Results 241 to 250 of about 176,486 (297)

CCL26‐Mediated Modulation of Endothelial Secretome by Hypoxia‐Induced Tumor‐Derived Exosomes Enhances Metastatic Progression in Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Tumor cells adapt to hypoxia by releasing hiTDExs enriched with bioactive molecules that modulate endothelial behavior and promote tumor progression. This study aimed to characterize how hypoxia‐induced HNSCC exosomes reshape the endothelial secretome and contribute to metastatic potential.
Ozel Capik, Sevil Tekman, Betul Gundogdu, Ahsen Kilic, Rumeysa Polat, Omer Aydin, Omer Faruk Karatas   +6 more
wiley   +1 more source

7SK-enriched exosomes suppress the cancer phenotypes in human lung cancer cells: insights from 2D and microfluidic 3D in vitro models. [PDF]

Sci Rep
Aghamiri S, Ajoudanian M, Farhadi S, Sharifi K, Ghanbarian H.   +4 more
europepmc   +1 more source

Physical Changes of Biomacromolecules upon Covalent Surface Immobilization. [PDF]

Langmuir
Mercado Velez B, Sharma V, Kriz S, Freitas ETF, Goetsch P, Heldt CL.   +5 more
europepmc   +1 more source

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

International Journal of Cancer, EarlyView.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon, Min‐Kyung Lee, Eunyong Ahn, Heeyeon Kim, Yong Sang Song, Taejin Ahn   +5 more
wiley   +1 more source

Exosome-based vaccines in cancer immunotherapy: antitumor mechanisms, engineering strategies, and challenges. [PDF]

J Cancer Res Clin Oncol
Zhou H, Shi Y, Wang Y, Bai G.
europepmc   +1 more source

Multidisciplinary Strategies for Targeting Tumor Dormancy in Breast Cancer Therapeutics: Hallmarks, Mechanism, and Approaches

iMetaMed, EarlyView.
Clinical phases and classification of breast tumor dormancy. Tumor dormancy is described as the period after treatment until residual tumor cells become detectable as relapsing disease in clinic. During the period of clinical tumor dormancy, tumor mass dormancy and cellular dormancy may coexist.
Shu Chen, Hui Chen, Vijaya Raghavan, Jing Huang, Jin Wang   +4 more
wiley   +1 more source

Lipid Membrane-Coated Nanopipettes for Enhanced Resistive Pulse Sensing of Exosomes. [PDF]

ACS Appl Mater Interfaces
Hiramoto K, Kaji C, Hirano-Iwata A.
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Exosomes as Pivotal Mediators of Tumor-Immune Communication: Implications for Immunotherapy and Liquid Biopsy. [PDF]

Int J Nanomedicine
Wei M, Wang D, Xu W, Zang X, Jiang J.
europepmc   +1 more source

Extracellular Vesicles Associated Metabolites as Intercellular Signalling Mediators in Disease and Therapy. [PDF]

Metabolites
Qadeer A, Ullah A, Khan MZ, Alsharif KF, Alzahrani FM, Alzahrani KJ, Abuderman AA, Abuderman AA.   +7 more
europepmc   +1 more source