Results 71 to 80 of about 3,365,743 (244)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Expérience EDELWEISS 2

, 2009
Expérience Edelweiss 2, étude des Wimp's, matière noire de l ...
Lsm, Lsm
core   +1 more source

Une expérience

, 1926
L. P. Une expérience. In: La revue pédagogique, tome 89, Juillet-Décembre 1926. pp.
L., P.
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Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Expérience EDELWEISS 2

, 2005
Expérience Edelweiss 2, étude des Wimp's, matière noire de l ...
Lsm, Lsm
core   +1 more source

Saber ver el paisaje

Estudios Geográficos, 2010
Es preciso enseñar a ver el paisaje desde la geografía y difundirlo. Para ello se cuenta con abundantes recursos propios y con orientaciones renovadoras. Este saber mirar geográfico requiere conceptos, perspectiva y método, que se repasan en este trabajo,
Eduardo Martínez de Pisón
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Pratique du terrain et expérience des textes : une perspective africaine

Continents manuscrits, 2019
L’approche anthropologique des textes est-elle un moyen d’en faire advenir leur poéticité ? Telle est la question à laquelle j’essaie de répondre. Parce qu’elle sont à la croisée de l’anthropologie et de la littérature, les notions de « terrain » et d ...
Xavier Garnier
doaj   +1 more source

Expérience, expertise, expérimentation

, 2018
Chapitre de vulgarisationOn ne confond généralement pas, dans les jeux de langage, l’expérience vécue (par le malade souffrant) et l’expérience acquise (du praticien chevronné). La configuration du patient-expert bouscule ce confort et soulève un certain
Weber, Jean-Christophe
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