tara Vijayakumar, Katherine M. Nelson, Nia Bellopede, Mohamad‐Gabriel Alameh, Drew Weissman, Jason P. Gleghorn, Rachel S. Riley   +9 more
wiley   +1 more source

Processing of 3′-Extended Read-Through Transcripts by the Exosome Can Generate Functional mRNAs [PDF]

, 2002
Claire Torchet, Cécile Bousquet‐Antonelli, Laura Milligan, Emma Thompson, Joanna Kufel, David Tollervey   +5 more
openalex   +1 more source

Exploring AAV‐Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential

Advanced Science, EarlyView.
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu, Wuhui He, Yun Xiao, Qiong Wu, Qing Zhang, Tiesong Zhang, Lei Xu, Xinyi Pang   +7 more
wiley   +1 more source

A New Strategy to Functionalize Exosomes via Enzymatic Engineering of Surface Glycans and its Application to Profile Exosomal Glycans and Endocytosis

Advanced Science
Exosomes are membrane‐enclosed nanoparticles secreted by cells to mediate intercellular communication. Hence, functionalized exosomes are powerful tools in biology and medicine, and efficient methods to functionalize exosomes are highly desired.
Sayan Kundu, Jiatong Guo, Md. Shamiul Islam, Rajendra Rohokale, Mohit Jaiswal, Zhongwu Guo   +5 more
doaj   +1 more source