Results 91 to 100 of about 109,706 (265)

Biodisponibilité des polluants du sol : définition, caractérisation et utilisation potentielle dans la gestion des sites et sols pollués [PDF]

, 2009
National audienceL'effet toxique d'un polluant du sol vis-à-vis des organismes sera fonction de la concentration totale de ce polluant dans le sol et de sa biodisponibilité.
Caboche, Julien, Dabin, Claire, Denys, Sébastien, Dor, Frédéric, Feidt, Cyril, Floch-Barneaud, Adeline, Tack, Karine   +6 more
core   +1 more source

Condensed tannin changes along the digestive tract in lambs fed with sainfoin pellets or hazelnut skins [PDF]

, 2018
The variable anthelmintic efficacy of condensed tannins (CT) against gastrointestinal nematodes may depend on CT concentration, composition, or fate along the digestive tract.
Drake, Christopher, El-Korso, Ramzi, Gaudin, Elodie, Hoste, Hervé, Mueller-Harvey, Irene, Quijada, Jessica   +5 more
core   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

A database of chemical absorption in human skin with mechanistic modeling applications

Scientific Data
Whether from environmental and occupational hazards or from topical pharmaceuticals, the human skin comes into contact with various chemicals every day.
Jessica N. Stevens, Alyson K. Prockter, Hunter A. Fisher, Hien Tran, Marina V. Evans   +4 more
doaj   +1 more source

Le recours à l’Aide complémentaire santé : les enseignements d’une expérimentation sociale à Lille [PDF]

Le dispositif de l’Aide complémentaire santé (ACS) a été mis en place au 1er janvier 2005 afin d’inciter les ménages dont le niveau de vie se situe juste au dessus du plafond CMU-C à acquérir une couverture complémentaire santé (CS). Même si le nombre de
Caroline Despres, Florence Jusot, Jérôme Wittwer, Sophie Guthmuller   +3 more
core  

Representation of Sound Objects within Early-Stage Auditory Areas: A Repetition Effect Study Using 7T fMRI. [PDF]

, 2015
Environmental sounds are highly complex stimuli whose recognition depends on the interaction of top-down and bottom-up processes in the brain. Their semantic representations were shown to yield repetition suppression effects, i. e. a decrease in activity
Bourquin, N.M., Clarke, S., Da Costa, S., Knebel, J.F., Saenz, M., van der Zwaag, W.   +5 more
core   +4 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Is animal experimentation fundamental? A experimentação animal é fundamental?

Acta Cirúrgica Brasileira, 2009
The understanding about the utilization of experimental animals in scientific research and in teaching is many times a complex issue. Special attention needs to be paid to attain the understanding by the general public of the importance of animal ...
Armando José d'Acampora, Lucas Félix Rossi, Jorge Bins Ely, Zulmar Acciolli de Vasconcellos   +3 more
doaj   +1 more source