Results 91 to 100 of about 3,500,066 (302)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Résultats d'une enquête concernant les agents de lutte biologique contre l'acarien du cocotier Eriophyes guerreronis [PDF]

, 1980
Une enquête a été entreprise afin de trouver des ennemis naturels d'Eriophyes guerreronis, acarien ériophyide nuisible au cocotier. L'enquête a concerné 18 localités, y compris des régions indemnes.
Hall, R.A., Hussey, N.W., Mariau, Dominique   +2 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Premiers résultats d'une expérience clinale d'espacement avecPopulus trichocarpa [PDF]

, 1974
N. DÉCOURT, Maud Lemoine
openalex   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

A modern Fizeau experiment for education and outreach purposes

, 2010
On the occasion of the laser's 50th anniversary, we performed a modern Fizeau experiment, measuring the speed of light with a laser beam passing over the city centre of Marseille.
, A Sellé, Bobin J-L, Cornu A, D Guyomarc'h, Fizeau H, J M Laugier, M Knoop, O Morizot, S Ferri   +9 more
core   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

ANALYSE DE L’INFLUENCE DU MARKETING DE CONTENU A TRAVERS LES MEDIAS SOCIAUX SUR L’ATTACHEMENT A LA MARQUE

Revue Marocaine de Recherche en Management et Marketing, 2017
Les médias sociaux suscitent actuellement un grand intérêt pour les marques qui les ont intégrés dans leurs stratégies de web marketing, et y ont décelé l’opportunité de séduire, de convertiret de fidéliser leurs clients par l’interaction qu’ils offrent.
ABLA BERRADA, SIHAM SAHBANI, MOHAMMED BENAMAR   +2 more
doaj  

Une écologie ordinaire, en-deçà de l’écologie extraordinaire des figures héroïques ou des militants radicaux. Enquête sur le rapport des étudiants ordinaires au numérique

Interfaces Numériques
Face aux limites de ce que nous désignons par une « écologie extra-ordinaire » et au paradoxe nommé « Green Gap », ce travail a pour objectif de proposer une approche alternative en termes d’« écologie ordinaire », inspirée à la fois de l’approche du ...
Thomas Anh Ngoc HOANG, Magali PRODHOMME, Ingrid PLIVARD   +2 more
doaj   +1 more source