Results 51 to 60 of about 441,134 (194)

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi   +6 more
wiley   +1 more source

Un éveil de la seconde nature ? La Deutung de l’histoire chez le jeune Adorno

open access: yesAstérion, 2010
Ce travail opère une relecture de deux textes de jeunesse de Th. W. Adorno dans l’optique d’une réévaluation de leur importance pour son œuvre ultérieure, en particulier pour sa philosophie de l’histoire.
Florian Nicodème
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Sémiotique de l’expérience : la médiation entre réalité et langage. À propos de la réalité dans l’œuvre de Jean-Claude Coquet

open access: yesActes Sémiotiques
Jean-Claude Coquet distingue phusis et logos, le passage de l’une à l’autre étant assuré par l’articulation entre prise et reprise. Notre proposition consiste, dans cette perspective, à préciser le rôle de l’expérience, et à rendre compte plus finement ...
Jacques Fontanille
doaj   +1 more source

Art et expérience corporelle

open access: yes, 2017
Ce carnet vis à accueillir les débats du séminaire organisé par Christine Vial Kayser pour Langarts en 2018/2019. Le concept se rattache à l’intuition du Pragmatisme que l’esprit dépend du corps qui est, « l’œil du cyclone, l’origine des coordonnées, le ...
Christine Vial Kayser
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Juré d'Assises : une expérience qui transforme.

open access: yes, 2015
Comment un citoyen lambda vit sa rencontre avec la Justice belge en tant que juré d’Assises ? Quels effets cette expérience engendre ? La Cour d’Assises est l’instance judiciaire la plus médiatisée, elle fascine par ses affaires et questionne par son ...
Seumois, Florence
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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