Results 171 to 180 of about 114,889,184 (267)

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Association between polyphenols and inhalation-induced oxidative stress in chronic lung diseases: A systematic review. [PDF]

Biomed Rep
Gulyaev AE, Nurgaziyev M, Ikromov A, Nurgaziyeva A, Baurzhan MB, Tekebayev K, Kairgeldina SA, Shulgau Z, Kossumov A, Katkenov N, Kozhakhmetov S, Kushugulova A, Sergazy S.   +12 more
europepmc   +1 more source

DE VIVO B. and AYUSO R. A. (Eds), 2015. Volume 157, Journal of Geochemical Exploration, Elsevier, October, 1-194. ISSN: 0375-6742.

, 2015
Ayuso, Robert, DE VIVO Benedetto, AYUSO Robert, DE VIVO, Benedetto   +3 more
core  

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Biomechanical Assessment Using MRI of Custom-Made Bovine Pericardial Tubes as Potential Aortic Replacements. [PDF]

Radiol Res Pract
Alblowi A, Vuissoz PA, Lin S, Bouchot O, Decourselle T, Felblinger J, Settembre N, Lalande A, Malikov S.   +8 more
europepmc   +1 more source

DE VIVO B. and AYUSO R. A. (Eds), 2015. Volume 156, Journal of Geochemical Exploration, Elsevier, September, 1-162. ISSN: 0375-6742.

, 2015
DE VIVO Benedetto, AYUSO, Robert, DE VIVO, Benedetto   +2 more
core  

Un patto tra generazioni per un nuovo welfare:anziani e giovani nell'era dell'intelligenza artificiale

L'articolo tratta del rapporto tra intelligenza artificiale e patto generazionale per affrontare la sfida del cambiamento in ...
Paola De Vivo
core  

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

The ethical and social significance of NAM terminology and definitions. [PDF]

NAM J
Elliott KC, Tanguay RL.
europepmc   +1 more source

DE VIVO B. and AYUSO R. A. (Eds), 2015. Volume 149, Journal of Geochemical Exploration, Elsevier, February, 1-146. ISSN: 0375-6742.

, 2015
AYUSO, Robert, DE VIVO, Benedetto
core