Results 231 to 240 of about 115,777 (264)
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Exosomes in preeclampsia

Clinica Chimica Acta
Preeclampsia (PE) is a multifactorial pregnancy disorder marked by new-onset hypertension after 20 weeks of gestation, often accompanied by proteinuria or organ dysfunction. Affecting 4-6 % of pregnancies globally, PE remains a leading cause of maternal and fetal morbidity. While its precise etiology is not fully understood, growing evidence implicates
Asma, Vafadar   +5 more
openaire   +2 more sources

Exosomes in erythropoiesis

Transfusion Clinique et Biologique, 2010
Multivesicular endosomes contain membrane vesicles which can be released into the extracellular environment as exosomes. This review describes the role of exosome secretion in the remodeling of the red cell plasma membrane during the last stage of erythropoietic differentiation. Herein, we propose that the exosome biogenesis involves several mechanisms
openaire   +3 more sources

Exosomes in Critical Illness

Critical Care Medicine, 2017
Objective: Exosomes are small, cell-released vesicles (40–100 nm in size) with the potential to transfer proteins, lipids, small RNAs, messenger RNAs, or DNA between cells via interstitial fluids. Due to their role in tissue homeostasis, exosomes have emerged as a new type of therapeutic and diagnostic (theranostic) tool in the
TERRASINI, NORA, LIONETTI, Vincenzo
openaire   +2 more sources

The Role of Exosomes and Exosome-derived microRNAs in Atherosclerosis

Current Pharmaceutical Design, 2018
Atherosclerosis is the leading cause of death and morbidity throughout industrialized nations, accounting for one-fifth of all deaths globally. Exosomes are bi-lipid membranous vesicles containing protein, lipid and nucleic acid contents that are released from the cells via the endolysosomal pathway.
openaire   +2 more sources

The Human Exosome and Disease

2010
Long before the RNA degrading exosome was first described in the yeast Saccharomyces cerevisiae, the use of autoantibodies found in the sera of certain autoimmune patients allowed the identification of a complex of polypeptides which later appeared to be the human exosome.
Staals, R.H.J., Pruijn, G.J.M.
openaire   +4 more sources

The Archaeal Exosome

2010
The archaeal exosome is aprotein complex with structural similarities to the eukaryotic exosome and bacterial PNPase. Its catalytic core is formed by alternating Rrp41 and Rrp42 polypeptides, arranged in a hexameric ring. A flexible RNA binding cap composed of the evolutionarily conserved proteins Rrp4 and/or Cs14 is bound at the top of the ring and ...
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Exosomes

Nature Biotechnology, 2020
openaire   +2 more sources

Engineered exosomes for studies in tumor immunology

Immunological Reviews, 2022
Ahmet Alptekin   +2 more
exaly  

Tumor-derived exosomes in the regulation of macrophage polarization

Inflammation Research, 2020
Mírzá Baig   +2 more
exaly  

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